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IMR-1A

Catalog No.: 6111507
Cas No.: 331862-41-0
Purity : 98% 
6111507 - IMR-1A | CAS 331862-41-0

Catalog number : 6111507

CAS number : 331862-41-0

Molecular Formula : C13H11NO5S2 

Molecular Weight : 325.36 

Iupac Chemical Name : IMR-1A 

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SynonymsIMR1A; IMR 1A 
Molecular FormulaC13H11NO5S2 
Molecular Weight325.36 
Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
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IMR-1A is the metabolite of IMR-1. IMR-1 is a novel class of Notch inhibitors targeting the transcriptional activation with IC50 of 6 mol/L.

IMR-1 prevents the recruitment of Maml1 to the NTC on chromatin, inhibits Notch target gene transcription, and dramatically inhibits tumor growth .
A decrease in colony formation of Notch-dependent cell lines is observed upon treatment with IMR-1 when compared with the control (DMSO).

 

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