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Inhibitors & Agonists
Angiogenesis
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Autophagy
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DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
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TGF-beta/Smad
Ubiquitin
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Amino Acids
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Bromides
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Name Index G
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Name Index G
GCN2iB
(Catalog# : 2071802, Cas# :
2183470-12-2
)
GCN2iB is an ATP-competitive GCN2 inhibitory compound with a better pharmacokinetic p
GRL0617
(Catalog# : 2071625, Cas# :
1093070-16-6
)
GRL0617 is a potent, selective and competitive noncovalent inhibitor of SARS PLPro. G
GS-441524
(Catalog# : 2071546, Cas# :
1191237-69-0
)
GS-441524 is a potent inhibitor of feline infectious peritonitis (FIP) virus with an
GSK3145095
(Catalog# : 2071533, Cas# :
1622849-43-7
)
GSK3145095 is a potent and orally active RIPK1 inhibitor (IC50 = 5 nM) with potential
GSK2894631A
(Catalog# : 2071528, Cas# :
2101626-26-8
)
GSK2894631A is a hematopoietic PGD synthase (HPGDS) inhibitor.
GSK8612
(Catalog# : 2071527, Cas# :
2361659-62-1
)
GSK8612 is a potent and highly selective TBK1 inhibitor. GSK8612 inhibited recombinan
GSK547
(Catalog# : 2071522)
GSK547 is a highly selective and potent inhibitor of RIP1 kinase that targets RIP1 in
GSK1016790A
(Catalog# : 2071511, Cas# :
942206-85-1
)
GSK1016790A, also known as GSK101, is a TRPV4 agonist that elicits calcium influx in
GNE-131
(Catalog# : 2071509, Cas# :
1629063-81-5
)
GNE-131 is a Potent and Selective hNaV1.7 Inhibitor (Na V1.7 IC50 = 3 nM) for the Tre
GW284543
(Catalog# : 2061310, Cas# :
790186-68-4
)
GW284543, also known as UNC10225170;, is a potent and selective MEK5 inhibitor with t
G-1
(Catalog# : 206103, Cas# :
881639-98-1
)
G-1 is a selective agonist for GPER. It acts by blocking tubulin polymerization.
Glumetinib
(Catalog# : 203401, Cas# :
1642581-63-2
)
Glumetinib, also known as SCC244, is a novel, potent and highly selective inhibitor o
GNE-2861
(Catalog# : 111892, Cas# :
1394121-05-1
)
GNE-2861 is a potent and exquisitely kinase-selective Group II PAK inhibitor (PAK4 Ki
GSK-199
(Catalog# : 193293, Cas# :
1549811-53-1
)
GSK199 is a selective PAD4 inhibitor with half-maximum inhibitory concentration (IC50
GS-626510
(Catalog# : 193221, Cas# :
1637770-13-8
)
GS-626510 is a potent BET family bromodomains inhibitor. It acts by targeting BRD2/3/
GSK2837808A
(Catalog# : 193194, Cas# :
1445879-21-9
)
GSK2837808A is a potent, selective lactate dehydrogenase A (LDHA) inhibitor (IC50 val
GSK-963
(Catalog# : 193185, Cas# :
2049868-46-2
)
GSK-963, also known as GSK'963 or GSK963, is a potent and selective inhibitor of
GNE-9605
(Catalog# : 192284, Cas# :
1536200-31-3
)
GNE-9605 is a highly potent, selective, and brain-penetrant aminopyrazole leucine-ric
GSK3004774
(Catalog# : 192281, Cas# :
2138814-32-9
)
GSK3004774 is a potent, nonabsorbable agonist of CaSR, with an pEC50 of 7.3, 6.6 and
GW-3965 HCl
(Catalog# : 192251, Cas# :
405911-17-3
)
GW-3965 is a liver X receptor agonist. GW3965 represses the production of pro-inflamm
GSK2334470
(Catalog# : 192224, Cas# :
1227911-45-6
)
GSK2334470 is a potent 3-phosphoinositide-dependent protein kinase (PDK1) inhibitor (
GSK269962 HCl
(Catalog# : 192201, Cas# :
2095432-71-4
)
GSK269962 is a selective ROCK inhibitor with IC50 values of 1.6 and 6 nM for ROCK-I a
GW-803430
(Catalog# : 192194, Cas# :
515141-51-2
)
GW-803430 is a potent, orally active and selective melanin-concentrating hormone rece
GNE-477
(Catalog# : 192181, Cas# :
1032754-81-6
)
GNE-477, a potent and efficacious dual PI3K/mTOR inhibitor.
GSKJ1
(Catalog# : 191255, Cas# :
1373422-53-7
)
GSKJ1 is a selective and potent histone demethylase inhibitor (GSK-J1) that has signi
GSK2643943A
(Catalog# : 191144, Cas# :
//
)
GSK2643943A is a potent USP20 inhibitor with IC50 = 160 nM.
GSK-2807
(Catalog# : 19185, Cas# :
2245255-65-4
)
GSK-2807 is a potent and selective, SAM-competitive inhibitor of SMYD3.
GNE-6640
(Catalog# : 1812291, Cas# :
2009273-67-8
)
GNE-6640 is a novel selective USP7 inhibitor, inducing tumor cell death. GNE-6640 enh
GSK1940029
(Catalog# : 1812102, Cas# :
1150701-66-8
)
GSK1940029, also known as SCD Inhibitor 1, is a SCD Inhibitor. GSK1940029 is a potent
GSK2814338
(Catalog# : 181241, Cas# :
1420367-28-7
)
GSK2814338, also known as Lp-PLA2 -IN-1, is a Lp-PLA2 inhibitor.
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Atebimetinib
(Catalog# : 25148, Cas# :
2669009-92-9
)
Atebimetinib (IMM-1-104) is an oral, small-molecule allosteric inhibitor of the MEK1
Acoramidis hydrochloride
(Catalog# : 24068, Cas# :
2242751-53-5
)
Acoramidis is an oral, potent, and highly selective small molecule transthyretin (TTR
Crelosidenib
(Catalog# : 24101, Cas# :
2230263-60-0
)
Crelosidenib is an isocitrate dehydrogenase 1 (IDH1) inhibitor.
LOXO-435
(Catalog# : 25080, Cas# :
2833703-74-3
)
LOXO-435 is a selective small molecule inhibitor of FGFR3. It is active against both
MAT2A-IN-9
(Catalog# : 25147, Cas# :
2439277-80-0
)
MAT2A-IN-9 (compound 167), a 2-oxoquinazoline derivative, is a potent MAT2A (methioni
Gridegalutamide
(Catalog# : 25138, Cas# :
2446928-30-7
)
Gridegalutamide, also known as BMS-986365 and CC-94676, is a heterobifunctional, firs
Chiauranib
(Catalog# : 25146, Cas# :
1256349-48-0
)
Chiauranib also known as orally available, small molecule inhibitor of select serine-
Atuzabrutinib
(Catalog# : 25145, Cas# :
1581714-49-9
)
Atuzabrutinib, also known as PRN 473, is a Bruton's tyrosine kinase inhibitor.
Andamertinib
(Catalog# : 25144, Cas# :
2254145-43-0
)
Andamertinib is an epidermal growth factor receptor tyrosine kinase inhibitor. It is
MEN-1703
(Catalog# : 25143, Cas# :
2769008-22-0
)