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PRI-724

Catalog No.: 16122785
Cas No.: 847591-62-2
Purity : 98% 
16122785 - PRI-724 | CAS 847591-62-2

Catalog number : 16122785

CAS number : 847591-62-2

分子式 : C33H32N4O4 

分子量 : 548.63 

Iupac 化学名称 : (6S,9aS)-N-benzyl-6-(4-hydroxybenzyl)-8-(naphthalen-1-ylmethyl)-4,7-dioxooctahydro-1H-pyrazino[1,2-a]pyrimidine-1-carboxamide 

Smile : C(C1=CC=CC=C1)NC(=O)N1[C@@H]2N(C(CC1)=O)[C@H](C(N(C2)CC2=CC=CC1=CC=CC=C21)=O)CC2=CC=C(C=C2)O

InChiKey : HQWTUOLCGKIECB-XZWHSSHBSA-N

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同义词PRI724; PRI-724; PRI 724; ICG001 isomer; ICG-001 isomer; ICG 001 isomer. 
英文同义词PRI724; PRI-724; PRI 724; ICG001 isomer; ICG-001 isomer; ICG 001 isomer. 
分子式C33H32N4O4 
分子量548.63 
外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
SmileC(C1=CC=CC=C1)NC(=O)N1[C@@H]2N(C(CC1)=O)[C@H](C(N(C2)CC2=CC=CC1=CC=CC=C21)=O)CC2=CC=C(C=C2)O
InChiKeyHQWTUOLCGKIECB-XZWHSSHBSA-N
InChiInChI=1S/C33H32N4O4/c38-27-15-13-23(14-16-27)19-29-32(40)35(21-26-11-6-10-25-9-4-5-12-28(25)26)22-30-36(18-17-31(39)37(29)30)33(41)34-20-24-7-2-1-3-8-24/h1-16,29-30,38H,17-22H2,(H,34,41)/t29-,30+/m0/s1
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PRI-724 is a potent, specific inhibitor of the canonical Wnt signaling pathway in cancer stem cells with potential antineoplastic activity. PRI-724 specifically inhibits the recruiting of beta-catenin with its coactivator CBP. 

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