Itacitinib
Catalog No: 6111505
CAS Number: 1334298-90-6
Purity: 98%
Itacitinib (INCB039110) is an oral selective JAK1 inhibitor.
Itacitinib is an inhibitor of the Janus kinases (JAKs) with selectivity for JAK1. Itacitinib potently inhibits OCT2-mediated uptake of creatinine as well as MATE1-/MATE2-K-mediated efflux of creatinine. Itacitinib causes a dose-dependent decrease in transcellular transport of creatinine with weaker net inhibition compared with the effects on individual transporters.
For research use only. We do not sell to patients.
Chemical Information
| Name | Itacitinib |
|---|---|
| Iupac Chemical Name | Itacitinib |
| Synonyms | INCB039110; INCB-039110; INCB 039110 |
| Molecular Formula | C26H23F4N9O |
| Molecular Weight | 553.51 |
| InChiKey | |
| InChi | |
| CAS Number | 1334298-90-6 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
