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IDE1

Catalog No.: 17030309
Cas No.: 1160927-48-9
Purity : 98% 
17030309 - IDE1 | CAS 1160927-48-9

Catalog number : 17030309

CAS number : 1160927-48-9

Molecular Formula : C15H18N2O5 

Molecular Weight : 306.32 

Iupac Chemical Name : 7-[2-(2-Carboxybenzylidene)hydrazinyl]-7-oxoheptanoic acid 

Smile : C(=O)(O)C1=C(C=NNC(CCCCCC(=O)O)=O)C=CC=C1

InChiKey : ABKJCDILEUEJSH-UHFFFAOYSA-N

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SynonymsIDE1; IDE-1; IDE 1 
Molecular FormulaC15H18N2O5 
Molecular Weight306.32 
Appearanceoff-white solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
SmileC(=O)(O)C1=C(C=NNC(CCCCCC(=O)O)=O)C=CC=C1
InChiKeyABKJCDILEUEJSH-UHFFFAOYSA-N
InChiInChI=1S/C15H18N2O5/c18-13(8-2-1-3-9-14(19)20)17-16-10-11-6-4-5-7-12(11)15(21)22/h4-7,10H,1-3,8-9H2,(H,17,18)(H,19,20)(H,21,22)
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IDE1 is a potent cell-permeable definitive endoderm formation inducer (EC50 = 125 nM, ESC) similar to IDE 2 (ab145223). IDE1 induces Sox17 expression. It also activates TGF- signaling and downstream Smad2 phosphorylation. IDE1 upregulates Nodal expression. 

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