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Membrane Transporter/Ion Channel
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Neuronal Signaling
NF-κB
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Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
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Name Index D
DDD100097
(Catalog# : 20307, Cas# :
1215012-74-0
)
DDD100097 is an inhibitor of Trypanosoma brucei N-myristoyltransferase (TbNMT) with m
Dimethyl carbate
(Catalog# : 20274, Cas# :
39589-98-5
)
Dimethyl carbate is an insect repellent. It can be prepared by the Diels–Alder reac
Delgocitinib(JTE-052)
(Catalog# : 20273, Cas# :
1263774-59-9
)
Delgocitinib, also known as LEO-124249 and JTE052, is a potent and selective JAK inhi
Dapaconazole
(Catalog# : 20272, Cas# :
1269726-67-1
)
Dapaconazole is an antifungal drug candidate. Phase II trials showed that Dapaconazol
Difelikefalin HCl
(Catalog# : 21922, Cas# :
2413256-25-2
)
Difelikefalin, also known CR-845; MR-13A-9; MR-13A9, is a novel and potent kappa opio
Daridorexant ( ACT541468 )
(Catalog# : 20265, Cas# :
1505484-82-1
)
Daridorexant is a dual orexin receptor antagonist (DORA) designed and developed for t
Difelikefalin
(Catalog# : 21257, Cas# :
1024828-77-0
)
Difelikefalin HCl is in stock.Difelikefalin, also known CR-845; MR-13A-9; MR-13A9, is
2,4-dimethoxy-6-methylnicotinonitrile
(Catalog# : 21255, Cas# :
1450662-05-1
)
2,4-dimethoxy-6-methylnicotinonitrile, is a key intermediate ofLirametostat ( CPI-120
DTHIB
(Catalog# : 21242, Cas# :
897326-30-6
)
DTHIB is a direct and selective heat shock factor 1 (HSF1) inhibitor with a Kd of 160
diABZI STING agonist-1 trihydrochloride
(Catalog# : 2112802, Cas# :
2138299-34-8
)
DS-6051B adipate
(Catalog# : 211153, Cas# :
1505515-69-4
)
DS-6051B is an orally available inhibitor of the receptor tyrosine kinases C-ros onco
DT-2216
(Catalog# : 20111802, Cas# :
2365172-42-3
)
DT2216 is a selective B-cell lymphoma extra large (BCL-XL) proteolysis-targeting chim
2,6-difluoro-3,5-dimethoxybenzeneamine
(Catalog# : 20103004, Cas# :
651734-54-2
)
2,6-difluoro-3,5-dimethoxybenzeneamine is a key intermeidate ofPemigatinib.1Kg~10Kg s
2,4-Dihydroxy-7-methoxy-2H,1,4-benzoxazin-3(4H)one
(Catalog# : 2071630, Cas# :
15893-52-4
)
Decoglurant
(Catalog# : 2071542, Cas# :
911115-16-7
)
Decoglurant, also known as Ro 4995819, is a negative allosteric modulator of the mGlu
Danicopan
(Catalog# : 2071535, Cas# :
1903768-17-1
)
Danicopan, aslo known as ACH-4471 and ACH-0144471, is a highly potent, orally active
DSP-2230
(Catalog# : 2071525, Cas# :
1233231-30-5
)
DSP-2230 is a selective Nav1.7/Nav1.8 blocker.
DSR-141562
(Catalog# : 20792, Cas# :
2007975-22-4
)
DSR-141562 is novel Phosphodiesterase 1 Inhibitor for the Treatment of Positive Sympt
1,4-diazaspiro[5.5]undecan-3-one
(Catalog# : 2071601, Cas# :
1547757-91-4
)
1,3-di(methoxymethoxy)benzene
(Catalog# : 202330, Cas# :
57234-29-4
)
5-(difluoromethyl)pyrazine-2-carboxylic acid
(Catalog# : 202326, Cas# :
1174321-06-2
)
1-(1,1-dimethyl-prop-2-ynyl)-4-methyl-piperazine
(Catalog# : 2062314, Cas# :
169194-80-3
)
2-(4-((2,6-dimethoxy-4-methyl-5-(3-(trifluoromethyl)phenoxy)quinolin-8-yl)amino)pentyl)isoindoline-1,3-dione
(Catalog# : 2062309, Cas# :
106635-87-4
)
1,3-Dibromo-2-(bromomethyl)benzene
(Catalog# : 2062308, Cas# :
93701-32-7
)
4-(3-(4-(4,5-dihydro-1H-imidazol-2-yl)-2-methoxy-3-nitrophenoxy)propyl)morpholine
(Catalog# : 2062021, Cas# :
1922200-81-4
)
3,5-dibromopyrazin-2-amine
(Catalog# : 2062016, Cas# :
24241-18-7
)
2-Amino-3,5-dibromopyrazine is used in the preparation of conjugated polymers for neu
2,6-DIMETHOXY-4-METHYL-5-[3-(TRIFLUOROMETHYL)PHENOXY]QUINOLIN-8-AMINE
(Catalog# : 2062013, Cas# :
106635-86-3
)
2,5-Dichloro-6-Methoxy-4-Methylquinoline
(Catalog# : 2062012, Cas# :
741233-61-4
)
2,3-Dichloro-4-hydroxypyridine
(Catalog# : 2062012, Cas# :
1174047-06-3
)
1,2-dichloro-2-phenyl-3-phthalimidopropane
(Catalog# : 2062007, Cas# :
85278-20-2
)
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Temozolomide
(Catalog# : 25209, Cas# :
85622-93-1
)
替莫唑胺是一种烷化剂。
ALT-007
(Catalog# : 25157, Cas# :
2035010-37-6
)
ALT-007 是一种口服生物可利用的 SPT 抑制剂,比多球菌素更有效,
Opakalim
(Catalog# : 25193, Cas# :
2376397-93-0
)
Opakalim(BHV-7000)是Kv7.2/7.3钾通道(KCNQ2/3)的口服小分子激活剂,
PF-06835919 ( MDK-1846 )
(Catalog# : 193264, Cas# :
2102501-84-6
)
MDK1846是一种强效的酮己糖激酶(KHK)抑制剂。
MK256
(Catalog# : 25208, Cas# :
2271348-04-8
)
MK256是一种新型CDK8抑制剂,通过下调STAT通路在急性髓系白血病(
NSD1 抑制剂 BT5
(Catalog# : 25207, Cas# :
2351225-46-0
)
BT5可有效抑制NSD1,与细胞中的SET结构域结合,并降低H3K36me2水平。
MA242 TFA
(Catalog# : 25206, Cas# :
1049704-18-8
)
MA242是一种MDM2和NFAT1双重抑制剂,可诱导MDM2自泛素化及降解,并抑
Dabogratinib ( TYRA-300 )
(Catalog# : 24073, Cas# :
2800223-30-5
)
Dabogratinib ( TYRA-300 )是一种口服选择性成纤维细胞生长因子受体3(
AF710B
(Catalog# : 25205, Cas# :
N/A
)
AF710B 是一种高效、选择性变构 M1 毒蕈碱和 σ1 受体激动剂。 AF710
MAT2A inhibitor 5
(Catalog# : 25204, Cas# :
2957874-18-7
)
MAT2A抑制剂5具有抑制MAT2A的高效力和对MTAP缺失的癌症细胞系的显著