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抑制剂/受体激动剂
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Epigenetics
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Angiogenesis
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Cytoskeletal Signaling
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others
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Deuterated
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联系我们
+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
分子砌块
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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On Sale
中间体
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联系我们
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产品名字索引 L
LTURM-34
(Catalog# : 1710138, Cas# :
1879887-96-3
)
LTURM-34是一种新的有效的和选择性的DNA-PK抑制剂,可减轻体外对多
LY2606368 dihydrochloride
(Catalog# : 1710137, Cas# :
1234015-54-3
)
Prexasertib (LY2606368)是一个与ATP竞争的CHK1抑制剂带Ki值0.9 nmol/L。对于
LDC1267
(Catalog# : 179301, Cas# :
1361030-48-9
)
LDC1267显著降低小鼠乳腺癌和黑色素瘤转移依赖NK细胞。TAM酪氨酸激
N-(2,5-二羟基苄基)-5-氨基水杨酸
(Catalog# : 1791119, Cas# :
125697-93-0
)
Lavendustin C,也被称为HDBA和NSC 666251,是一种有效的表皮生长因子(
乐伐替尼(E7080)
(Catalog# : 52025, Cas# :
417716-92-8
)
乐伐替尼,又名E7080,是一种合成的、可口服的血管内皮生长因子
LXS-196
(Catalog# : 1781108, Cas# :
1874276-76-2
)
<span style="color:#34495E;font-family:"font-size:14px;background-color:
LDC4297(LDC044297)
(Catalog# : 178902, Cas# :
1453834-21-3
)
LDC4297也称为LCD044297,是一种有效、具有选择性的CDK7抑制剂。
LY3214996
(Catalog# : 2017887, Cas# :
1951483-29-6
)
LY-3214996是一种有效且具有选择性的,可用于口服的细胞外信号的
LTX-315
(Catalog# : 20178218, Cas# :
1345407-05-7
)
LTX-315是一种两性分子的阳离子肽可能用于治疗黑色素瘤、乳腺癌
LY 344864
(Catalog# : 20178212, Cas# :
186544-26-3
)
LY344864是一种选择性5-HT1F受体激动剂,在最近克隆的5 - HT1F受体上
盐酸LY 344864
(Catalog# : 2017828, Cas# :
1217756-94-9
)
LY344864 hydrochloride is a potent and selective 5-HT1F receptor agonist. It has an E
Lys05 trihydrochloride
(Catalog# : 17030102, Cas# :
1391426-24-6
)
Lys05, 或Lys01三盐酸化物,是一种有效的水溶性溶酶体自噬抑制剂。
拉帕替尼
(Catalog# : 17022807, Cas# :
231277-92-2
)
拉帕替尼(GW-572016) 是一种有效的EGFR和ErbB2抑制剂,IC50分别为10.8和
雷西那德
(Catalog# : 17022706, Cas# :
878672-00-5
)
雷西那德(RDEA594),是URAT1的一日一次抑制剂,是肾脏中调节尿酸排泄
LY3039478 ( Crenigacestat )
(Catalog# : 17021601, Cas# :
1421438-81-4
)
LY3039478 ( Crenigacestat ) 是一种选择性 NOTCH1 抑制剂,通过阻断 VEGFA/
LCI699
(Catalog# : 17021314, Cas# :
928134-65-0
)
LCI699(Osilodrostat)是一种强有力的抑制剂11β-羟化酶,酶催化合成皮质
lumateperone(Tosylate)
(Catalog# : 17012102, Cas# :
1187020-80-9
)
Lumateperone (ITI-722/ITI-007)是一种新型的双5HT2A受体拮抗剂/多巴胺磷蛋
Lys05
(Catalog# : 16123043, Cas# :
1391426-22-4
)
Lys05 is a potent lysosomal autophagy inhibitor. Lys05 is a previously undescribed di
LY-3177833
(Catalog# : 16123042, Cas# :
1627696-51-8
)
LY-3177833 is a potent and selective inhibitor of CDC7 (Cell Division Cycle 7-related
LY3009120
(Catalog# : 16123041, Cas# :
1454682-72-4
)
LY3009120, also known as DP-4978, is potent and selective pan-RAF inhibitor with pote
LY2334737
(Catalog# : 16123040, Cas# :
892128-60-8
)
LY2334737 is an orally available valproic acid ester of gemcitabine, a broad-spectrum
LY2109761
(Catalog# : 16123039, Cas# :
700874-71-1
)
LY2109761 is a novel transforming growth factor beta receptor type I and type II dual
Luliconazole
(Catalog# : 16123038, Cas# :
187164-19-8
)
Luliconazole is an azole antifungal drug. As a 1% topical cream, luliconazole is indi
Lubiprostone
(Catalog# : 16123037, Cas# :
333963-40-9
)
Lubiprostone, also known as RU-0211, is a medication used in the management of chroni
LOXO-101 (ARRY-470)
(Catalog# : 16123036, Cas# :
1223403-58-4
)
Larotrectinib, also known as ARRY-470 and LOXO-101, is an orally bioavailable, potent
Lomitapide free base
(Catalog# : 16123035, Cas# :
182431-12-5
)
Lomitapide is a MTP inhibitor. Lomitapid is a novel agent for the treatment of homozy
Lometrexol disodium
(Catalog# : 16123034, Cas# :
106400-81-1
)
Lometrexol is a folate analog antimetabolite with antineoplastic activity. As the 6R
LGK974 (WNT974)
(Catalog# : 16123033, Cas# :
1243244-14-5
)
LGK974, aslo known as is a selective and orally bioavailable Porcupine (PORCN) inhibi
Levobupivacaine free base
(Catalog# : 16123031, Cas# :
27262-47-1
)
Levobupivacaine is a local anaesthetic drug belonging to the amino amide group. It is
L67
(Catalog# : 16122828, Cas# :
325970-71-6
)
L67 is a DNA Ligase Inhibitor. L67 inhibited DNA ligases I and III. L67 is a simple c
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
PLX8394
(Catalog# : 20613, Cas# :
1393466-87-9
)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil 是一种有效的、高选择性的口服活性抑制剂,针对 Rho 相关
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib 是一种口服、有效、选择性的小分子抑制剂,针对 menin 和
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib是一种在研口服丝裂原活化蛋白激酶活化蛋白激酶2(MK2
Zongertinib ( BI 1810631 )
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] 是一种人表皮生长因子受体 2 (HER2) 抑制剂。
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib是一种作用于非受体酪氨酸蛋白激酶 (TYK2)靶点的抑制
RNK-05047
(Catalog# : 24008, Cas# :
2503036-46-0
)
RNK-05047 为BRD4降解剂,其在小鼠荷瘤异种移植模型中展现出显著抑
Asengeprast (FT011)
(Catalog# : 24009, Cas# :
1001288-58-9
)
Asengeprast (FT011) 是一种抗纤维化剂,降低胶原蛋白 I 和 III 的 mRNA
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) 是一种有效的 EGFR 抑制剂。
T-1095
(Catalog# : 24004, Cas# :
209746-59-8
)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).