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Autophagy
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DNA Damage
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Immunology & Inflammation
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MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
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TGF-beta/Smad
Ubiquitin
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PROTAC
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Iodos
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
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Name Index D
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Name Index D
Doxapram
(Catalog# : 16122937, Cas# :
309-29-5
)
Doxapram is a respiratory stimulant. Administered intravenously, doxapram stimulates
Dobutamine HCl
(Catalog# : 16122936, Cas# :
34368-04-2
)
Dobutamine is a sympathomimetic drug used in the treatment of heart failure and cardi
DM1-SMe
(Catalog# : 16122935, Cas# :
138148-68-2
)
DM1-SMe is a potent maytansinoid microtubular inhibitor and an unconjugated DM1 as a
DM1-SMCC
(Catalog# : 16122934, Cas# :
1228105-51-8
)
DM1-SMCC is DM1 with a reactive linker SMCC, which can react with antibody to make an
Dimethylenastron
(Catalog# : 16122932, Cas# :
863774-58-7
)
Dimethylenastron is an inhibitor of mitotic motor kinesin Eg5 (IC50 = 200 nM). Dimeth
Dihydroethidium
(Catalog# : 16122931, Cas# :
104821-25-2
)
Dihydroethidium, also known as Hydroethidine and PD-MY 003, is a cell-permeable blue
Delamanid (OPC-67683)
(Catalog# : 16122930, Cas# :
681492-22-8
)
Delamanid, also known as OPC-67683, is a drug for the treatment of multi-drug-resista
Defactinib
(Catalog# : 16122929, Cas# :
1073160-26-5
)
Defactinib, also known as VS-6063 and PF04554878, is an orally bioavailable, small-mo
Debio-1347
(Catalog# : 16122928, Cas# :
1265229-25-1
)
Debio-1347, also known as FF284 and CH5183284, is an orally bioavailable inhibitor of
Darinaparsin
(Catalog# : 16122927, Cas# :
69819-86-9
)
Darinaparsin, also know as ZIO-101 is a small-molecule organic arsenical with potenti
Daclatasvir
(Catalog# : 16122926, Cas# :
1009119-64-5
)
Daclatasvir (USAN), also known as BMS-790052 and EBP-883 (trade name Daklinza), is NS
D-64131
(Catalog# : 16122925, Cas# :
74588-78-6
)
D-64131 is a potent and selective tubulin inhibitor. D-64131 inhibits tumor cell prol
Dalbavancin HCl
(Catalog# : 16122808, Cas# :
171500-79-1
)
Dalbavancin is a novel second-generation lipoglycopeptide antibiotic. It belongs to t
Dabrafenib mesylate
(Catalog# : 16122807, Cas# :
1195768-06-9
)
Dabrafenib mesylate, also known as GSK 2118436B, is a potent and orally active B-raf
Dolutegravir Sodium
(Catalog# : 16122764, Cas# :
1051375-19-9
)
Dolutegravir is a HIV integrase inhibitor with IC50 of 2.7 nM.Dolutegravir(S/GSK13495
DCVC
(Catalog# : 6111408, Cas# :
13419-46-0
)
DCVC inhibits pathogen-stimulated TNF- in human extra placental membranes in vitro.
Danirixin
(Catalog# : 16111111, Cas# :
954126-98-8
)
Danirixin is a small molecule, non-peptide, high affinity (IC50 for CXCL8 binding = 1
Defactinib
(Catalog# : 6111019, Cas# :
1345713-71-4
)
Defactinib(VS-6063, PF-04554878)
2,3-dimethoxybenzonitrile
(Catalog# : 6111003, Cas# :
5653-62-3
)
2,3-dimethoxybenzonitrile
10-Deacetyl-7-xylosyl paclitaxel
(Catalog# : 611946, Cas# :
90332-63-1
)
10-Deacetyl-7-xylosyl paclitaxel is a Paclitaxel derivative with improved pharmacolog
Debio 0932
(Catalog# : 611938, Cas# :
1061318-81-7
)
Debio 0932 ( CUDC-305 ) is a novel heat shock protein 90 (HSP90) inhibitor trong affi
DUBs-IN-3
(Catalog# : 611929, Cas# :
924296-17-3
)
DUBs-IN-3 is a potent deubiquitinase enzyme inhibitor with IC50s of 3.1 uM for USP8;
DUBs-IN-1
(Catalog# : 611928, Cas# :
924296-18-4
)
DUBs-IN-1 is a potent deubiquitinase enzyme inhibitor with IC50s of 18 uM/0.71 uM for
DMAT
(Catalog# : 611913, Cas# :
749234-11-5
)
DMAT is a potent and specific CK2 inhibitor with an IC50 of 0.13 uM.
Dovitinib
(Catalog# : 16071106, Cas# :
405169-16-6
)
Dovitinib, also known as TKI-258 or CHIR-258, is an orally bioavailable FGFR3 inhibit
Dasotraline
(Catalog# : 16071017, Cas# :
675126-05-3
)
Dasotraline, also known as SEP-225,289, is a serotonin-norepinephrine-dopamine reupta
DeBio-1143 (AT-406)
(Catalog# : 16070501, Cas# :
1071992-99-8
)
 DeBio-1143, also known as AT-406, ARRY-334543and SM-406, is an orally bioavaila
Danoprevir
(Catalog# : 16070107, Cas# :
850876-88-9
)
Danoprevir, also known as ITMN-191 and RG-7227, is under development by InterMune Inc
DAA-1106
(Catalog# : 16062205, Cas# :
220551-92-8
)
DAA-1106
Dehydro Amlodipine
(Catalog# : 16060803, Cas# :
113994-41-5
)
Dehydro Amlodipine
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Safusidenib
(Catalog# : 25149, Cas# :
1898206-17-1
)
Safusidenib, also known as DS-1001, is an oral isocitrate dehydrogenase [NADP] cytopl
HC-7366
(Catalog# : 25076, Cas# :
2803470-63-3
)
HC-7366 is a potent and selective activator of the general control nonderepressible 2
Dencatistat
(Catalog# : 25177, Cas# :
2377000-84-3
)
Dencatistat is an orally bioavailable, small molecule inhibitor of cytidine triphosph
Flavopiridol ( Alvocidib )
(Catalog# : 237071, Cas# :
146426-40-6
)
Alvocidib is a synthetic dihydroxyflavone that is 5,7-dihydroxyflavone which is subst
AG-270
(Catalog# : 25176, Cas# :
2201056-66-6
)
MAT2A Inhibitor AG-270 is an orally available small molecule inhibitor of methionine
AZD-5904
(Catalog# : 181121, Cas# :
618913-30-7
)
AZD5904 is a potent orally bioavailable MPO inhibitor. In preclinical studies, AZD590
ALT-007
(Catalog# : 25157, Cas# :
2035010-37-6
)
ALT-007 is an orally bioavailable SPT inhibitor that is more potent than myriocin, sa
Nizubaglustat ( Synonyms: AZ-3102 )
(Catalog# : 25175, Cas# :
1633666-49-5
)
Nizubaglustat (AZ-3102) is an oral small molecule which inhibits glucosylceramide syn
Catadegbrutinib (Synonyms: BGB-16673; BTK-IN-29)
(Catalog# : 25174, Cas# :
2736508-60-2
)
Anatibant (Synonyms: LF 16-0687; XY-2405)
(Catalog# : 25173, Cas# :
209733-45-9
)