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PI4KIIIbeta-IN-10

编号: 611907
Cas号: 1881233-39-1
纯度: 98% 

PI4KIIIbeta-IN-10 is the most potent PI4KIII inhibitor currently reported, with very minor off-target inhibition of PI4KIII related lipid kinases (IC50 = 3.6 nM). 


PI4KIIIbeta-IN-10 shows weak inhibition of PI3KC2 (IC50 1 M), PI3K (10 M), and PI4KIII (3 M), and <20% inhibition at concentrations up to 20 M for PI4K2, PI4K2, and PI3K. PI4KIIIbeta-IN-10 is also the most effective antiviral compound in a cellular model of hepatitis C virus replication, with the best balance of antiviral potency and low cellular toxicity.


 

仅供研究使用。 我们不向患者出售。

化学信息

名称PI4KIIIbeta-IN-10
Iupac 化学名称PI4KIIIbeta-IN-10 
同义词N-(5-(3-(N-(4-hydroxyphenyl)sulfamoyl)-4-methoxyphenyl)-4-methylthiazol-2-yl)pivalamide 
英文同义词N-(5-(3-(N-(4-hydroxyphenyl)sulfamoyl)-4-methoxyphenyl)-4-methylthiazol-2-yl)pivalamide 
分子式C22H25N3O5S2 
分子量475.58 
InChiKey
InChi
Cas号1881233-39-1
相关CAS号

订购信息

包装价格库存纯度备货期
大货询价询价询价
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外观性状crystalline solid 
纯度98% 
存储3 years -20&ordm;Cpowder 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature as non-hazardous chemical. 
海关编码
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Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

611907 - PI4KIIIbeta-IN-10 | CAS 1881233-39-1

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