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Autophagy
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GPCR & G Protein
Immunology & Inflammation
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MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
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Proteases
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
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Name Index C
CCG215022
(Catalog# : 16122914, Cas# :
1813527-81-9
)
CCG215022 is a potent GRK2 and GRK5 inhibitor. CCG215022 exhibited nanomolar IC50 val
CB-839
(Catalog# : 16122913, Cas# :
1439399-58-2
)
CB-839 an is orally bioavailable inhibitor of glutaminase, with potential antineoplas
CAY10683
(Catalog# : 16122912, Cas# :
1477949-42-0
)
CAY10683, also known as Santacruzamate A, is a potent and selective histone deacetyla
Cardiogenol C HCl
(Catalog# : 16122911, Cas# :
1049741-55-0
)
Cardiogenol C is a diaminopyrimidine compound that induces the differentiation of MHC
Capromorelin tartrate
(Catalog# : 16122910, Cas# :
193273-69-7
)
Capromorelin, also known as CP-424,391, is a growth hormone secretagogue and ghrelin
Canertinib
(Catalog# : 16122909, Cas# :
289499-45-2
)
Canertinib dihydrochloride is the hydrochloride salt of an orally bio-available quina
Camostat Mesilate
(Catalog# : 16122806, Cas# :
59721-29-8
)
Camostat Mesilate, also known as FOY 305, is a serine protease inhibitor. Serine prot
CPI-0610
(Catalog# : 16122738, Cas# :
1380087-89-7
)
CPI-0610 is a potent and selective benzoisoxazoloazepine BET bromodomain inhibitor an
CPI-637
(Catalog# : 16122737, Cas# :
1884712-47-3
)
CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibit
CeMMEC13
(Catalog# : 6111701, Cas# :
1790895-25-8
)
CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF
CB1-IN-1
(Catalog# : 6111108, Cas# :
1429239-98-4
)
CB1-IN-1 is a peripherally restricted CB1R antagonist, with Ki of 0.3 nM and 21 nM fo
Coelenterazine
(Catalog# : 6111016, Cas# :
55779-48-1
)
Coelenterazine
1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine
(Catalog# : 61110004, Cas# :
1228780-72-0
)
1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine
CC0651
(Catalog# : 611933, Cas# :
1319207-44-7
)
CC0651 is an allosteric inhibitor of the human cdc34 ubiquitin-conjugating enzyme tha
CDKI-73
(Catalog# : 611920, Cas# :
1421693-22-2
)
CDKI-73 is a potent CDK9 inhibitor with Ki of 4 nM; shows selective toxicity to CLL c
CDK9-IN-6
(Catalog# : 611919, Cas# :
1391855-95-0
)
CDK9-IN-6 is a CDK9 inhibitor, refers to Example 399 in WO 2012101062 A1
Ca2+ channel agonist 1
(Catalog# : 611918, Cas# :
1402821-24-2
)
Ca2+ channel agonist 1 is a N-type Ca2+ channel activity agonist, with EC50 of 14.23
CX-4945 sodium salt
(Catalog# : 611912, Cas# :
1309357-15-0
)
CX-4945 (Silmitasertib) sodium salt is a potent and selective ATP-competitive small m
CAL-130 Racemate
(Catalog# : 611824, Cas# :
474012-90-3
)
CAL-130 racemate is a novel phosphoinositide 3-kinase (PI3K) inhibitor. It is reporte
CAL-130 Hydrochloride
(Catalog# : 611823, Cas# :
1431697-78-7
)
CAL-130 Hcl is a novel phosphoinositide 3-kinase (PI3K) inhibitor. It is reported tha
CAL-130
(Catalog# : 611822, Cas# :
1431697-74-3
)
CAL-130 is a novel phosphoinositide 3-kinase (PI3K) inhibitor. It is reported that co
Compound 401
(Catalog# : 611816, Cas# :
168425-64-7
)
Compound 401 is a synthetic inhibitor of DNA-PK (IC50 = 0.28 M) that also targets mTO
CC-115 hydrochloride
(Catalog# : 611815, Cas# :
1300118-55-1
)
CC-115 hydrochloride is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM). CC-115 shows go
3 CAI
(Catalog# : 611801, Cas# :
28755-03-5
)
3CAI is a potent allosteric and specific AKT inhibitor, which exerts efficacy in vitr
Chrysophanic acid
(Catalog# : 161009017, Cas# :
481-74-3
)
Chrysophanic acid preferentially blocked proliferation in SNU-C5 cells but not in oth
CAY10505
(Catalog# : 160926016, Cas# :
1218777-13-9
)
CAY10505 is a phosphatidylinositol 3-kinase- inhibitor , was found to significantly i
CH5132799 (PA-799)
(Catalog# : 160926015, Cas# :
1007207-67-1
)
CH5132799, also known as PA-799, is a novel class I PI3K inhibitor, which exhibited a
CCT245737
(Catalog# : 16090101, Cas# :
1489389-18-5
)
CCT245737(CCT-245737, CAS 1489389-18-5) is the first orally active, clinical developm
CWHM-12
(Catalog# : 16071407, Cas# :
1564286-55-0
)
vitro ligand-binding assays, with somewhat less potency against v5 than against the o
CMK
(Catalog# : 16071401, Cas# :
821794-90-5
)
CMK
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Dabogratinib ( TYRA-300 )
(Catalog# : 24073, Cas# :
2800223-30-5
)
Dabogratinib ( TYRA-300 ) is an Oral Selective FGFR3 Inhibitor (IC50 = 11 nM) for the
AF710B
(Catalog# : 25205, Cas# :
N/A
)
AF710B is a highly selective and potent allosteric agonist for M1 muscarinic and σ1
MAT2A inhibitor 5
(Catalog# : 25204, Cas# :
2957874-18-7
)
MAT2A inhibitor 5 has a high potency for inhibiting MAT2A and a remarkable selectivit
(Rac)-AF710B
(Catalog# : 24083, Cas# :
1235733-73-9
)
AF-710B is an agonist of sigma and M1 muscarinic receptors; AF710B is an enantiomer o
Flurpiridaz-nonradiolabeled
(Catalog# : 25203, Cas# :
863888-33-9
)
Flurpiridazis a promising novel cardiac PET imaging tracer formed by the radiolabelin
Flurpiridaz-Precursor
(Catalog# : 25202, Cas# :
863888-32-8
)
Flurpiridaz-Precursor in stock.
KL1333
(Catalog# : 25201, Cas# :
1800405-30-4
)
KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinon
Palupiprant ( E7046 )
(Catalog# : 24055, Cas# :
1369489-71-3
)
E7046 is a potent and selective antagonist of the type 4 prostaglandin E2 (PGE2) rece
Oveporexton ( TAK-861 )
(Catalog# : 25194, Cas# :
2460722-04-5
)
Oveporexton isan oral small molecule selective orexin type-2 receptor (OX2R) agonist.
VT-3989
(Catalog# : 25200, Cas# :
2506273-81-8
)
VT3989, a first-in-class potent oral TEAD palmitoylation inhibitor, disrupts YAP tran