武汉永璨生物科技有限公司
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抑制剂/受体激动剂
Angiogenesis
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Immunology & Inflammation
JAK/STAT
MAPK
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Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
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PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
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分子砌块
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Bromides
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Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
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技术服务
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订购信息
联系我们
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
Others
Nuclear Receptor
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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On Sale
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公司简介
联系我们
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产品名字索引 L
Leuprolide
(Catalog# : 110603, Cas# :
53714-56-0
)
Leuprolide is an agonist at pituitary GnRH receptors.
LY2409881 trihydrochloride
(Catalog# : 101914, Cas# :
946518-60-1
)
LY2409881 trihydrochloride is a novel selective inhibitor of IKK2 with IC50 of 30 nM;
LHW090-A7
(Catalog# : 91810, Cas# :
1308256-94-1
)
Coming soon!
L189
(Catalog# : 91001, Cas# :
64232-83-3
)
L189 inhibits base excision repair (BER) and non-homologous end joining (NHEJ), which
Linagliptin
(Catalog# : 82608, Cas# :
668270-12-0
)
Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM.
LRRK2-IN-1
(Catalog# : 81001, Cas# :
1234480-84-2
)
LRRK2-IN-1 is a cell-permeable, ATP competitive, potent, and selective LRRK2 inhibito
LY2874455
(Catalog# : 71801, Cas# :
1254473-64-7
)
1) Sponsor: Eli Lilly and Company.2) Phase:Phase 12) LY2874455 is potent, selective,
LDK378
(Catalog# : 52806, Cas# :
1032900-25-6
)
LDK378(Ceritinib) is potent inhibitor against ALK with IC50 of 0.2 nM, shows 40- and
LDN193189
(Catalog# : 52733, Cas# :
1062368-24-4
)
LDN193189(DM 3189) is a selective BMP signaling inhibitor, inhibits the transcription
LDN-214117
(Catalog# : 52707, Cas# :
1627503-67-6
)
LDN-214117 is a potent and selective ALK2 inhibitor with IC50 of 22 nM; > 100 fold
LDN-212854
(Catalog# : 52588, Cas# :
1432597-26-6
)
LDN-212854 is a potent and selectiveBMP receptorinhibitor with IC50 of 1.3 nM for ALK
LB-100
(Catalog# : 52511, Cas# :
1026680-07-8
)
LB-100 is a small-molecular protein phosphatase 2A(PP2A)inhibitor with IC50 of 0.85 M
LY-364947
(Catalog# : 52509, Cas# :
396129-53-6
)
LY364947 is a potent ATP-competitive inhibitor of TGFR-I with IC50 of 59 nM, exhibits
LH846
(Catalog# : 51504, Cas# :
639052-78-1
)
LH846 is a selective inhibitor of CK1 (IC50 values are 290 nM, 1.3 uM and 2.5 uM for
LY294002
(Catalog# : 52309, Cas# :
154447-36-6
)
LY294002 is the first synthetic molecule known to inhibitPI3K//withIC50of 0.5 M/0.57
LFM-A13
(Catalog# : 52206, Cas# :
244240-24-2
)
Selective Bruton's tyrosine kinase (BTK) inhibitor (IC50 = 2.5 M). Also inhibits poli
Luminespib ( NVP-AUY922 ; VER-52296 )
(Catalog# : 51703, Cas# :
747412-49-3
)
NVP-AUY922 is an experimental drug candidate for the treatment of cancer. It was disc
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
----
Methionine Adenosyltransferase (MAT)
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
----
Reactive Oxygen Species(ROS)
----
SOD
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolic Enzyme/Protease
----
PPAR
----
Proteasome
----
P450
----
Caspase
----
HSP
----
HIV Protease
----
PDE
----
MMP
----
Factor Xa
----
γ-secretase
----
Phospholipase
----
DPP4
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
NADPH-oxidase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
FPTase
----
RAR/RXR
----
Acetyl-CoA Carboxylase
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Glutaminase
----
Ketohexokinase(KHK)
----
Lipase
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
----
E1/E2/E3 Enzyme
----
PANK(pantothenate kinase)
----
Phosphoglycerate Dehydrogenase (PHGDH)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
----
CGRP-Receptor
----
TRP-Channel
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
----
Vps34
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
----
Notch
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
-- Nuclear Receptor
----
Androgen Receptor(AR)
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
Kartogenin ( KGN )
(Catalog# : 52215, Cas# :
4727-31-5
)
Kartogenin(KGN)是一种合成小分子,通过激活smad-4/5通路刺激软骨细
Imisopasem manganese ( M40403; GC4403 )
(Catalog# : 72602, Cas# :
218791-21-0
)
Imisopasem manganese ( M40403; GC4403 ) 是一种稳定的非肽类 MnSOD 类似物,
Apecotrep (BI 764198)
(Catalog# : 26A048, Cas# :
2311863-36-0
)
Apecotrep(BI 764198)是一种潜在的同类首创、口服、选择性的TRPC6抑
Pantothenate kinase-IN-2
(Catalog# : 26A038, Cas# :
902614-04-4
)
Pantothenate kinase-IN-2是一种泛酸激酶抑制剂,对PanK2的IC50值为92 nM,
BH-30643
(Catalog# : 26A047, Cas# :
3062177-59-4
)
BH-30643是一种新型、口服、非共价、大环、突变选择性OMNI-EGFR抑制
Gridegalutamide
(Catalog# : 26A044, Cas# :
2446929-86-6
)
格列德加鲁胺是一种具有口服生物利用度的雄激素受体(AR)降解
BMS-986365 (别名: CC-94676 )
(Catalog# : 25138, Cas# :
2446928-30-7
)
BMS-986365,也称为 CC-94676,是一种口服生物可利用的雄激素受体 (A
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
VAS3947
(Catalog# : 20302, Cas# :
869853-70-3
)
VAS3947是一种低微摩尔浓度的NADPH氧化酶活性的选择性抑制剂,既不