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SU5402

Catalog No.: 174191
Cas No.: 215543-92-3
Purity : 98% by HNMR/HPLC
174191 - SU5402 | CAS 215543-92-3

Catalog number : 174191

CAS number : 215543-92-3

Molecular Formula : C17H16N2O3 

Molecular Weight : 296.3 

Iupac Chemical Name : (Z)-3-(4-methyl-2-((2-oxoindolin-3-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid 

Smile : O=C(O)CCC1=C(/C=C2C(NC3=C\2C=CC=C3)=O)NC=C1C

InChiKey : JNDVEAXZWJIOKB-JYRVWZFOSA-N

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SynonymsSU5402;SU-5402;SU 5402 
Molecular FormulaC17H16N2O3 
Molecular Weight296.3 
Appearanceyellow powder 
Purity98% by HNMR/HPLC
SolubilitySoluble in DMSO, not in water 
Storage3 years -20ºCpowder 6 months-80ºCin solvent 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
SmileO=C(O)CCC1=C(/C=C2C(NC3=C\2C=CC=C3)=O)NC=C1C
InChiKeyJNDVEAXZWJIOKB-JYRVWZFOSA-N
InChiInChI=1S/C17H16N2O3/c1-10-9-18-15(11(10)6-7-16(20)21)8-13-12-4-2-3-5-14(12)19-17(13)22/h2-5,8-9,18H,6-7H2,1H3,(H,19,22)(H,20,21)/b13-8-
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SU5402 is a fibroblast growth factor receptor (FGFR)-specific tyrosine kinase inhibitor. Multiple myeloma studies suggest that SU 5402 inhibits FGFR3 phosphorylation in vitro. SU5402 is also very potent in inhibiting VEGFR, and PDGFR.  Research shows that it inhibits embryonic left-right determination and exhibits potent anticancer activity in vitro and in vivo. 

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