L189 inhibits base excision repair (BER) and non-homologous end joining (NHEJ), which specifically sensitizes cancer cells to DNA damage and increases the cytotoxicity of DNA-damaging agents. L189 will not only provide insights into the cellular function of these enzymes but also serve as lead compounds for the development of anticancer agents. 
仅供研究使用。 我们不向患者出售。
化学信息
| 名称 | L189 | 
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| Iupac 化学名称 | (E)-6-amino-5-(benzylideneamino)-2-thioxo-2,3-dihydropyrimidin-4(1H)-one | 
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| 同义词 | L189; L 189; L-189 | 
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| 英文同义词 | L189; L 189; L-189 | 
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| 分子式 | C11H10N4OS | 
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| 分子量 | 246.29 | 
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| Smile | NC1=C(C(NC(N1)=S)=O)/N=C/C1=CC=CC=C1 | 
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| InChiKey | SAKOXVNKDMWWLF-AWNIVKPZSA-N | 
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| InChi | InChI=1S/C11H10N4OS/c12-9-8(10(16)15-11(17)14-9)13-6-7-4-2-1-3-5-7/h1-6H,(H4,12,14,15,16,17)/b13-6+ | 
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| Cas号 | 64232-83-3 | 
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| 相关CAS号 |  | 
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| 外观性状 | Solid powder | 
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| 纯度 | 98% | 
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| 存储 | -20 ºC for 3 years | 
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| 可溶性 | Soluble in DMSO | 
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| 处理方式 |  | 
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| 运输条件 | Shipped under ambient temperature | 
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| 海关编码 |  | 
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| Targets |  | 
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| Mechanism |  | 
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| Cell study |  | 
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| Animal study |  | 
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| Clinical study |  | 
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