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帕比司他

Catalog No.: 17022809
Cas No.: 404950-80-7
Purity : 98% 

帕比司他(LBH-589)是一种广谱HDAC抑制剂;低纳米分子浓度(IC50 =5-20 nM)的LBH589诱导细胞周期阻滞、凋亡、组蛋白(H3K9和H4K8)在MOLT - 4和Reh细胞中以时间和剂量依赖性的方式进行。

For research use only. We do not sell to patients.

Chemical Information

名称帕比司他
Iupac 化学名称Panobinostat 
同义词LBH-589; LBH589; NVP-LBH589 
英文同义词LBH-589; LBH589; NVP-LBH589 
分子式C₂₁H₂₃N₃O₂ 
分子量349.43 
SmileCc1c(c2ccccc2[nH]1)CCNCc3ccc(cc3)/C=C/C(=O)NO
InChiKeyFPOHNWQLNRZRFC-ZHACJKMWSA-N
InChiInChI=1S/C21H23N3O2/c1-15-18(19-4-2-3-5-20(19)23-15)12-13-22-14-17-8-6-16(7-9-17)10-11-21(25)24-26/h2-11,22-23,26H,12-14H2,1H3,(H,24,25)/b11-10+
Cas号404950-80-7
MDLMFCD09833242
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Formulation类白色至白色固体
纯度98% 
存储短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
可溶性可溶于DMSO;不溶于水
Handling
运输条件可在常温下运输
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

17022809 - 帕比司他 | CAS 404950-80-7

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