Welcome to Sun-shine chemical
+86-17702719238 sales@sun-shinechem.com

Defactinib

Catalog No: 16122929
CAS Number: 1073160-26-5
Purity: 98% 

Defactinib, also known as VS-6063 and PF04554878, is an orally bioavailable, small-molecule focal adhesion kinase (FAK) inhibitor with potential antiangiogenic and antineoplastic activities. Defactinib inhibits FAK, which may prevent the integrin-mediated activation of several downstream signal transduction pathways, including those involving RAS/MEK/ERK and PI3K/Akt, thus inhibiting tumor cell migration, proliferation, survival, and tumor angiogenesis. 

For research use only. We do not sell to patients.

Chemical Information

NameDefactinib
Iupac Chemical Name1073160-26-5 
SynonymsDefactinib hydrochloride; Defactinib HCl; VS6063; VS 6063; VS-6063; PF04554878; PF-04554878; PF 04554878; PF4554878; PF-4554878; PF4554878 
Molecular FormulaC20H22ClF3N8O3S 
Molecular Weight546.9542 
InChiKey
InChi
CAS Number1073160-26-5
Related CAS

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
BulkEnquiryEnquiryEnquiry
Request Bulk Quote Download MSDS Tel : +86-177 0271 9238   Email : sales@sun-shinechem.com
Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

16122929 - Defactinib | CAS 1073160-26-5

Quick Order

Change