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Inhibitors & Agonists
Angiogenesis
Anti-infection
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Autophagy
Cell Cycle
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DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Name Index G
GSK1292263
(Catalog# : 121430, Cas# :
1032823-75-8
)
GSK1292263 is a novel GPR119 receptor agonist used for the treatment of type 2 diabet
GSK1904529A
(Catalog# : 121428, Cas# :
1089283-49-7
)
GSK1904529A is a selective inhibitor of IGF-1R and IR with IC50 of 27 nM and 25 nM, &
GDC-0941
(Catalog# : 120115, Cas# :
957054-30-7
)
GDC-0941 is a potent inhibitor of PI3K/ with IC50 of 3 nM, with modest selectivity ag
GANT 61
(Catalog# : 120114, Cas# :
500579-04-4
)
GANT 61 is a small molecule inhibitor of Gli1 and Gli2.
GSK-1070916
(Catalog# : 111011, Cas# :
942918-07-2
)
GSK1070916 is a reversible and ATP-competitive inhibitor of Aurora B/C with IC50 of 3
GSK269962A
(Catalog# : 102206, Cas# :
850664-21-0
)
GSK269962A(CAS 850664-21-0) is a potent ROCK inhibitor (IC50 values are 1.6 and 4 nM
Gandotinib(LY2784544)
(Catalog# : 91415, Cas# :
1229236-86-5
)
Gandotinib is an orally bioavailable imidazopyridazine and inhibitor of Janus kinase
GW 627368
(Catalog# : 91003, Cas# :
439288-66-1
)
GW 627368X is a potent and selective competitive antagonist of the EP4 receptor with
GDC-0810 ( Brilanestrant , ARN-810 )
(Catalog# : 90731, Cas# :
1365888-06-7
)
GDC-0810 (Brilanestrant, ARN-810, RG6046) is a selective estrogen receptor degrader (
G007-LK
(Catalog# : 62908, Cas# :
1380672-07-0
)
G007-LK is specific tankyrase 1/2 inhibitor.G007-LK (66) displayed high selectivity t
GDC-0349
(Catalog# : 62702, Cas# :
1207360-89-1
)
GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR.
Galeterone
(Catalog# : 62003, Cas# :
851983-85-2
)
Galeterone(VN/124-1,TOK001) is a highly selective, multi-targeted, oral small molecul
Gimeracil
(Catalog# : 52804, Cas# :
103766-25-2
)
Gimeracil(Gimestat) is an inhibitor of dihydropyrimidine dehydrogenase (DPYD), which
GSK 525762A
(Catalog# : 52745, Cas# :
1260907-17-2
)
GSK 525762A (I-BET 762) is an inhibitor for BET proteins with IC50 of ~35 nM.
GSK429286A
(Catalog# : 52629, Cas# :
864082-47-3
)
GSK429286A is a selective inhibitor of ROCK1 and ROCK2 with IC50 of 14 nM and 63 nM,
GSK1059615
(Catalog# : 52628, Cas# :
958852-01-2
)
GSK1059615 is a dual inhibitor of PI3K/// (reversible) and mTOR with IC50 of 0.4 nM/0
GKT137831
(Catalog# : 52627, Cas# :
1218942-37-0
)
GKT137831 is a novel and specific dual Nox1/Nox4 inhibitor with Ki of 14040 nM and 11
GSK2636771
(Catalog# : 52618, Cas# :
1372540-25-4
)
GSK2636771 is a potent, orally bioavailable and selective inhibitor of PI3K (0.89 nM)
GS-7340
(Catalog# : 52611, Cas# :
379270-37-8
)
GS-7340(Tenofovir alafenamide) is a prodrug of tenofovir (TFV) that more efficiently
GSK2110183
(Catalog# : 52584, Cas# :
1047634-63-8
)
GSK2110183 is an orally bioavailable, selective, ATP-competitive and potent pan-Akt i
GW788388
(Catalog# : 52305, Cas# :
452342-67-5
)
GW788388 is a potent and selective inhibitor of ALK5 with IC50 of 18 nM, also inhibit
GNF-5
(Catalog# : 52216, Cas# :
778277-15-9
)
GNF-5, an analogue of GNF-2 with improved pharmacokinetic properties, is a selective
GNF-2
(Catalog# : 52301, Cas# :
778270-11-4
)
GNF-2 is a highly selective non-ATP competitive inhibitor of oncogenic Bcr-Abl activi
GS967
(Catalog# : 52216, Cas# :
1262618-39-2
)
GS967 is a novel, potent, and selective inhibitor of cardiac late sodium current(late
GBR 12935 dihydrochloride
(Catalog# : 52404, Cas# :
67469-81-2
)
GBR 12935 2Hcl is a potent, and selective dopamine reuptake inhibitor.
GSK126
(Catalog# : 52208, Cas# :
1346574-57-9
)
GSK126 is a potent, highly selectiveEZH2 methyltransferaseinhibitor withIC50of 9.9 nM
GSK503
(Catalog# : 51805, Cas# :
1346572-63-1
)
GSK-503 is a potent EZH2 inhibitor with potential anticancer activity. Reference: 1.
GW9662
(Catalog# : 52304, Cas# :
22978-25-2
)
GW9662 is a selective PPAR antagonist forPPARwithIC50of 3.3 nM, with at least 100 to
GNE-317
(Catalog# : 52215, Cas# :
1394076-92-6
)
GNE-317 is a potent, brain-penetrantPI3Kinhibitor
Genz-123346
(Catalog# : S1419, Cas# :
491833-30-8
)
Genz-123346 free base is an inhibitor of GL1 synthase that blocks the conversion of c
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Dabogratinib ( TYRA-300 )
(Catalog# : 24073, Cas# :
2800223-30-5
)
Dabogratinib ( TYRA-300 ) is an Oral Selective FGFR3 Inhibitor (IC50 = 11 nM) for the
AF710B
(Catalog# : 25205, Cas# :
N/A
)
AF710B is a highly selective and potent allosteric agonist for M1 muscarinic and σ1
MAT2A inhibitor 5
(Catalog# : 25204, Cas# :
2957874-18-7
)
MAT2A inhibitor 5 has a high potency for inhibiting MAT2A and a remarkable selectivit
(Rac)-AF710B
(Catalog# : 24083, Cas# :
1235733-73-9
)
AF-710B is an agonist of sigma and M1 muscarinic receptors; AF710B is an enantiomer o
Flurpiridaz-nonradiolabeled
(Catalog# : 25203, Cas# :
863888-33-9
)
Flurpiridazis a promising novel cardiac PET imaging tracer formed by the radiolabelin
Flurpiridaz-Precursor
(Catalog# : 25202, Cas# :
863888-32-8
)
Flurpiridaz-Precursor in stock.
KL1333
(Catalog# : 25201, Cas# :
1800405-30-4
)
KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinon
Palupiprant ( E7046 )
(Catalog# : 24055, Cas# :
1369489-71-3
)
E7046 is a potent and selective antagonist of the type 4 prostaglandin E2 (PGE2) rece
Oveporexton ( TAK-861 )
(Catalog# : 25194, Cas# :
2460722-04-5
)
Oveporexton isan oral small molecule selective orexin type-2 receptor (OX2R) agonist.
VT-3989
(Catalog# : 25200, Cas# :
2506273-81-8
)
VT3989, a first-in-class potent oral TEAD palmitoylation inhibitor, disrupts YAP tran