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DNA Damage
Epigenetics
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Immunology & Inflammation
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MAPK
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
Antibody-drug Conjugate/ADC Related
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Name Index G
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Name Index G
GNE-3511
(Catalog# : 1781006, Cas# :
1496581-76-0
)
GNE-3511 is a potent and selective dual leucine zipper kinase (DLK, MAP3K12) inhibito
GSK2193874
(Catalog# : 178914, Cas# :
1336960-13-4
)
GSK2193874 was identified as a selective, orally active TRPV4 blocker that inhibits C
GW4869
(Catalog# : 178912, Cas# :
6823-69-4
)
GW4869 (dihydrochloride hydrate) is a cell permeable, selective inhibitor of N-SMase
GSK2982772
(Catalog# : 178911, Cas# :
1622848-92-3
)
GSK2982772 is an ATP competitive eceptor-interacting protein-1 (RIP1) kinase inhibit
GSK180736A (GSK180736)
(Catalog# : 178901, Cas# :
817194-38-0
)
GSK180736A is potent and selective inhibitor of GRK2 with an IC50 of 0.77 M25 and >10
GSK2269557
(Catalog# : 2017883, Cas# :
1254036-77-5
)
GSK2269557,also known as GSK-2269557, is a potent and selective PI3K inhibitor.
GDC-0326
(Catalog# : 2017881, Cas# :
1282514-88-8
)
GDC-0326 is a potent and selective inhibitor of α-Isoform of Phosphoinositide 3-Kina
GSK-1521498
(Catalog# : 20178215, Cas# :
1007573-18-3
)
GSK-1521498 is a novel -Opioid receptor antagonist. It has been shown to attenuate re
GSK321
(Catalog# : 2017821, Cas# :
1816331-63-1
)
GSK321 is a potent and selective IDH1 mutant inhibitor. GSK321 potently inhibited int
GNE-272
(Catalog# : 20178121, Cas# :
1936428-93-1
)
GNE-272 is a potent and selective in Vivo Probe for the Bromodomains of CBP/EP300 (CB
Guanoclor
(Catalog# : 17030702, Cas# :
5001-32-1
)
Guanoclor is an antihypertensive drug.
GRA Ex-25
(Catalog# : 17030701, Cas# :
307983-31-9
)
GRA Ex-25 is an inhibitor of glucagon receptor. Inhibiting the interaction between gl
GTS-21
(Catalog# : 16123016, Cas# :
156223-05-1
)
GTS-21, also known as DMBX-A, is a derivative of the natural product anabaseine that
GSK6853 (GSK-6853)
(Catalog# : 16123015, Cas# :
1910124-24-1
)
GSK6853 is a potent (300 pM), soluble, cell active (20 nM), and highly selective inhi
GSK583
(Catalog# : 16123014, Cas# :
1346547-00-9
)
GSK583 is a Highly Potent and Selective Inhibitor of RIP2 Kinase (RIP2K bing IC50=5 n
GSK369796 Dihydrochloride
(Catalog# : 16123013, Cas# :
1010411-21-8
)
GSK369796, also known as N-tert-butylisoquine, is an anti-malaria drug candidate. GSK
GSK2801
(Catalog# : 16123012, Cas# :
1619994-68-1
)
GSK2801 is a A Selective Chemical Probe for BAZ2B/A bromodomains. BAZ2A/B belong to a
GSK-2256098
(Catalog# : 16123011, Cas# :
1224887-10-8
)
GSK2256098, also known as GTPL7939, is a focal adhesion kinase-1 (FAK) inhibitor with
GSK137647A
(Catalog# : 16123010, Cas# :
349085-82-1
)
GSK137647A is an agonist of the free fatty acid receptor 4 (FFA4/GPR120) with pEC50s
GSK0660
(Catalog# : 16123009, Cas# :
1014691-61-2
)
GSK0660 is a selective PPAR antagonist. GSK0660 differentially regulated 273 transcri
Go6983
(Catalog# : 16123008, Cas# :
133053-19-7
)
GO6983 is a potent protein kinase C (PKC) inhibitor. GO6893 displays cardioprotective
GNE-617
(Catalog# : 16123007, Cas# :
1362154-70-8
)
GNE-617 is a potent nicotinamide phosphoribosyltransferase (NAMPT) inhibitor with IC5
GlyH-101
(Catalog# : 16123006, Cas# :
328541-79-3
)
GlyH-101 is a CFTR inhibitor (cystic fibrosis transmembrane conductance regulator). G
GLPG-1690(ziritaxestat)
(Catalog# : 16123005, Cas# :
1628260-79-6
)
