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D-64131

Catalog No.: 16122925
Cas No.: 74588-78-6
Purity : 98% 
16122925 - D-64131 | CAS 74588-78-6

Catalog number : 16122925

CAS number : 74588-78-6

Molecular Formula : C16H13NO2 

Molecular Weight : 251.285 

Iupac Chemical Name : D-64131 

Smile : COc1ccc2c(c1)cc([nH]2)C(=O)c3ccccc3

InChiKey : ICMIJSRDISNKOC-UHFFFAOYSA-N

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SynonymsD 64131; D64131 
Molecular FormulaC16H13NO2 
Molecular Weight251.285 
Appearancecrystalline solid 
Purity98% 
SolubilitySoluble in DMSO 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
SmileCOc1ccc2c(c1)cc([nH]2)C(=O)c3ccccc3
InChiKeyICMIJSRDISNKOC-UHFFFAOYSA-N
InChiInChI=1S/C16H13NO2/c1-19-13-7-8-14-12(9-13)10-15(17-14)16(18)11-5-3-2-4-6-11/h2-10,17H,1H3
MDLMFCD04039791
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D-64131 is a potent and selective tubulin inhibitor. D-64131 inhibits tumor cell proliferation in vitro (IC50 = 74 nM). In xenograft experiments with the human amelanoic melanoma MEXF 989, D-64131 was highly active with treatment resulting in a growth delay of 23.4 days at 400 mg/kg. 

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