GlyH-101
Catalog No: 16123006
CAS Number: 328541-79-3
Purity: 98%
GlyH-101 is a CFTR inhibitor (cystic fibrosis transmembrane conductance regulator). GlyH-101 is a glycine hydrazide that has been shown to block CFTR channels. GlyH-101 blocked I(Cl.PKA) in a concentration- and voltage-dependent fashion (IC(50) at +100 mV=0.3 Â 1.5 M and at -100 mV=5.1 Â 1.3 M). GlyH-101 blocks the open pore of cardiac CFTR channels at an electrical distance of 0.15 Â 0.03 from the external membrane surface.
For research use only. We do not sell to patients.
Chemical Information
| Name | GlyH-101 |
|---|---|
| Iupac Chemical Name | GlyH-101 |
| Synonyms | GlyH101; GlyH 101 |
| Molecular Formula | C19H15Br2N3O3 |
| Molecular Weight | 493.15 |
| Smile | c1ccc2cc(ccc2c1)NCC(=O)N/N=C/c3cc(c(c(c3O)Br)O)Br |
| InChiKey | RMBDLOATEPYBSI-NUGSKGIGSA-N |
| InChi | InChI=1S/C19H15Br2N3O3/c20-15-8-13(18(26)17(21)19(15)27)9-23-24-16(25)10-22-14-6-5-11-3-1-2-4-12(11)7-14/h1-9,22,26-27H,10H2,(H,24,25)/b23-9+ |
| CAS Number | 328541-79-3 |
| MDL | MFCD01532954 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