GLPG1690 is a selective autotaxin inhibitor discovered by Galapagos, with potential a
GDC-0853
(Catalog# : 16123004, Cas# :
1434048-34-6
)
GDC-0853 is orally available inhibitor of Bruton's tyrosine kinase (BTK) with potenti
GABOB (beta-hydroxy-GABA)
(Catalog# : 16122815, Cas# :
7013-05-0
)
GABOB, also known as -Amino--hydroxybutyric acid, -hydroxy--aminobutyric acid, -hydro
Gabexate mesylate
(Catalog# : 16122814, Cas# :
56974-61-9
)
Gabexate is a serine protease inhibitor which is used therapeutically (as gabexate me
Glasdegib (PF-04449913)
(Catalog# : 16122787, Cas# :
1095173-27-5
)
Glasdegib (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibit
Go6976
(Catalog# : 16122723, Cas# :
136194-77-9
)
Go6976 is a potent PKC inhibitor with IC50 of 7.9 nM, 2.3 nM, and 6.2 nM for PKC (Rat
GSK2292767
(Catalog# : 16122702, Cas# :
1254036-66-2
)
GSK2292767 is a potent and selective PI3K inhibitor.GSK2292767 is highly selective fo
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
----
NEKs
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
----
Methionine Adenosyltransferase (MAT)
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
----
GLP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
----
Reactive Oxygen Species(ROS)
----
SOD
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolic Enzyme/Protease
----
PPAR
----
Proteasome
----
P450
----
Caspase
----
HSP
----
HIV Protease
----
PDE
----
MMP
----
Factor Xa
----
γ-secretase
----
Phospholipase
----
DPP4
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
NADPH-oxidase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
FPTase
----
RAR/RXR
----
Acetyl-CoA Carboxylase
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Glutaminase
----
Ketohexokinase(KHK)
----
Lipase
----
Lactate dehydrogenase
----
Glyoxalase (GLO)
----
E1/E2/E3 Enzyme
----
PANK(pantothenate kinase)
----
Phosphoglycerate Dehydrogenase (PHGDH)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
----
CGRP-Receptor
----
TRP-Channel
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
----
Vps34
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
----
Notch
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
-- Nuclear Receptor
----
Androgen Receptor(AR)
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
DPTX-3186
(Catalog# : 26A010, Cas# :
3118994-80-9
)
DPTX3186, an orally administered small molecule condensate modulator (c-mod) inhibiti
Avasopasem manganese (GC-4419; M-40419)
(Catalog# : 25108, Cas# :
435327-40-5
)
Avasopasem manganese, also known as GC-4419; M 40419 and SC-72325A, is amimetic of th
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
Kartogenin ( KGN )
(Catalog# : 52215, Cas# :
4727-31-5
)
Kartogenin (KGN) is a synthetic small molecule that stimulates chondrogenic cellular
Imisopasem manganese ( M40403; GC4403 )
(Catalog# : 72602, Cas# :
218791-21-0
)
Imisopasem manganese ( M40403; GC4403 ) is a stable non-peptidyl mimetic of MnSOD tha
Apecotrep (BI 764198)
(Catalog# : 26A048, Cas# :
2311863-36-0
)
Apecotrep (BI 764198) is a potential first-in-class, oral, selective TRPC6 inhibitor.
Pantothenate kinase-IN-2
(Catalog# : 26A038, Cas# :
902614-04-4
)
Pantothenate kinase-IN-2 is a pantothenate kinase inhibitor with IC50 values of 92 nM
BH-30643
(Catalog# : 26A047, Cas# :
3062177-59-4
)
BH-30643 is a novel, orally available, non-covalent, macrocyclic, mutant selective OM
Gridegalutamide
(Catalog# : 26A044, Cas# :
2446929-86-6
)
gridegalutamide is an orally bioavailable androgen receptor (AR) degrader, with poten
BMS-986365 (Synonyms: CC-94676 )
(Catalog# : 25138, Cas# :
2446928-30-7
)
BMS-986365, also known as CC-94676, is an orally bioavailable androgen receptor (AR)