Senaparib
Catalog No: 20103002
CAS Number: 1401682-78-7
Purity: ≧98.0%
Senaparib (IMP4297) is a novel agent targeting PARP (poly-ADP ribose polymerase) with strong antitumor activity in preclinical studies. Senaparib demonstrated encouraging clinical benefit and a favorable tolerability profile in patients with advanced solid tumour.
For research use only. We do not sell to patients.
Chemical Information
| Name | Senaparib |
|---|---|
| Iupac Chemical Name | 5-fluoro-1-({4-fluoro-3-[4-(pyrimidin-2-yl)piperazine-1-carbonyl]phenyl}methyl)quinazoline-2,4(1H,3H)-dione |
| Synonyms | Senaparib ; IMP4297 ; IMP 4297 ; IMP-4297 ; |
| Molecular Formula | C24H20F2N6O3 |
| Molecular Weight | 478.4598 |
| Smile | O=C(N1)N(CC2=CC=C(F)C(C(N3CCN(C4=NC=CC=N4)CC3)=O)=C2)C5=C(C(F)=CC=C5)C1=O |
| InChiKey | VBTUJTGLLREMNW-UHFFFAOYSA-N |
| InChi | InChI=1S/C24H20F2N6O3/c25-17-6-5-15(14-32-19-4-1-3-18(26)20(19)21(33)29-24(32)35)13-16(17)22(34)30-9-11-31(12-10-30)23-27-7-2-8-28-23/h1-8,13H,9-12,14H2,(H,29,33,35) |
| CAS Number | 1401682-78-7 |
| Related CAS | 1401683-39-3 (HCl) 1401682-78-7 (free base) |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid to white solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation. |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
