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Inhibitors & Agonists
Angiogenesis
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Autophagy
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DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
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Antibody-drug Conjugate/ADC Related
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Boronic Acids
Bromides
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Chiral Compounds
Deuterated
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Iodos
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
Microbiology
Others
Building Blocks
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Amines
Amino Acids
Anilines
Boronic Acids
Bromides
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Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
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Name Index I
IWP L6
(Catalog# : 011109, Cas# :
1427782-89-5
)
IWP L6 is a Porcn inhibitor with EC50 of 0.5 nM.
Icotinib
(Catalog# : 011101, Cas# :
610798-31-7
)
Icotinib is an orally available quinazoline-based inhibitor of epidermal growth facto
IWP-3
(Catalog# : 010801, Cas# :
687561-60-0
)
IWP-3 is an inhibitor of Wnt production.
Isoquinolin-7-ylboronic acid
(Catalog# : 010612, Cas# :
1092790-21-0
)
This product is for custom synthesis.
IKK 16
(Catalog# : 010419, Cas# :
1186195-62-9
)
Coming soon!
IDO-IN-2
(Catalog# : 123002, Cas# :
914471-09-3
)
IDO-IN-2 is a potent IDO1 inhibitor(IC50=10 nM) with desirable pharmaceutical propert
INT-747
(Catalog# : 122905, Cas# :
459789-99-2
)
INT-747 is a potent and selective FXR agonist(EC50=99 nM) endowed with anticholestati
ICG-001
(Catalog# : 122801, Cas# :
780757-88-2
)
ICG-001 is a potent, specific inhibitor of the canonical Wnt signaling pathway in can
Ixabepilone
(Catalog# : 122307, Cas# :
219989-84-1
)
Ixabepilone is an epothilone B analog and nontaxane microtubule-stabilizing compound
Isavuconazole
(Catalog# : 120801, Cas# :
241479-67-4
)
Coming soon!
IRAK-1-4 Inhibitor I
(Catalog# : 110907, Cas# :
509093-47-4
)
IRAK-1-4 Inhibitor I is a IRAK-4 Inhibitor with IC50 of 200 nM, and is an anti-inflam
IWP-2
(Catalog# : 110602, Cas# :
686770-61-6
)
IWP-2 is an inhibitor of Wnt secretion and processing. It blocks Wnt-dependent signal
Indiplon
(Catalog# : 102701, Cas# :
325715-02-4
)
Indiplon is a pyrazolopyrimidine that acts as a high-affinity positive allosteric mod
INH6
(Catalog# : 102620, Cas# :
1001753-24-7
)
INH6 is a potent Hec1 inhibitor, which specifically disrupts the Hec1/Nek2 interactio
INH1
(Catalog# : 102606, Cas# :
313553-47-8
)
INH1 is a small molecule targeting the Hec1/Nek2 mitotic pathway suppresses tumor cel
ITD-1
(Catalog# : 101902, Cas# :
1099644-42-4
)
ITD-1 is a selective inhibitor of TGF- signaling, displays little or no inhibition of
INCB8761 (PF-4136309)
(Catalog# : 92210, Cas# :
857679-55-1
)
INCB8761(PF-4136309) is a potent, selective, and orally bioavailable CCR2 antagonist.
IN00076730
(Catalog# : 91816, Cas# :
1454700-89-0
)
Coming soon!
3-(3-Iodophenyl)propanoic acid
(Catalog# : 90712, Cas# :
68034-75-3
)
Coming soon!
3-(4-Iodophenyl)propionic acid
(Catalog# : 90711, Cas# :
1643-29-4
)
Coming soon!
Ipragliflozin
(Catalog# : 82604, Cas# :
761423-87-4
)
Ipragliflozin (ASP1941) is a highly potent and selective SGLT2 inhibitor with IC50 of
Indole-3-Acetamide
(Catalog# : 81920, Cas# :
879-37-8
)
Coming soon!
4-iodo-7H-pyrrolo[2,3-d]pyrimidine
(Catalog# : 81005, Cas# :
1100318-96-4
)
Coming soon!
3-Iodo-4-(trifluoromethoxy)benzoic acid
(Catalog# : 80316, Cas# :
1110709-70-0
)
Coming soon!
3-iodo-4-isopropylbenzoic acid
(Catalog# : 80313, Cas# :
99059-64-0
)
Coming soon!
IDO inhibitor 1
(Catalog# : 72806, Cas# :
1204669-37-3
)
IDO is an enzyme that catalyzes the degradation of the essential amino acid L-tryptop
Imisopasem-manganese(M40403)
(Catalog# : 72602, Cas# :
218791-21-0
)
M40403 is a low molecular weight, synthetic manganese containing superoxide dismutase
ICI118551(HCl)
(Catalog# : 60809, Cas# :
72795-01-8
)
Highly selective 2 adrenoceptor antagonist (Ki values are 1.2, 120 and 257 nM at 2, 1
Ivacaftor
(Catalog# : 52805, Cas# :
873054-44-5
)
Ivacaftor (VX-770) is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR wit
Ispinesib
(Catalog# : 52747, Cas# :
336113-53-2
)
Ispinesib (SB-715992) is a potent, specific and reversible inhibitor of KSP (HsEg5) w
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Zedoresertib
(Catalog# : 26A023, Cas# :
2243882-74-6
)
Zedoresertib (Debio 0123) is a brain-penetrant, highly selective WEE1 kinase inhibito
BEN-28010
(Catalog# : 26A022, Cas# :
3033961-38-2
)
BEN-28010 is a freely brain-penetrant, potent, and selective CHK1 inhibitor.
Tert-butyl 4-((2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno[2,3-d]pyrimidin-4-yl)amino)piperidine-1-carboxylate
(Catalog# : 26B007, Cas# :
3107291-07-3
)
Muvalaplin
(Catalog# : 20528, Cas# :
2565656-70-2
)
Muvalaplin is a small molecule that inhibits formation of Lp(a) by interfering with t
MAT2A-IN-22
(Catalog# : 26A021, Cas# :
2925330-18-1
)
MAT2A-IN-22 (Compound 29-1) is a blood-brain barrier-penetrant and orally active MAT2
AD-8007
(Catalog# : 26A018, Cas# :
1497439-74-3
)
AD-8007 is a selective and brain-penetrant inhibitor of acetyl CoA synthase 2 (ACSS2).
ZY-444
(Catalog# : 26A020, Cas# :
1802650-31-2
)
ZY-444 is an anti-cancer agent by inhibiting PC ( pyruvate carboxylase ) activity.
AD-5584
(Catalog# : 26A019, Cas# :
2306525-79-9
)
AD-5584 is a novel brain-permeable ACSS2 inhibitors.
IDB-003
(Catalog# : 26A017, Cas# :
3079716-11-0
)
IDB-003 inhibits MDA-MB-231 tumor growth in vivo.
Vafidemstat
(Catalog# : 18891, Cas# :
1357362-02-7
)
Vafidemstat, also known as ORY 2001, is a lysine-specific histone demethylase (LSD1)