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PF-3084014

Catalog No.: 122950
Cas No.: 1290543-63-3
Purity : 98% 
122950 - PF-3084014 | CAS 1290543-63-3

Catalog number : 122950

CAS number : 1290543-63-3

分子式 : C27H41F2N5O 

分子量 : 489.64 

Iupac 化学名称 : (2S)-2-[[(2S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl]amino]-N-[1-[1-(2,2-dimethylpropylamino)-2-methylpropan-2-yl]imidazol-4-yl]pentanamide 

Smile : CCCC(C(=O)NC1=CN(C=N1)C(C)(C)CNCC(C)(C)C)NC2CCC3=CC(=CC(=C3C2)F)F

InChiKey : VFCRKLWBYMDAED-UHFFFAOYSA-N

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同义词PF 3084014; PF3084014; PF-03084014; PF 03084014; PF03084014 
英文同义词PF 3084014; PF3084014; PF-03084014; PF 03084014; PF03084014 
分子式C27H41F2N5O 
分子量489.64 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCCCC(C(=O)NC1=CN(C=N1)C(C)(C)CNCC(C)(C)C)NC2CCC3=CC(=CC(=C3C2)F)F
InChiKeyVFCRKLWBYMDAED-UHFFFAOYSA-N
InChiInChI=1S/C27H41F2N5O/c1-7-8-23(32-20-10-9-18-11-19(28)12-22(29)21(18)13-20)25(35)33-24-14-34(17-31-24)27(5,6)16-30-15-26(2,3)4/h11-12,14,17,20,23,30,32H,7-10,13,15-16H2,1-6H3,(H,33,35)
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PF-3084014 is a novel -secretase inhibitor that reduces amyloid-beta (Abeta) production with an in vitro IC(50) of 1.2 nM (whole-cell assay) to 6.2 nM (cell-free assay). 

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