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3PO

Catalog No.: 161227109
Cas No.: 13309-08-5
Purity : 98% 

3PO is a PFKFB3 (6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase) inhibitor. 3PO reduces glycolytic flux and suppresses glucose uptake. 3PO may be useful agents in combination with other drugs that inhibit cancer cell proliferation. PFKFB3 inhibitors suppress glucose uptake, which in turn causes an increase in autophagy. The addition of selective inhibitors of autophagy to 3PO and its more potent derivatives may prove useful as rational combinations for the treatment of cancer. 

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Chemical Information

名称3PO
Iupac 化学名称3PO 
同义词N/A 
英文同义词N/A 
分子式C13H10N2O 
分子量210.236 
Smilec1cc(cnc1)/C=C/C(=O)c2ccncc2
InChiKeyUOWGYMNWMDNSTL-ONEGZZNKSA-N
InChiInChI=1S/C13H10N2O/c16-13(12-5-8-14-9-6-12)4-3-11-2-1-7-15-10-11/h1-10H/b4-3+
Cas号13309-08-5
MDLMFCD00224002
Related CAS

Ordering Information

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Formulationcrystalline solid 
纯度98% 
存储3 years -20ºCpowder 
可溶性Soluble in DMSO 
Handling
运输条件Shipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

161227109 - 3PO | CAS 13309-08-5

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