Claziprotamidum ( Claziprotamide ; BBP-671 )
Catalog No: 26A040
CAS Number: 2361124-03-8
Purity: ≧98.0%
Claziprotamidum ( Claziprotamide ; BBP-671 ) is a potent, orally active, and blood-brain barrier-permeable pan-pantothenate kinase (PanK) activator, serving as a positive allosteric modulator (PAM) of PanK1 and PanK3 isoforms. It enhances Coenzyme A (CoA) biosynthesis, making it a valuable research tool for treating metabolic disorders like pantothenate kinase-associated neurodegeneration (PKAN) and propionic acidemia.
For research use only. We do not sell to patients.
Chemical Information
| Name | Claziprotamidum ( Claziprotamide ; BBP-671 ) |
|---|---|
| Iupac Chemical Name | 1-(4-(6-chloropyridazin-3-yl)piperazin-1-yl)-2-(4-cyclopropyl-3-fluorophenyl)ethan-1-one |
| Synonyms | Claziprotamidum ; Claziprotamide ; BBP-671 ; BBP 671 ; BBP671 |
| Molecular Formula | C19H20ClFN4O |
| Molecular Weight | 374.1 |
| Smile | O=C(N1CCN(C2=NN=C(Cl)C=C2)CC1)CC3=CC=C(C4CC4)C(F)=C3 |
| InChiKey | GGZFNPBICDFCKG-UHFFFAOYSA-N |
| InChi | InChI=1S/C19H20ClFN4O/c20-17-5-6-18(23-22-17)24-7-9-25(10-8-24)19(26)12-13-1-4-15(14-2-3-14)16(21)11-13/h1,4-6,11,14H,2-3,7-10,12H2 |
| CAS Number | 2361124-03-8 |
| Related CAS | 2361124-03-8 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
