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GSK2193874

Catalog No: 178914
CAS Number: 1336960-13-4
Purity: 98.0% 

GSK2193874 was identified as a selective, orally active TRPV4 blocker that inhibits Ca(2+) influx through recombinant TRPV4 channels and native endothelial TRPV4 currents.
 

For research use only. We do not sell to patients.

Chemical Information

NameGSK2193874
Iupac Chemical Name3-([1,4'-Bipiperidin]-1'-ylmethyl)-7-bromo-N-(1-phenylcyclopropyl)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxamide 
SynonymsGSK 2193874;GSK2193874 
Molecular FormulaC37H38BrF3N4O 
Molecular Weight691.62 
SmileN1(CCCCC1)C1CCN(CC1)CC=1C(=NC2=CC(=CC=C2C1C(=O)NC1(CC1)C1=CC=CC=C1)Br)C1=CC(=CC=C1)C(F)(F)F
InChiKeyUIVOZBSCHXCGPS-UHFFFAOYSA-N
InChiInChI=1S/C37H38BrF3N4O/c38-28-12-13-30-32(23-28)42-34(25-8-7-11-27(22-25)37(39,40)41)31(24-44-20-14-29(15-21-44)45-18-5-2-6-19-45)33(30)35(46)43-36(16-17-36)26-9-3-1-4-10-26/h1,3-4,7-13,22-23,29H,2,5-6,14-21,24H2,(H,43,46)
CAS Number1336960-13-4
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Ordering Information

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Formulationoff-white solid 
Purity98.0% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

178914 - GSK2193874 | CAS 1336960-13-4

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