武汉永璨生物科技有限公司
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抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
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Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
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JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
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NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
Others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
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Pyridines
Pyrimidines
Quinolines
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On Sale
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联系我们
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
Others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
工艺研发
订购信息
联系我们
公司简介
联系我们
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产品名字索引 L
Leuprolide
(Catalog# : 110603, Cas# :
53714-56-0
)
Leuprolide is an agonist at pituitary GnRH receptors.
LY2409881 trihydrochloride
(Catalog# : 101914, Cas# :
946518-60-1
)
LY2409881 trihydrochloride is a novel selective inhibitor of IKK2 with IC50 of 30 nM;
LHW090-A7
(Catalog# : 91810, Cas# :
1308256-94-1
)
Coming soon!
L189
(Catalog# : 91001, Cas# :
64232-83-3
)
L189 inhibits base excision repair (BER) and non-homologous end joining (NHEJ), which
Linagliptin
(Catalog# : 82608, Cas# :
668270-12-0
)
Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM.
Lurasidone hydrochloride
(Catalog# : 81313, Cas# :
367514-87-2
)
Lurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma, which
LRRK2-IN-1
(Catalog# : 81001, Cas# :
1234480-84-2
)
LRRK2-IN-1 is a cell-permeable, ATP competitive, potent, and selective LRRK2 inhibito
LY2874455
(Catalog# : 71801, Cas# :
1254473-64-7
)
1) Sponsor: Eli Lilly and Company.2) Phase:Phase 12) LY2874455 is potent, selective,
LDK378
(Catalog# : 52806, Cas# :
1032900-25-6
)
LDK378(Ceritinib) is potent inhibitor against ALK with IC50 of 0.2 nM, shows 40- and
LDN193189
(Catalog# : 52733, Cas# :
1062368-24-4
)
LDN193189(DM 3189) is a selective BMP signaling inhibitor, inhibits the transcription
LDN-214117
(Catalog# : 52707, Cas# :
1627503-67-6
)
LDN-214117 is a potent and selective ALK2 inhibitor with IC50 of 22 nM; > 100 fold
LDN-212854
(Catalog# : 52588, Cas# :
1432597-26-6
)
LDN-212854 is a potent and selectiveBMP receptorinhibitor with IC50 of 1.3 nM for ALK
LB-100
(Catalog# : 52511, Cas# :
1026680-07-8
)
LB-100 is a small-molecular protein phosphatase 2A(PP2A)inhibitor with IC50 of 0.85 M
LY-364947
(Catalog# : 52509, Cas# :
396129-53-6
)
LY364947 is a potent ATP-competitive inhibitor of TGFR-I with IC50 of 59 nM, exhibits
LH846
(Catalog# : 51504, Cas# :
639052-78-1
)
LH846 is a selective inhibitor of CK1 (IC50 values are 290 nM, 1.3 uM and 2.5 uM for
LY294002
(Catalog# : 52309, Cas# :
154447-36-6
)
LY294002 is the first synthetic molecule known to inhibitPI3K//withIC50of 0.5 M/0.57
LFM-A13
(Catalog# : 52206, Cas# :
244240-24-2
)
Selective Bruton's tyrosine kinase (BTK) inhibitor (IC50 = 2.5 M). Also inhibits poli
Luminespib ( NVP-AUY922 ; VER-52296 )
(Catalog# : 51703, Cas# :
747412-49-3
)
NVP-AUY922 is an experimental drug candidate for the treatment of cancer. It was disc
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
Dencatistat (STP938)
(Catalog# : 25177, Cas# :
2377000-84-3
)
Dencatistat 是一种口服生物可利用的小分子胞苷三磷酸合酶 1 (CTPS1)
DS-1001b
(Catalog# : 25178, Cas# :
1898207-64-1
)
DS-1001 是一种口服的脑渗透性突变 IDH1 选择性抑制剂。
Z57346765
(Catalog# : 25191, Cas# :
1016340-64-9
)
Z57346765 是一种 PGK1 特异性抑制剂,可降低 PGK1 糖酵解中代谢酶的
CBR-470-1
(Catalog# : 25192, Cas# :
2416095-06-0
)
CBR-470-1 是诱导 Nrf2 活性的糖酵解酶 PGK1 的抑制剂。
Safusidenib
(Catalog# : 25149, Cas# :
1898206-17-1
)
Safusidenib,也称为DS-1001,是一种口服异柠檬酸脱氢酶[NADP]细胞质(
HC-7366
(Catalog# : 25076, Cas# :
2803470-63-3
)
HC-7366 is a potent and selective activator of the general control nonderepressible 2
Flavopiridol ( 夫拉平度 )
(Catalog# : 237071, Cas# :
146426-40-6
)
Alvocidib is a synthetic dihydroxyflavone that is 5,7-dihydroxyflavone which is subst
AG-270
(Catalog# : 25176, Cas# :
2201056-66-6
)
MAT2A 抑制剂 AG-270 是一种口服的蛋氨酸腺苷转移酶 II α (MAT2A) 小分
AZD-5904
(Catalog# : 181121, Cas# :
618913-30-7
)
AZD5904是一个有效的口服生物利用率MPO抑制剂。在临床前研究中,AZ
ALT-007
(Catalog# : 25157, Cas# :
2035010-37-6
)
ALT-007 是一种口服生物可利用的 SPT 抑制剂,比多球菌素更有效,