Selective Bruton's tyrosine kinase (BTK) inhibitor (IC50 = 2.5 M). Also inhibits polio-like kinase (Plk1) (IC50 = 37.36 M). Does not effect EGF receptor, insulin recptor, JAK-1 JAK-2, JAK-3, SYK or HCK (IC50 values are all >300 M). Anticancer and antileukemic agent.
For research use only. We do not sell to patients.