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Angiogenesis
Anti-infection
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Autophagy
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DNA Damage
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GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Name Index C
CA-4948
(Catalog# : 1811292, Cas# :
1801343-74-7
)
CA-4948 is a bioactive chemical.
CCT129202
(Catalog# : 1810291, Cas# :
942947-93-5
)
CCT129202 is an inhibitor of Aurora kinase activity and displays a favorable antineop
CBM 301940
(Catalog# : 1810232, Cas# :
902146-11-6
)
CBM 301940 is a potent malonyl-CoA decarboxylase inhibitor that is orally bioavailabl
CID16020046
(Catalog# : 1810225, Cas# :
834903-43-4
)
CID16020046 is a selective GPR55 inverse agonist.
10-Cl-BBQ
(Catalog# : 1810161, Cas# :
23982-76-5
)
10-Cl-BBQ is an aryl hydrocarbon receptor (AhR) ligand.
CGP-71683A HCl
(Catalog# : 18792, Cas# :
192322-50-2
)
CGP 71683A is a potent and highly selective non-peptide antagonist of the NPY Y(5) re
Carumonam Sodium
(Catalog# : 18752, Cas# :
86832-68-0
)
Carumonam Sodium, also known as Amasulin and AMA-1080, is a monobactam, penicillin bi
CEP-40783
(Catalog# : 186281, Cas# :
1437321-24-8
)
CEP-40783, also known as RXDX-106, is a potent, selective and orally available inhibi
CD437
(Catalog# : 185316, Cas# :
125316-60-1
)
CD437 is a synthetic retinoid that is an RARγ-selective agonist.
CB-1158
(Catalog# : 185315, Cas# :
1345810-21-0
)
CB-1158, also known as INCB01158, is a potent arginase inhibitor.
Cilomilast
(Catalog# : 185291, Cas# :
153259-65-5
)
Cilomilast (Ariflo, SB-207,499) is a drug which was developed for the treatment of re
CNX-1351
(Catalog# : 185174, Cas# :
1276105-89-5
)
CNX-1351 is a selective covalent Inhibitor of PI3Kα.
CGP60474
(Catalog# : 185171, Cas# :
164658-13-3
)
CGP60474 is a potent dual cdk1/cdk2 inhibitor (IC50 values are 20 and 50 nM, respecti
COH29
(Catalog# : 184127, Cas# :
1190932-38-7
)
COH29 is an orally available, aromatically substituted thiazole and inhibitor of the
CIL56
(Catalog# : 18491, Cas# :
300802-28-2
)
CIL56 is a YAP1 inhibitor. It acts by inducing non-apoptotic cell death, triggering c
Casopitant mesylate
(Catalog# : 18444, Cas# :
414910-30-8
)
Casopitant mesylate is the mesylate salt of a centrally-acting neurokinin 1 (NK1) rec
COTI-2
(Catalog# : 184320, Cas# :
1039455-84-9
)
COTI-2 is an P53 gene modulator and AKT2 inhibitor. OTI-2 is active against multiple
CBL0137
(Catalog# : 184319, Cas# :
314761-14-3
)
CBL0137 activates p53 and inhibits NF-kB. It also inhibits the group protein molecula
CPI-444
(Catalog# : 18439, Cas# :
1202402-40-1
)
CPI-444, also known as V81444, is an orally administered antagonist of the adenosine
CCG-203971
(Catalog# : 18437, Cas# :
1443437-74-8
)
CCG-203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (I
CP-376395游离
(Catalog# : 184213, Cas# :
175140-00-8
)
CP-376395是一种CRF1的选择性拮抗剂。
Copanlisib HCI
(Catalog# : 18351, Cas# :
1402152-13-9
)
Copanlisib also known as BAY 80-6946, is a potent phosphoinositide 3-kinase (PI3K) in
CB-03-01
(Catalog# : 1712153, Cas# :
19608-29-8
)
CB-03-01,也被称为cortexolone 17alpha -丙酸,是一种局部和外围选择性
Cenicriviroc ( TAK-652 )
(Catalog# : S510902, Cas# :
497223-25-3
)
Cenicriviroc ( TAK-652, TBR-652) is an experimental drug candidate for the treatment
CHIR99021 HCl
(Catalog# : 179825, Cas# :
1797989-42-4
)
CHIR99021, also known as CT99021, is a glycogen synthase kinase 3β (GSK3β) inhibito
CDDO
(Catalog# : 92304, Cas# :
218600-44-3
)
CDDO is a synthetic oleanane triterpenoid that blocks the cellular synthesis of induc
CVT-10216
(Catalog# : 179818, Cas# :
1005334-57-5
)
CVT-10216 is a Potent and selective, reversible inhibitor of aldehyde dehydrogenase 2
Carubicin HCl
(Catalog# : 17914, Cas# :
52794-97-5
)
Carubicin HCl is an anthracycline antineoplastic antibiotic isolated from the bacteri
Cambinol
(Catalog# : 178313, Cas# :
14513-15-6
)
Cambinol is a SIRT inhibitor. It inhibits expression of pro-inflammatory cytokines, i
2-chloro-4-(methylamino) pyrimidine-5-carbaldehyde
(Catalog# : 1781601, Cas# :
839708-50-8
)
2-chloro-4-(methylamino) pyrimidine-5-carbaldehyde
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Dabogratinib ( TYRA-300 )
(Catalog# : 24073, Cas# :
2800223-30-5
)
Dabogratinib ( TYRA-300 ) is an Oral Selective FGFR3 Inhibitor (IC50 = 11 nM) for the
AF710B
(Catalog# : 25205, Cas# :
N/A
)
AF710B is a highly selective and potent allosteric agonist for M1 muscarinic and σ1
MAT2A inhibitor 5
(Catalog# : 25204, Cas# :
2957874-18-7
)
MAT2A inhibitor 5 has a high potency for inhibiting MAT2A and a remarkable selectivit
(Rac)-AF710B
(Catalog# : 24083, Cas# :
1235733-73-9
)
AF-710B is an agonist of sigma and M1 muscarinic receptors; AF710B is an enantiomer o
Flurpiridaz-nonradiolabeled
(Catalog# : 25203, Cas# :
863888-33-9
)
Flurpiridazis a promising novel cardiac PET imaging tracer formed by the radiolabelin
Flurpiridaz-Precursor
(Catalog# : 25202, Cas# :
863888-32-8
)
Flurpiridaz-Precursor in stock.
KL1333
(Catalog# : 25201, Cas# :
1800405-30-4
)
KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinon
Palupiprant ( E7046 )
(Catalog# : 24055, Cas# :
1369489-71-3
)
E7046 is a potent and selective antagonist of the type 4 prostaglandin E2 (PGE2) rece
Oveporexton ( TAK-861 )
(Catalog# : 25194, Cas# :
2460722-04-5
)
Oveporexton isan oral small molecule selective orexin type-2 receptor (OX2R) agonist.
VT-3989
(Catalog# : 25200, Cas# :
2506273-81-8
)
VT3989, a first-in-class potent oral TEAD palmitoylation inhibitor, disrupts YAP tran