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IC87201

Catalog No.: 16122820
Cas No.: 866927-10-8
Purity : 98% 
16122820 - IC87201 | CAS 866927-10-8

Catalog number : 16122820

CAS number : 866927-10-8

Molecular Formula : C13H10Cl2N4O 

Molecular Weight : 309.15 

Iupac Chemical Name : IC87201 

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SynonymsIC-87201; IC 87201 
Molecular FormulaC13H10Cl2N4O 
Molecular Weight309.15 
Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
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IC87201 is a nNOS-PDZ/PSD-95-PDZ inhibitor. IC87201 showed great promise in cellular experiments and animal models of ischemic stroke and pain. IC87201 inhibited the in vitro binding of nNOS with PSD95, without inhibiting nNOS catalytic activity. nNOS-PSD95 interaction is important in maintaining hypersensitivity in acute and chronic pain. Disruption of the nNOS-PSD95 interaction provides a novel approach to obtain selective anti-hyperalgesic compounds. 

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