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Inhibitors & Agonists
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Apoptosis
Autophagy
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DNA Damage
Epigenetics
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Immunology & Inflammation
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MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
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Amino Acids
Anilines
Boronic Acids
Bromides
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Deuterated
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Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
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Name Index I
IDE1
(Catalog# : 17030309, Cas# :
1160927-48-9
)
IDE1 is a potent cell-permeable definitive endoderm formation inducer (EC50 = 125 nM,
ISX-9
(Catalog# : 17022713, Cas# :
832115-62-5
)
ISX-9 is a neurogenic agent. Isx-9 promotes neurogenesis in vivo, enhancing the proli
Ixazomib (MLN-2238)
(Catalog# : 16123024, Cas# :
1072833-77-2
)
Ixazomib, also known as MLN-2238, is a potent proteasome inhibitor (PI) with potentia
Isovaleramide
(Catalog# : 16123023, Cas# :
541-46-8
)
Isovaleramide, also known as NPS-1776, is a drug potentially for the treatment of mig
Isosorbide Mononitrate
(Catalog# : 16123022, Cas# :
16051-77-7
)
Isosorbide Mononitrate is a drug used principally in the treatment of angina pectoris
IQ-1S
(Catalog# : 16123021, Cas# :
23146-22-7
)
IQ-1S is a potent and selective c-Jun N-Terminal Kinase Inhibitor. IQ-1S inhibits mur
Ingenol Mebutate
(Catalog# : 16123020, Cas# :
75567-37-2
)
Ingenol mebutate, also known as ingenol-3-angelate, is a substance found in the sap o
Imperatorin
(Catalog# : 16123019, Cas# :
482-44-0
)
Imperatorin, aslo known as Pentosalen, Marmelosin, is a furocoumarin and a phytochemi
Iloprost
(Catalog# : 16123018, Cas# :
78919-13-8
)
Iloprost is a drug used to treat pulmonary arterial hypertension (PAH), scleroderma,
IKK-16
(Catalog# : 16123017, Cas# :
873225-46-8
)
IKK-16 is a potent and slective inhibitor of IB kinase (IKK) (IC50 values are 40, 70
IDO-IN-1
(Catalog# : 16122822, Cas# :
914638-30-5
)
IDO-IN-1 is a potent and selective indoleamine-2,3-dioxygenase (IDO) inhibitor with I
Idalopirdine (Lu AE58054)
(Catalog# : 16122821, Cas# :
467459-31-0
)
Idalopirdine, also known as Lu AE58054 or Iladopirdine, is a potent and selective 5-H
IC87201
(Catalog# : 16122820, Cas# :
866927-10-8
)
IC87201 is a nNOS-PDZ/PSD-95-PDZ inhibitor. IC87201 showed great promise in cellular
ITSA-1 (ITSA1)
(Catalog# : 16122741, Cas# :
200626-61-5
)
ITSA-1 (ITSA1) is an HDAC activator via TSA suppression, but shows no activity toward
5-Iodotubercidin
(Catalog# : 16122729, Cas# :
24386-93-4
)
5-Iodotubercidin is a potent adenosine kinase inhibitor with IC50 of 26 nM. It inhibi
IMR-1A
(Catalog# : 6111507, Cas# :
331862-41-0
)
IMR-1A is the metabolite of IMR-1. IMR-1 is a novel class of Notch inhibitors targeti
Itacitinib
(Catalog# : 6111505, Cas# :
1334298-90-6
)
Itacitinib (INCB039110) is an oral selective JAK1 inhibitor. Itacitinib is an inh
IC261
(Catalog# : 611914, Cas# :
186611-52-9
)
IC261 is a novel inhibitor of CK1, triggers the mitotic checkpoint control. The IC50
Imeglimin
(Catalog# : 611811, Cas# :
775351-65-0
)
Imeglimin(EMD-387008) is the first in a new tetrahydrotriazine-containing class of or
IC-87114
(Catalog# : 160926004, Cas# :
371242-69-2
)
It Inhibits p110, p110 and p110 only at much higher concentrations. It does not inhib
Iniparib
(Catalog# : 16071103, Cas# :
160003-66-7
)
Iniparib, also known as BSI-201, is a small-molecule prodrug inhibitor of the nuclear
Idasanutlin (RG7388)
(Catalog# : 16070812, Cas# :
1229705-06-9
)
Idasanutlin; also known as RG7388 and RO5503781, is a highly potent and selective MDM
Istradefylline
(Catalog# : 16070809, Cas# :
155270-99-8
)
Istradefylline (KW-6002) is a selective antagonist at the A2A receptor. It has been f
Ilomastat
(Catalog# : 16070104, Cas# :
142880-36-2
)
Ilomastat, also known as GM6001 and galardin, is a broad-spectrum matrix metalloprote
IRAK-1-4 Inhibitor I
(Catalog# : 16062116, Cas# :
448906-42-1
)
IRAK-1-4 Inhibitor I
Ivosidenib
(Catalog# : 16053001, Cas# :
1448347-49-6
)
Ivosidenib is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1)
INCB 024360
(Catalog# : 032405, Cas# :
1204669-58-8
)
INCB 024360 is a potent and novel indoleamine-2,3 dioxygenase (IDO)inhibitor with an
5-Iodo-2-isopropyl-1-methyl-1H-imidazole
(Catalog# : 021701, Cas# :
851870-28-5
)
Coming soon!
Irbinitinib
(Catalog# : 011310, Cas# :
937263-43-9
)
Irbinitinib is a potent and selective HER2 inhibitor with IC50 of 8 nM, equipotent ag
INK-128
(Catalog# : 011121, Cas# :
1224844-38-5
)
INK 128 is a potent and selective mTOR inhibitor with IC50 of 1 nM; >200-fold less
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Zedoresertib
(Catalog# : 26A023, Cas# :
2243882-74-6
)
Zedoresertib (Debio 0123) is a brain-penetrant, highly selective WEE1 kinase inhibito
BEN-28010
(Catalog# : 26A022, Cas# :
3033961-38-2
)
BEN-28010 is a freely brain-penetrant, potent, and selective CHK1 inhibitor.
Tert-butyl 4-((2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carboxylate
(Catalog# : 26B007, Cas# :
3107291-07-3
)
Muvalaplin
(Catalog# : 20528, Cas# :
2565656-70-2
)
Muvalaplin is a small molecule that inhibits formation of Lp(a) by interfering with t
MAT2A-IN-22
(Catalog# : 26A021, Cas# :
2925330-18-1
)
MAT2A-IN-22 (Compound 29-1) is a blood-brain barrier-penetrant and orally active MAT2
AD-8007
(Catalog# : 26A018, Cas# :
1497439-74-3
)
AD-8007 is a selective and brain-penetrant inhibitor of acetyl CoA synthase 2 (ACSS2).
ZY-444
(Catalog# : 26A020, Cas# :
1802650-31-2
)
ZY-444 is an anti-cancer agent by inhibiting PC ( pyruvate carboxylase ) activity.
AD-5584
(Catalog# : 26A019, Cas# :
2306525-79-9
)
AD-5584 is a novel brain-permeable ACSS2 inhibitors.
IDB-003
(Catalog# : 26A017, Cas# :
3079716-11-0
)
IDB-003 inhibits MDA-MB-231 tumor growth in vivo.
Vafidemstat
(Catalog# : 18891, Cas# :
1357362-02-7
)
Vafidemstat, also known as ORY 2001, is a lysine-specific histone demethylase (LSD1)