GSK2193874
Catalog No: 178914
CAS Number: 1336960-13-4
Purity: 98.0%
GSK2193874 was identified as a selective, orally active TRPV4 blocker that inhibits Ca(2+) influx through recombinant TRPV4 channels and native endothelial TRPV4 currents.
For research use only. We do not sell to patients.
Chemical Information
| Name | GSK2193874 |
|---|---|
| Iupac Chemical Name | 3-([1,4'-Bipiperidin]-1'-ylmethyl)-7-bromo-N-(1-phenylcyclopropyl)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxamide |
| Synonyms | GSK 2193874;GSK2193874 |
| Molecular Formula | C37H38BrF3N4O |
| Molecular Weight | 691.62 |
| Smile | N1(CCCCC1)C1CCN(CC1)CC=1C(=NC2=CC(=CC=C2C1C(=O)NC1(CC1)C1=CC=CC=C1)Br)C1=CC(=CC=C1)C(F)(F)F |
| InChiKey | UIVOZBSCHXCGPS-UHFFFAOYSA-N |
| InChi | InChI=1S/C37H38BrF3N4O/c38-28-12-13-30-32(23-28)42-34(25-8-7-11-27(22-25)37(39,40)41)31(24-44-20-14-29(15-21-44)45-18-5-2-6-19-45)33(30)35(46)43-36(16-17-36)26-9-3-1-4-10-26/h1,3-4,7-13,22-23,29H,2,5-6,14-21,24H2,(H,43,46) |
| CAS Number | 1336960-13-4 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98.0% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
