DCVC inhibits pathogen-stimulated TNF- in human extra placental membranes in vitro.
DCVC inhibits pathogen stimulated cytokine release from tissue punch cultures. DCVC (5-50 M) significantly inhibits LTA-, LPS-, and GBS-stimulated cytokine release from tissue cultures as early as 4 h (P 0.05). In contrast, TCA (up to 500 M) does not inhibit LTA-stimulated cytokine release from tissue punches. DCVC effects on LTA-stimulated and LPS-stimulated TNF- release from tissue punch cultures of extraplacental membranes. DCVC effects on GBS-stimulated release of pro-inflammatory cytokines from extraplacental membranes in transwell cultures.
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| Name | DCVC |
|---|---|
| Iupac Chemical Name | DCVC |
| Synonyms | S-[(1E)-1,2-dichloroethenyl]--L-cysteine |
| Molecular Formula | C5H7Cl2NO2S |
| Molecular Weight | 216.09 |
| Smile | C([C@@H](C(=O)O)N)S/C(=C\Cl)/Cl |
| InChiKey | PJIHCWJOTSJIPQ-PEQLYWQKSA-N |
| InChi | InChI=1S/C5H7Cl2NO2S/c6-1-4(7)11-2-3(8)5(9)10/h1,3H,2,8H2,(H,9,10)/b4-1-/t3-/m0/s1 |
| CAS Number | 13419-46-0 |
| MDL | MFCD00870277 |
| Related CAS |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |