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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
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Other Azoles
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On Sale
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
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Custom Synthesis
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Name Index C
Ca2+ channel agonist 1
(Catalog# : 611918, Cas# :
1402821-24-2
)
Ca2+ channel agonist 1 is a N-type Ca2+ channel activity agonist, with EC50 of 14.23
CX-4945 sodium salt
(Catalog# : 611912, Cas# :
1309357-15-0
)
CX-4945 (Silmitasertib) sodium salt is a potent and selective ATP-competitive small m
CAL-130 Racemate
(Catalog# : 611824, Cas# :
474012-90-3
)
CAL-130 racemate is a novel phosphoinositide 3-kinase (PI3K) inhibitor. It is reporte
CAL-130 Hydrochloride
(Catalog# : 611823, Cas# :
1431697-78-7
)
CAL-130 Hcl is a novel phosphoinositide 3-kinase (PI3K) inhibitor. It is reported tha
CAL-130
(Catalog# : 611822, Cas# :
1431697-74-3
)
CAL-130 is a novel phosphoinositide 3-kinase (PI3K) inhibitor. It is reported that co
Compound 401
(Catalog# : 611816, Cas# :
168425-64-7
)
Compound 401 is a synthetic inhibitor of DNA-PK (IC50 = 0.28 M) that also targets mTO
CC-115 hydrochloride
(Catalog# : 611815, Cas# :
1300118-55-1
)
CC-115 hydrochloride is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM). CC-115 shows go
3 CAI
(Catalog# : 611801, Cas# :
28755-03-5
)
3CAI is a potent allosteric and specific AKT inhibitor, which exerts efficacy in vitr
Chrysophanic acid
(Catalog# : 161009017, Cas# :
481-74-3
)
Chrysophanic acid preferentially blocked proliferation in SNU-C5 cells but not in oth
CAY10505
(Catalog# : 160926016, Cas# :
1218777-13-9
)
CAY10505 is a phosphatidylinositol 3-kinase- inhibitor , was found to significantly i
CH5132799 (PA-799)
(Catalog# : 160926015, Cas# :
1007207-67-1
)
CH5132799, also known as PA-799, is a novel class I PI3K inhibitor, which exhibited a
CCT245737
(Catalog# : 16090101, Cas# :
1489389-18-5
)
CCT245737(CCT-245737, CAS 1489389-18-5) is the first orally active, clinical developm
CWHM-12
(Catalog# : 16071407, Cas# :
1564286-55-0
)
vitro ligand-binding assays, with somewhat less potency against v5 than against the o
CMK
(Catalog# : 16071401, Cas# :
821794-90-5
)
CMK
Copanlisib
(Catalog# : 16070917, Cas# :
1032568-63-0
)
Copanlisib, also known as BAY 80-6946, is a phosphoinositide 3-kinase (PI3K) inhibito
CCT244747
(Catalog# : 16070913, Cas# :
1404095-34-6
)
CCT244747 is a novel potent, highly selective, orally active ATP-competitive CHK1 inh
CP-673451
(Catalog# : 16070704, Cas# :
343787-29-1
)
CP-673451 is a selective inhibitor of PDGFR/ with IC50 of 10 nM/1 nM in cell-free ass
CHIR-99021
(Catalog# : 16062904, Cas# :
252917-06-9
)
CHIR-99021, also known as CT99021, is a glycogen synthase kinase 3 (GSK3) inhibitor t
CA-074
(Catalog# : 16062115, Cas# :
134448-10-5
)
CA-074
CF-102
(Catalog# : 16053104, Cas# :
163042-96-4
)
CF-102, also known as 2-Cl-IB-MECA, is an orally bioavailable, synthetic, highly sele
CHIR-090
(Catalog# : SSC65304, Cas# :
728865-23-4
)
CHIR-090 is a potent LpxC inhibitor, displays two-step time-dependent inhibition and
4-cyclopropylphenylacetic acid
(Catalog# : 032509, Cas# :
40641-90-5
)
Coming soon!
2-Chloro-3-fluoro-4-(trifluoromethyl)pyridine
(Catalog# : 032506, Cas# :
628692-22-8
)
Coming soon!
CEP-1347
(Catalog# : 032402, Cas# :
156177-65-0
)
Coming soon!
CPI-203
(Catalog# : 030201, Cas# :
1446144-04-2
)
CPI 203 is a novel potent, selective and cell permeable inhibitor of the bromodomain
CL-387785
(Catalog# : 022202, Cas# :
194423-06-8
)
CL-387785 is an irreversible inhibitor of EGFR with IC50 of 370+/-120 pM; is able to
CC-223
(Catalog# : 021802, Cas# :
1228013-30-6
)
CC-223 is a potent mTOR kinase inhibitor (IC50=16 nM), with >150-fold sensitivity
CJ-023423
(Catalog# : 012601, Cas# :
415903-37-6
)
CJ-023423 is a novel, potent and selective prostaglandin EP4 receptor antagonist with
CC-115
(Catalog# : 012004, Cas# :
1228013-15-7
)
CC-115 is a dual inhibitor of DNA-dependent protein kinase and mammalian target of ra
CB-5083
(Catalog# : 012002, Cas# :
1542705-92-9
)
CB-5083 is a novel first in class, potent orally bio-available p97 inhibitor that dis
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
PLX8394
(Catalog# : 20613, Cas# :
1393466-87-9
)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
Zelasudil
(Catalog# : 24014, Cas# :
2365193-22-0
)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
Ziftomenib ( KO-539 )
(Catalog# : 24013, Cas# :
2134675-36-6
)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
Zunsemetinib
(Catalog# : 24012, Cas# :
1640282-42-3
)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
Zongertinib
(Catalog# : 24011, Cas# :
2728667-27-2
)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
Zasocitinib
(Catalog# : 24010, Cas# :
2272904-53-5
)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
RNK-05047
(Catalog# : 24008, Cas# :
2503036-46-0
)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
Asengeprast (FT011)
(Catalog# : 24009, Cas# :
1001288-58-9
)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
ERAS-801 ( JGK-068S )
(Catalog# : 20635, Cas# :
2490431-16-6
)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
T-1095
(Catalog# : 24004, Cas# :
209746-59-8
)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).