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Inhibitors & Agonists
Angiogenesis
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Autophagy
Cell Cycle
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DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
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Iodos
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Name Index G
GSK-5959
(Catalog# : 1811266, Cas# :
901245-65-6
)
GSK-5959 is a potent and selective BRPF1 bromodomain inhibitor (IC50 = 80 nM).
GW-870086
(Catalog# : 1811263, Cas# :
827319-43-7
)
GW-870086 is a glucocorticoid receptor agonist potentially for the treatment of asthm
GSK9311
(Catalog# : 1811233, Cas# :
1923851-49-3
)
GSK9311 is a potent and highly selective inhibitor of the BRPF bromodomain (BRPDF1 pI
GW1100
(Catalog# : 1811231, Cas# :
306974-70-9
)
GW1100 is a a selective antagonist of GPR40.
GW6471
(Catalog# : 181151, Cas# :
880635-03-0
)
GW6471 is a PPAR α antagonist (IC50 = 0.24 μ M). GW6471 enhances the binding affini
GSK-2830371
(Catalog# : 1810292, Cas# :
1404456-53-6
)
GSK 2830371 is a WiP1 inhibitor. It inhibits cell growth and tumor growth in lymphoma
GENZ-882706
(Catalog# : 1810176, Cas# :
2070864-35-4
)
GENZ-882706 is a potent colony stimulating factor-1 receptor (CSF-1R) Inhibitor.
GDC-0575
(Catalog# : 189272, Cas# :
1196541-47-5
)
GDC-0575 (ARRY-575, RG7741) is a potent and selective CHK1 inhibitor with an IC50 of
GSK-626616
(Catalog# : 188241, Cas# :
1025821-33-3
)
GSK 626616 is a YAK3/DYRK3 kinase inhibitor. It is a chemoprotective agent for the po
GT 949
(Catalog# : 187182, Cas# :
460330-27-2
)
GT 949 is a selective EAAT2 positive allosteric modulator (EC50 = 0.26 nM). Enhances
GSK-J4 free base
(Catalog# : 187163, Cas# :
1373423-53-0
)
GSK-J4 is a cell permeable, potent and selective histone demethylase.
Gefapixant
(Catalog# : 187122, Cas# :
1015787-98-0
)
Gefapixant, also known as AF-219 or MK-7264, is a P2X3 receptor antagonist. Gefapixan
GLL398
(Catalog# : 185313, Cas# :
2077980-83-5
)
GLL398 is an Oral Selective Estrogen Receptor Downregulator.
Glecaprevir
(Catalog# : 185311, Cas# :
1365970-03-1
)
Glecaprevir, also known as ABT-493 and A-1282576, is a NS 3/4A inhibitor potentially
GW843682X
(Catalog# : 185292, Cas# :
660868-91-7
)
GW843682X is a selective inhibitor of polo-like kinase 1 (PLK1) and polo-like kinase
GNE-7915
(Catalog# : 18595, Cas# :
1351761-44-8
)
GNE-7915 is a potent LRRK2 kinase inhibitor.
GLPG1837
(Catalog# : 1842811, Cas# :
1654725-02-6
)
GLPG-1837, also known as ABBV-974, is a novel cystic fibrosis transmembrane conductan
GC376 sodium
(Catalog# : 184175, Cas# :
1416992-39-6
)
GC376 is a 3CLpro inhibitor (3C-like protease inhibitor).
GNF-6231
(Catalog# : 18494, Cas# :
1243245-18-2
)
GNF-6231 is a potent, selective, and orally bioavailable Porcupine inhibitor that blo
GSK-3326595
(Catalog# : 184316, Cas# :
1616392-22-3
)
GSK-3326595, also known as EPZ015938, is an orally active, potent and selective inhib
GIBH-130
(Catalog# : 18428, Cas# :
1252608-59-5
)
GIBH-130是一种神经炎症抑制剂。
GSK872
(Catalog# : 17101621, Cas# :
1346546-69-7
)
GSK872 is a a receptor interacting protein kinase-3 (RIP3) inhibitor. GSK872 inhibits
GSK2881078
(Catalog# : 1791316, Cas# :
1539314-06-1
)
GSK-2881078 is a selective androgen receptor modulator potentially for the treatment
GJ-103 sodium
(Catalog# : 1791116, Cas# :
1459687-96-7
)
GJ103 sodium salt is an active analog of the read-through compound GJ072.
GJ-103 free acid
(Catalog# : 1791115, Cas# :
1459687-89-8
)
GJ-103 is an active analog of the read-through compound GJ072. Chemical-induced read
10074-G5
(Catalog# : 1791112, Cas# :
413611-93-5
)
10074-G5 is a c-Myc/Max interaction inhibitor. 10074-G5, similarly to 10058-F4 (#F368
GW0742
(Catalog# : 1791110, Cas# :
317318-84-6
)
GW0742, also known as GW610742 and GW0742X is a PPARδ/β agonist. GW0742 Induces Ear
Givinostat HCl
(Catalog# : 17919, Cas# :
199657-29-9
)
Givinostat or gavinostat, aslo known as ITF2357, is a potent and orally active histon
Grazoprevir hydrate
(Catalog# : 1783018, Cas# :
1350462-55-3
)
Grazoprevir, also known as MK5172, is a drug approved for the treatment of hepatitis
GNE-3511
(Catalog# : 1781006, Cas# :
1496581-76-0
)
GNE-3511 is a potent and selective dual leucine zipper kinase (DLK, MAP3K12) inhibito
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
MTX115325
(Catalog# : 186264, Cas# :
2750895-97-5
)
MTX115325 is a potent, selective, brain-penetrant USP30 inhibitor with good drug-like
LY-3381916
(Catalog# : 193123, Cas# :
2166616-75-5
)
LY-3381916 is a potent, selective and brain penetrated inhibitor of IDO1 activity, bi
Opakalim
(Catalog# : 25193, Cas# :
2376397-93-0
)
Opakalim (BHV-7000) is an oral, small-molecule activator of Kv7.2/7.3 potassium chann
DS68591889
(Catalog# : 25158, Cas# :
2488609-21-6
)
DS68591889 (PTDSS1i) specifically inhibits PTDSS1, which catalyzes serine incorporati
CAY 10566
(Catalog# : 10403, Cas# :
944808-88-2
)
CAY 10566 is a potent selective SCD-1 inhibitor.
Cadefrecitinib (GLPG-3667)
(Catalog# : 20509, Cas# :
2308520-97-8
)
Cadefrecitinib (GLPG-3667) is an oral, small molecule inhibitor of the TYK2 kinase in
QBS10072S
(Catalog# : 25190, Cas# :
1802735-28-9
)
QBS10072S isa blood-brain-barrier (BBB) penetrative agent composed of a cytotoxic che
Dencatistat
(Catalog# : 25177, Cas# :
2377000-84-3
)
Dencatistat is an orally bioavailable, small molecule inhibitor of cytidine triphosph
DS-1001b
(Catalog# : 25178, Cas# :
1898207-64-1
)
DS-1001 is an oral brain-penetrant mutant IDH1 selective inhibitor.
Z57346765
(Catalog# : 25191, Cas# :
1016340-64-9
)
Z57346765 is a PGK1-specific inhibitor that reduces the activity of metabolic enzymes