GNE-272
Catalog No: 20178121
CAS Number: 1936428-93-1
Purity: 98%
GNE-272 is a potent and selective in Vivo Probe for the Bromodomains of CBP/EP300 (CBP IC50 = 0.02 M, EP300 IC50 = 0.03 M, BRET IC50 = 0.41 M, BRD4(1) C50 = 13 M).
For research use only. We do not sell to patients.
Chemical Information
| Name | GNE-272 |
|---|---|
| Iupac Chemical Name | (S)-1-(3-((2-fluoro-4-(1-methyl-1H-pyrazol-4-yl)phenyl)amino)-1-(tetrahydrofuran-3-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl)ethan-1-one |
| Synonyms | GNE-272;GNE 272;GNE272 |
| Molecular Formula | C22H25FN6O2 |
| Molecular Weight | 424.4804 |
| Smile | FC1=C(C=CC(=C1)C=1C=NN(C1)C)NC1=NN(C2=C1CN(CC2)C(C)=O)[C@@H]2COCC2 |
| InChiKey | NKOJNOBJGYTLLZ-KRWDZBQOSA-N |
| InChi | InChI=1S/C22H25FN6O2/c1-14(30)28-7-5-21-18(12-28)22(26-29(21)17-6-8-31-13-17)25-20-4-3-15(9-19(20)23)16-10-24-27(2)11-16/h3-4,9-11,17H,5-8,12-13H2,1-2H3,(H,25,26)/t17-/m0/s1 |
| CAS Number | 1936428-93-1 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
