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LFM-A13

Catalog No.: 52206
Cas No.: 244240-24-2
Purity : 98% 
52206 - LFM-A13 | CAS 244240-24-2

Catalog number : 52206

CAS number : 244240-24-2

分子式 : C11H8Br2N2O2 

分子量 : 360 

Iupac 化学名称 : (Z)-2-cyano-N-(2,5-dibromophenyl)-3-hydroxybut-2-enamide 

Smile : C(#N)/C(/C(=O)NC1=C(C=CC(=C1)Br)Br)=C(\C)/O

InChiKey : UVSVTDVJQAJIFG-VURMDHGXSA-N

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同义词N/A 
英文同义词N/A 
分子式C11H8Br2N2O2 
分子量360 
外观yellow solid 
纯度98% 
可溶性Soluble in DMSO to 25 mM 
存储Store at -20ºCC (desiccating conditions). 
运输条件Shipped under ambient temperature 
SmileC(#N)/C(/C(=O)NC1=C(C=CC(=C1)Br)Br)=C(\C)/O
InChiKeyUVSVTDVJQAJIFG-VURMDHGXSA-N
InChiInChI=1S/C11H8Br2N2O2/c1-6(16)8(5-14)11(17)15-10-4-7(12)2-3-9(10)13/h2-4,16H,1H3,(H,15,17)/b8-6-
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Selective Bruton's tyrosine kinase (BTK) inhibitor (IC50 = 2.5 M). Also inhibits polio-like kinase (Plk1) (IC50 = 37.36 M). Does not effect EGF receptor, insulin recptor, JAK-1 JAK-2, JAK-3, SYK or HCK (IC50 values are all >300 M). Anticancer and antileukemic agent. 

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