SU5402
Catalog No.: 174191
Cas No.: 215543-92-3
Purity : 98% by HNMR/HPLC
Catalog number : 174191
CAS number : 215543-92-3
Molecular Formula : C17H16N2O3
Molecular Weight : 296.3
Iupac Chemical Name : (Z)-3-(4-methyl-2-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid
Smile : O=C(O)CCC1=C(/C=C2C(NC3=C\2C=CC=C3)=O)NC=C1C
InChiKey : JNDVEAXZWJIOKB-JYRVWZFOSA-N
| Packaging | Price | Availability | Purity | Estimated Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry |
| Synonyms | SU5402;SU-5402;SU 5402 |
|---|---|
| Molecular Formula | C17H16N2O3 |
| Molecular Weight | 296.3 |
| Appearance | yellow powder |
| Purity | 98% by HNMR/HPLC |
| Solubility | Soluble in DMSO, not in water |
| Storage | 3 years -20ºCpowder 6 months-80ºCin solvent |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| Smile | O=C(O)CCC1=C(/C=C2C(NC3=C\2C=CC=C3)=O)NC=C1C |
| InChiKey | JNDVEAXZWJIOKB-JYRVWZFOSA-N |
| InChi | InChI=1S/C17H16N2O3/c1-10-9-18-15(11(10)6-7-16(20)21)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21)/b13-8- |
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SU5402 is a fibroblast growth factor receptor (FGFR)-specific tyrosine kinase inhibitor. Multiple myeloma studies suggest that SU 5402 inhibits FGFR3 phosphorylation in vitro. SU5402 is also very potent in inhibiting VEGFR, and PDGFR. Research shows that it inhibits embryonic left-right determination and exhibits potent anticancer activity in vitro and in vivo.
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