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MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
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Protein Tyrosine Kinase
Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
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Name Index D
1,1-Difluorocyclopropane-1-dibenzosuberyl Pyrazinium Bromide
(Catalog# : 2062005, Cas# :
312905-15-0
)
1,4-DPCA
(Catalog# : 204608, Cas# :
331830-20-7
)
1,4-DPCA is a potent and selective inhibitor of prolyl 4-hydroxylase.
Daprodustat (Synonyms: GSK1278863)
(Catalog# : 112596, Cas# :
960539-70-2
)
Daprodustat (Synonyms: GSK1278863) is an orally active hypoxia-inducible factor proly
Darapladib
(Catalog# : 193202, Cas# :
356057-34-6
)
Darapladib, also known as SB-480848, is a reversible lipoprotein-associated phospholi
D-609
(Catalog# : 19371, Cas# :
83373-60-8
)
D-609, also known as D-609 free, is a phospholipase C inhibitor potentially for the t
Degarelix acetate
(Catalog# : 192262, Cas# :
934246-14-7
)
Degarelix, also known as FE-200486 and ASP-3550, is a long-acting, synthetic peptide
DCC-2618 ( Ripretinib )
(Catalog# : 1811121, Cas# :
1442472-39-0
)
Ripretinib, also known as DCC-2618, is a potent, orally active and selective KIT/PDGF
Derazantinib
(Catalog# : 189273, Cas# :
1234356-69-4
)
Derazantinib, also known as ARQ-087, is an orally bioavailable inhibitor of the fibro
D-Lin-MC3-DMA
(Catalog# : 18942, Cas# :
1224606-06-7
)
D-Lin-MC3-DMA is the most potent cationic lipid that has been synthesized for Lipid n
Dipraglurant
(Catalog# : 187131, Cas# :
872363-17-2
)
Dipraglurant, aslo known as ADX-48621, is a negative allosteric modulator of the mGlu
Daun02
(Catalog# : 18793, Cas# :
290304-24-4
)
Daun02 is a Cell viability inhibitor and DNA synthisis inhibitor with IC50 values of
dBET1
(Catalog# : 186261, Cas# :
1799711-21-9
)
dBET1 is a competitive antagonist of BET bromodomains to hijack the Cereblon E3 ubiqu
2-D08
(Catalog# : 186231, Cas# :
144707-18-6
)
2-D08 is a synthetic flavone that inhibits sumoylation. 2-D08 showed anti-aggregatory
Daunorubicin free base
(Catalog# : 186212, Cas# :
20830-81-3
)
Daunorubicin exhibits cytotoxic activity through topoisomerase-mediated interaction w
DEL-22379
(Catalog# : 186155, Cas# :
181223-80-3
)
DEL-22379 is a potent and selective ERK Dimerization inhibitor.
Delafloxacin
(Catalog# : 18612, Cas# :
189279-58-1
)
Delafloxacin, also known as ABT-492, RX-3341 and WQ-3034, is a non-zwitterionic fluor
Delpazolid
(Catalog# : 18611, Cas# :
1219707-39-7
)
Delpazolid, also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone.
Desidustat
(Catalog# : 185231, Cas# :
1616690-16-4
)
Desidustat is an antianaemic drug candidate.
Dovitinib lactate
(Catalog# : 18575, Cas# :
915769-50-5
)
Dovitinib, also known as TKI-258 or CHIR-258, is an orally bioavailable FGFR3 inhibit
Defensamide
(Catalog# : 184212, Cas# :
1104874-94-3
)
Defensamide,也被称为MHP和甲基己酰酪氨酸,是鞘氨醇激酶(SPHK1)的激
2-(4-(((2,4-dimethylbenzoyl)oxy)methyl)phenyl)acetic acid
(Catalog# : 183215, Cas# :
2097334-16-0
)
2-(4-(((2,4-dimethylbenzoyl)oxy)methyl)phenyl)acetic acid是一种药物中间体。
DCG04
(Catalog# : 179813, Cas# :
314263-42-8
)
DCG04 is a multivalent ligand for the mannose-6-phosphate receptor for endolysosomal
3,5-Dichloro-N-[(1,1-dimethylethoxy)carbonyl]-L-tyrosine methyl ester
(Catalog# : 178222, Cas# :
261926-09-4
)
<span style="color:#333333;font-family:"font-size:14px;background-color:
2,6-dibromophenylacetonitrile
(Catalog# : 1781502, Cas# :
67197-53-9
)
2-(2,6-dibroMophenyl)acetonitrile is an important building blocks in the organic synt
Danusertib
(Catalog# : 1781107, Cas# :
827318-97-8
)
Danusertib, also known as PHA-739358, is a small-molecule 3-aminopyrazole derivative
6-(4,5-dihydro-1H-imidazol-2-yl)-2-methoxy-3-[3-(morpholin-4-yl)propoxy]aniline
(Catalog# : 2017080116, Cas# :
1032571-01-9
)
6-(4,5-dihydro-1H-imidazol-2-yl)-2-methoxy-3-(3-morpholin-4-ylpropoxy)aniline
Dobutamine HCl
(Catalog# : 17030803, Cas# :
49745-95-1
)
Dobutamine is a sympathomimetic drug used in the treatment of heart failure and cardi
Defactinib
(Catalog# : 120111, Cas# :
1073154-85-4
)
Defactinib is a potent FAK phosphorylation inhibitor; overcomes YB-1Cmediated paclita
Davercin
(Catalog# : 17030310, Cas# :
55224-05-0
)
Davercin, also known as Erythromycin Cyclocarbonate, is a bacteriostatic antibiotic m
Danshensu
(Catalog# : 17021315, Cas# :
76822-21-4
)
Danshensu, a herbal preparation used in traditional Chinese medicine, possesses poten
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Dabogratinib ( TYRA-300 )
(Catalog# : 24073, Cas# :
2800223-30-5
)
Dabogratinib ( TYRA-300 ) is an Oral Selective FGFR3 Inhibitor (IC50 = 11 nM) for the
AF710B
(Catalog# : 25205, Cas# :
N/A
)
AF710B is a highly selective and potent allosteric agonist for M1 muscarinic and σ1
MAT2A inhibitor 5
(Catalog# : 25204, Cas# :
2957874-18-7
)
MAT2A inhibitor 5 has a high potency for inhibiting MAT2A and a remarkable selectivit
(Rac)-AF710B
(Catalog# : 24083, Cas# :
1235733-73-9
)
AF-710B is an agonist of sigma and M1 muscarinic receptors; AF710B is an enantiomer o
Flurpiridaz-nonradiolabeled
(Catalog# : 25203, Cas# :
863888-33-9
)
Flurpiridazis a promising novel cardiac PET imaging tracer formed by the radiolabelin
Flurpiridaz-Precursor
(Catalog# : 25202, Cas# :
863888-32-8
)
Flurpiridaz-Precursor in stock.
KL1333
(Catalog# : 25201, Cas# :
1800405-30-4
)
KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinon
Palupiprant ( E7046 )
(Catalog# : 24055, Cas# :
1369489-71-3
)
E7046 is a potent and selective antagonist of the type 4 prostaglandin E2 (PGE2) rece
Oveporexton ( TAK-861 )
(Catalog# : 25194, Cas# :
2460722-04-5
)
Oveporexton isan oral small molecule selective orexin type-2 receptor (OX2R) agonist.
VT-3989
(Catalog# : 25200, Cas# :
2506273-81-8
)
VT3989, a first-in-class potent oral TEAD palmitoylation inhibitor, disrupts YAP tran