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LDN193189

Catalog No.: 52733
Cas No.: 1062368-24-4
Purity : 98% 
52733 - LDN193189 | CAS 1062368-24-4

Catalog number : 52733

CAS number : 1062368-24-4

分子式 : C25H22N6 

分子量 : 406.48 

Iupac 化学名称 : 4-[6-(4-Piperazin-1-yl-phenyl)-pyrazolo[1,5-a]pyrimidin-3-yl]-quinoline 

Smile : N1(CCNCC1)C1=CC=C(C=C1)C=1C=NC=2N(C1)N=CC2C2=CC=NC1=CC=CC=C21

InChiKey : CDOVNWNANFFLFJ-UHFFFAOYSA-N

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同义词LDN193189;LDN 193189;LDN-193189 
英文同义词LDN193189;LDN 193189;LDN-193189 
分子式C25H22N6 
分子量406.48 
外观off-white solid 
纯度98% 
可溶性DMSO ��4mg/mL; Water ��30mg/mL; Ethanol <1mg/mL 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileN1(CCNCC1)C1=CC=C(C=C1)C=1C=NC=2N(C1)N=CC2C2=CC=NC1=CC=CC=C21
InChiKeyCDOVNWNANFFLFJ-UHFFFAOYSA-N
InChiInChI=1S/C25H22N6/c1-2-4-24-22(3-1)21(9-10-27-24)23-16-29-31-17-19(15-28-25(23)31)18-5-7-20(8-6-18)30-13-11-26-12-14-30/h1-10,15-17,26H,11-14H2
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LDN193189(DM 3189) is a selective BMP signaling inhibitor, inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively, exhibits 200-fold selectivity for BMP versus TGF- 

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