IMR-1A
Catalog No: 6111507
CAS Number: 331862-41-0
Purity: 98%
IMR-1A is the metabolite of IMR-1. IMR-1 is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 mol/L.
IMR-1 prevents the recruitment of Maml1 to the NTC on chromatin, inhibits Notch target gene transcription, and dramatically inhibits tumor growth .
A decrease in colony formation of Notch-dependent cell lines is observed upon treatment with IMR-1 when compared with the control (DMSO).
For research use only. We do not sell to patients.
Chemical Information
| Name | IMR-1A |
|---|---|
| Iupac Chemical Name | IMR-1A |
| Synonyms | IMR1A; IMR 1A |
| Molecular Formula | C13H11NO5S2 |
| Molecular Weight | 325.36 |
| InChiKey | |
| InChi | |
| CAS Number | 331862-41-0 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
