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MAPK
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
Others
Nuclear Receptor
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
中间体
技术服务
定制合成
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订购信息
联系我们
公司简介
联系我们
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产品名字索引 L
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产品名字索引 L
Lonafarnib
(Catalog# : 16071008, Cas# :
193275-84-2
)
Lonafarnib is a farnesyl transferase inhibitor. Structurely, it is also a synthetic t
LJI308
(Catalog# : 16070904, Cas# :
1627709-94-7
)
LJI308 is a potent, and pan-RSK(p90 ribosomal S6 kinase) inhibitor withIC50of 6 nM, 4
LJH685
(Catalog# : 16070903, Cas# :
1627710-50-2
)
LJH685 is a potent pan-RSKinhibitor withIC50of 6 nM, 5 nM and 4 nM for RSK1, RSK2, an
LX1606 (Hippurate)
(Catalog# : 16062301, Cas# :
1137608-69-5
)
LX1606 is an orally bioavailable, small-molecule, tryptophan hydroxylase (TPH) inhibi
Lumateperone(ITI-007)
(Catalog# : 632801, Cas# :
313368-91-1
)
ITI-007 is an investigational atypical antipsychotic which is currently under develop
LGD-4033(Ligandrol)
(Catalog# : 030907, Cas# :
1165910-22-4
)
LGD-4033, also known as VK5211 and Ligandrol, is an investigational selective androge
LY-379268
(Catalog# : 011904, Cas# :
191471-52-0
)
Coming soon!
Lefamulin acetate
(Catalog# : 011808, Cas# :
1350636-82-6
)
Coming soon!
Lefamulin
(Catalog# : 011807, Cas# :
1061337-51-6
)
Coming soon!
L-165041
(Catalog# : 011316, Cas# :
79558-09-1
)
Coming soon!
Linsitinib
(Catalog# : 010819, Cas# :
867160-71-2
)
Linsitinib is highly potent, orally efficacious and highly selective, dual ATP-compet
Lestaurtinib
(Catalog# : 010815, Cas# :
111358-88-4
)
Lesraurtinib is an orally bioavailable indolocarbazole derivative with antineoplastic
LX7101
(Catalog# : 010802, Cas# :
1192189-69-7
)
LX7101 is a potent inhibitor of LIMK1/2, ROCK2 and PKA, with IC50 of 24/1.6, 10, and
Loratadine
(Catalog# : 010435, Cas# :
79794-75-5
)
Loratadine is a selective inverse peripheral histamine H1-receptor agonist with an IC
LY2584702 free base
(Catalog# : 122909, Cas# :
1082949-67-4
)
LY2584702 is an orally available inhibitor of p70S6K signaling; inhibits p70S6K and p
LY2584702 tosylate
(Catalog# : 122907, Cas# :
1082949-68-5
)
LY-2584702 tosylate salt is an orally available inhibitor of p70S6K signaling; inhibi
L-779450
(Catalog# : 122835, Cas# :
303727-31-3
)
L-779450 is a potent, selective and ATP-competitive Raf kinase inhibitor (IC50 = 10 n
LDN193189 Hydrochloride
(Catalog# : 122830, Cas# :
1062368-62-0
)
LDN193189 Hydrochloride is a selective BMP signaling inhibitor, inhibits the transcri
LCL161
(Catalog# : 122820, Cas# :
1005342-46-0
)
LCL161 is an orally bioavailable SMAC mimetic and inhibitor of Inhibitor of Apoptosis
Lexibulin
(Catalog# : 122803, Cas# :
917111-44-5
)
Lexibulin is an orally bioavailable small-molecule with tubulin-inhibiting, vascular-
LY2228820
(Catalog# : 122509, Cas# :
862507-23-1
)
LY2228820 is a novel and potent p38MAPK inhibitor (the IC50 for p38MAPK and p38MAPK w
LY2608204
(Catalog# : 122218, Cas# :
1234703-40-2
)
LY2608204 is a activator of glucokinase (GK) with EC50 of 42 nM.
L-778123 hydrochloride
(Catalog# : 121805, Cas# :
253863-00-2
)
L-778123 hydrochloride is an inhibitor of FPTase and GGPTase-I with IC50 of 2 nM and
Laquinimod
(Catalog# : 121506, Cas# :
248281-84-7
)
Laquinimod is an experimental immunomodulator developed by Active Biotech and Teva.
LY2811376
(Catalog# : 121435, Cas# :
1194044-20-6
)
LY2811376 is a BACE1 inhibitor with marked Ab-lowering effects in animal models.
LY2886721
(Catalog# : 121427, Cas# :
1262036-50-9
)
LY2886721 is an BACE inhibitor used for the treatment of Alzheimer's Disease.
Linifanib
(Catalog# : 121416, Cas# :
796967-16-3
)
Linifanib is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR, CSF-1R, F
LY2090314
(Catalog# : 5121102, Cas# :
603288-22-8
)
LY2090314 (LY) is a glycogen synthase kinase 3 inhibitor with preclinical efficacy in
LMK 235
(Catalog# : 120422, Cas# :
1418033-25-6
)
LMK 235 is a selective histone deacetylase (HDAC) 4 and HDAC5 inhibitor, which demons
LDN-57444
(Catalog# : 110606, Cas# :
668467-91-2
)
LDN-57444 is a Uch-L1 inhibitor with Ki= 0.4 M. Ubiquitin carboxy-terminal hydrolase
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产品分类
信号通路
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
----
Methionine Adenosyltransferase (MAT)
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
----
Reactive Oxygen Species(ROS)
----
SOD
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolic Enzyme/Protease
----
PPAR
----
Proteasome
----
P450
----
Caspase
----
HSP
----
HIV Protease
----
PDE
----
MMP
----
Factor Xa
----
γ-secretase
----
Phospholipase
----
DPP4
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
NADPH-oxidase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
FPTase
----
RAR/RXR
----
Acetyl-CoA Carboxylase
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Glutaminase
----
Ketohexokinase(KHK)
----
Lipase
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
----
E1/E2/E3 Enzyme
----
PANK(pantothenate kinase)
----
Phosphoglycerate Dehydrogenase (PHGDH)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
----
CGRP-Receptor
----
TRP-Channel
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
----
Vps34
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
----
Notch
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
-- Nuclear Receptor
----
Androgen Receptor(AR)
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
Kartogenin ( KGN )
(Catalog# : 52215, Cas# :
4727-31-5
)
Kartogenin(KGN)是一种合成小分子,通过激活smad-4/5通路刺激软骨细
Imisopasem manganese ( M40403; GC4403 )
(Catalog# : 72602, Cas# :
218791-21-0
)
Imisopasem manganese ( M40403; GC4403 ) 是一种稳定的非肽类 MnSOD 类似物,
Apecotrep (BI 764198)
(Catalog# : 26A048, Cas# :
2311863-36-0
)
Apecotrep(BI 764198)是一种潜在的同类首创、口服、选择性的TRPC6抑
Pantothenate kinase-IN-2
(Catalog# : 26A038, Cas# :
902614-04-4
)
Pantothenate kinase-IN-2是一种泛酸激酶抑制剂,对PanK2的IC50值为92 nM,
BH-30643
(Catalog# : 26A047, Cas# :
3062177-59-4
)
BH-30643是一种新型、口服、非共价、大环、突变选择性OMNI-EGFR抑制
Gridegalutamide
(Catalog# : 26A044, Cas# :
2446929-86-6
)
格列德加鲁胺是一种具有口服生物利用度的雄激素受体(AR)降解
BMS-986365 (别名: CC-94676 )
(Catalog# : 25138, Cas# :
2446928-30-7
)
BMS-986365,也称为 CC-94676,是一种口服生物可利用的雄激素受体 (A
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
VAS3947
(Catalog# : 20302, Cas# :
869853-70-3
)
VAS3947是一种低微摩尔浓度的NADPH氧化酶活性的选择性抑制剂,既不