1,4-DPCA
1,4-DPCA is a potent and selective inhibitor of prolyl 4-hydroxylase.
For research use only. We do not sell to patients.
Chemical Information
| Name | 1,4-DPCA |
|---|---|
| Iupac Chemical Name | 4-oxo-1,4-dihydro-1,10-phenanthroline-3-carboxylic acid |
| Synonyms | 1,4-DPCA; 1,4 DPCA; 1,4DPCA; |
| Molecular Formula | C13H8N2O3 |
| Molecular Weight | 240.218 |
| Smile | O=C(C(C(O)=O)=CN1)C2=C1C3=C(C=C2)C=CC=N3 |
| InChiKey | XZZHOJONZJQARN-UHFFFAOYSA-N |
| InChi | InChI=1S/C13H8N2O3/c16-12-8-4-3-7-2-1-5-14-10(7)11(8)15-6-9(12)13(17)18/h1-6H,(H,15,16)(H,17,18) |
| CAS Number | 331830-20-7 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% Min. |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
| Targets | |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
1: Zhang Y, Strehin I, Bedelbaeva K, Gourevitch D, Clark L, Leferovich J, Messersmith PB, Heber-Katz E. Drug-induced regeneration in adult mice. Sci Transl Med. 2015 Jun 3;7(290):290ra92. doi: 10.1126/scitranslmed.3010228. PubMed PMID: 26041709; PubMed Central PMCID: PMC4687906.
2: Xiong G, Deng L, Zhu J, Rychahou PG, Xu R. Prolyl-4-hydroxylase α subunit 2 promotes breast cancer progression and metastasis by regulating collagen deposition. BMC Cancer. 2014 Jan 2;14:1. doi: 10.1186/1471-2407-14-1. PubMed PMID: 24383403; PubMed Central PMCID: PMC3880410.
3: Love RJ, Jones KS. Transient inhibition of connective tissue infiltration and collagen deposition into porous poly(lactic-co-glycolic acid) discs. J Biomed Mater Res A. 2013 Dec;101(12):3599-606. doi: 10.1002/jbm.a.34648. Epub 2013 Jun 14. PubMed PMID: 23766241.
Chemical Structure
