SU5402 Catalog No : 174191

Product Name	SU5402
Iupac Chemical Name	(Z)-3-(4-methyl-2-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid
Synonyms	SU5402;SU-5402;SU 5402
Molecular Formula	C17H16N2O3
Molecular Weight	296.3
Smile	O=C(O)CCC1=C(/C=C2C(NC3=C\2C=CC=C3)=O)NC=C1C
InChiKey	JNDVEAXZWJIOKB-JYRVWZFOSA-N
InChi	InChI=1S/C17H16N2O3/c1-10-9-18-15(11(10)6-7-16(20)21)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21)/b13-8-
Cas	215543-92-3

Appearance	yellow powder
Purity	98% by HNMR/HPLC
Solubility	Soluble in DMSO, not in water
Storage	3 years -20ºCpowder 6 months-80ºCin solvent
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical.
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SU5402 is a fibroblast growth factor receptor (FGFR)-specific tyrosine kinase inhibitor. Multiple myeloma studies suggest that SU 5402 inhibits FGFR3 phosphorylation in vitro. SU5402 is also very potent in inhibiting VEGFR, and PDGFR. Research shows that it inhibits embryonic left-right determination and exhibits potent anticancer activity in vitro and in vivo.

SU5402 Catalog No : 174191

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