SNG-1153
Catalog No: 21228
CAS Number: 1446712-19-1
Purity: 98% Min.
SNG-1153 is a modulator of estrogen receptor ER-alpha36.
For research use only. We do not sell to patients.
Chemical Information
| Name | SNG-1153 |
|---|---|
| Iupac Chemical Name | 3,5,7-Trihydroxy-8-(3-methyl-but-2-enyl)-2-(4-trifluoromethyl-phenyl)-chromen-4-one |
| Synonyms | SNG1153; SNG-1153; SNG 1153 |
| Molecular Formula | C21H17F3O5 |
| Molecular Weight | 406.3572 |
| Smile | O=C1C(O)=C(C2=CC=C(C(F)(F)F)C=C2)OC3=C1C(O)=CC(O)=C3C/C=C(C)\C |
| InChiKey | OXHMDMVBLQNMGP-UHFFFAOYSA-N |
| InChi | InChI=1S/C21H17F3O5/c1-10(2)3-8-13-14(25)9-15(26)16-17(27)18(28)19(29-20(13)16)11-4-6-12(7-5-11)21(22,23)24/h3-7,9,25-26,28H,8H2,1-2H3 |
| CAS Number | 1446712-19-1 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% Min. |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
1: Chen M, Turhan AG, Ding H, Lin Q, Meng K, Jiang X. Targeting BCR-ABL+ stem/progenitor cells and BCR-ABL-T315I mutant cells by effective inhibition of the BCR-ABL-Tyr177-GRB2 complex. Oncotarget. 2017 Jul 4;8(27):43662-43677. doi: 10.18632/oncotarget.18216. PubMed PMID: 28599273; PubMed Central PMCID: PMC5546432.
2: Liu S, Guo Y, Wang J, Zhu H, Han Y, Jin M, Wang J, Zhou C, Ma J, Lin Q, Wang Z, Meng K, Fu X. A novel anticancer agent SNG1153 inhibits growth of lung cancer stem/progenitor cells. Oncotarget. 2016 Jul 19;7(29):45158-45170. doi: 10.18632/oncotarget.9783. PubMed PMID: 27281614; PubMed Central PMCID: PMC5216713.
Chemical Structure
