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L189

Catalog No.: 91001
Cas No.: 64232-83-3
Purity : 98% 
91001 - L189 | CAS 64232-83-3

Catalog number : 91001

CAS number : 64232-83-3

分子式 : C11H10N4OS 

分子量 : 246.29 

Iupac 化学名称 : (E)-6-amino-5-(benzylideneamino)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one 

Smile : NC1=C(C(NC(N1)=S)=O)/N=C/C1=CC=CC=C1

InChiKey : SAKOXVNKDMWWLF-AWNIVKPZSA-N

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同义词L189; L 189; L-189 
英文同义词L189; L 189; L-189 
分子式C11H10N4OS 
分子量246.29 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileNC1=C(C(NC(N1)=S)=O)/N=C/C1=CC=CC=C1
InChiKeySAKOXVNKDMWWLF-AWNIVKPZSA-N
InChiInChI=1S/C11H10N4OS/c12-9-8(10(16)15-11(17)14-9)13-6-7-4-2-1-3-5-7/h1-6H,(H4,12,14,15,16,17)/b13-6+
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L189 inhibits base excision repair (BER) and non-homologous end joining (NHEJ), which specifically sensitizes cancer cells to DNA damage and increases the cytotoxicity of DNA-damaging agents. L189 will not only provide insights into the cellular function of these enzymes but also serve as lead compounds for the development of anticancer agents. 

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