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MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
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Proteases
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TGF-beta/Smad
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Deuterated
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
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Iodos
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Name Index C
3-chloro-4-(pyridin-2-ylmethoxy)aniline
(Catalog# : 82716, Cas# :
524955-09-7
)
Coming soon!
6-Chloro-1-Indanone
(Catalog# : 81934, Cas# :
14548-38-0
)
Coming soon!
(Cbz-4-aminomethyl)piperidine
(Catalog# : 81804, Cas# :
132431-09-5
)
Coming soon!
1-Cbz-3-aminopyrrolidine hydrochloride
(Catalog# : 81735, Cas# :
1159822-27-1
)
Coming soon!
2-Cyclopropyl-4-(4-fluorophenyl)quinoline-3-carbaldehyde
(Catalog# : 81309, Cas# :
121660-37-5
)
Related API & intermediates:Cas#147526-32-7 Pitavastatin CalciumCas# 24922-02-9 E
[2-Cyclopropyl-4-(4-fluorophenyl)-quinolin-3-ylmethyl]-triphenyl-phosphonium bromido
(Catalog# : 81308, Cas# :
154057-58-6
)
Related API & intermediates:Cas#147526-32-7 Pitavastatin CalciumCas# 24922-02-9 E
2-Cyclopropyl-3-[(diphenylphosphinyl)methyl]-4-(4-fluorophenyl)quinolin
(Catalog# : 81307, Cas# :
146578-99-6
)
Related API & intermediates:Cas#147526-32-7 Pitavastatin CalciumCas# 24922-02-9 E
(2-Cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl)methanol
(Catalog# : 81305, Cas# :
121660-11-5
)
Related API & intermediates:Cas#147526-32-7 Pitavastatin CalciumCas# 24922-02-9 E
3-Chloro-4-methoxybenzaldehyde
(Catalog# : 81004, Cas# :
4903-09-7
)
Cooming soon!
CEP-33779
(Catalog# : 73105, Cas# :
1257704-57-6
)
CEP33779 is a selective JAK2 inhibitor with IC50 of 1.8 nM. CEP33779(< 3 M) inhibi
CID755673
(Catalog# : 73104, Cas# :
521937-07-5
)
CID 755673 is a selective and potent protein kinase D1-D3, PKC, CAK, PLK1 and CAMKII
CGI-1746
(Catalog# : 73103, Cas# :
910232-84-7
)
CGI1746 is a potent and highly selective small-molecule inhibitor of the Btk with IC5
CPI-169(racemate)
(Catalog# : 72804, Cas# :
1450655-76-1
)
CPI-169 racemate is the racemate form of CPI-169, which is a novel and potent EZH2 in
CHZ868(CHZ-868)
(Catalog# : 72001, Cas# :
1895895-38-1
)
CHZ868,a type II JAK inhibitor, would demonstrate activity in JAK inhibitor persisten
Capivasertib ( AZD5363 )
(Catalog# : 71805, Cas# :
1143532-39-1
)
Capivasertib is a novel pyrrolopyrimidine derivative, and an orally available inhibit
CO-1686(Rociletinib)
(Catalog# : 60701, Cas# :
1374640-70-6
)
CO-1686(Rociletinib) is an irreversible inhibitor of epidermal growth factor receptor
Coluracetam
(Catalog# : 52782, Cas# :
135463-81-9
)
Coluracetam(MKC-231) is a new choline uptake enhancer.
Chenodeoxycholic Acid
(Catalog# : 52781, Cas# :
474-25-9
)
Chenodeoxycholic Acid (CDCA), is a hydrophobic primary bile acid that activates nucle
Cerdulatinib (PRT062070, PRT2070)
(Catalog# : 52780, Cas# :
1369761-01-2
)
Cerdulatinib (PRT-062070) is an oral active, multi-targeted tyrosine kinase inhibitor
Cediranib
(Catalog# : 52779, Cas# :
288383-20-0
)
Cediranib (AZD2171) is a highly potent VEGFR(KDR) inhibitor with IC50 of <1 nM, al
Cabozantinib S-malate
(Catalog# : 52778, Cas# :
1140909-48-3
)
Cabozantinib S-malate (XL184, BMS-907351) is a potent VEGFR2 inhibitor with IC50 of 0
Cabozantinib
(Catalog# : 52777, Cas# :
849217-68-1
)
Cabozantinib (XL184, BMS-907351) is a potent VEGFR2 inhibitor with IC50 of 0.035 nM a
CX-5461
(Catalog# : 52748, Cas# :
1138549-36-6
)
CX-5461 is an inhibitor of rRNA synthesis, selectively inhibits Pol I-driven transcri
CZC24832
(Catalog# : 52735, Cas# :
1159824-67-5
)
CZC24832 is a selective inhibitor of PI 3-kinase (IC50 = 1.0 M in a PI 3-K-dependent
Canagliflozin
(Catalog# : 52724, Cas# :
842133-18-0
)
Canagliflozin(JNJ 28431754; TA 7284) is a highly potent and selective SGLT2 inhibitor
CAY10603
(Catalog# : 52705, Cas# :
1045792-66-2
)
CAY10603 is a potent and selective inhibitor of HDAC6 with IC50 of 2 pM, as compared
CCT128930
(Catalog# : 52635, Cas# :
885499-61-6
)
CCT128930 is a novel potent ATP-competitive, selective Akt2 inhibitor with an IC50 of
CDK4-IN-1
(Catalog# : 52610, Cas# :
1256963-02-6
)
CDK4 inhibitor is a novel and specific CDK4/Cyclin D1 inhibitor with an IC50 of 10 nM
Carfilzomib
(Catalog# : 52608, Cas# :
868540-17-4
)
Carfilzomib (PR-171) is an irreversible proteasome inhibitor with IC50 of <5 nM.
CZC-54252
(Catalog# : 52566, Cas# :
1191911-27-9
)
CZC-54252 is a potent inhibitor of LRRK2 with IC50s of 1.28 nM and 1.85 nM for wild-t
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Dabogratinib ( TYRA-300 )
(Catalog# : 24073, Cas# :
2800223-30-5
)
Dabogratinib ( TYRA-300 ) is an Oral Selective FGFR3 Inhibitor (IC50 = 11 nM) for the
AF710B
(Catalog# : 25205, Cas# :
N/A
)
AF710B is a highly selective and potent allosteric agonist for M1 muscarinic and σ1
MAT2A inhibitor 5
(Catalog# : 25204, Cas# :
2957874-18-7
)
MAT2A inhibitor 5 has a high potency for inhibiting MAT2A and a remarkable selectivit
(Rac)-AF710B
(Catalog# : 24083, Cas# :
1235733-73-9
)
AF-710B is an agonist of sigma and M1 muscarinic receptors; AF710B is an enantiomer o
Flurpiridaz-nonradiolabeled
(Catalog# : 25203, Cas# :
863888-33-9
)
Flurpiridazis a promising novel cardiac PET imaging tracer formed by the radiolabelin
Flurpiridaz-Precursor
(Catalog# : 25202, Cas# :
863888-32-8
)
Flurpiridaz-Precursor in stock.
KL1333
(Catalog# : 25201, Cas# :
1800405-30-4
)
KL1333 is an orally available, small organic molecule that reacts with NAD(P)H:quinon
Palupiprant ( E7046 )
(Catalog# : 24055, Cas# :
1369489-71-3
)
E7046 is a potent and selective antagonist of the type 4 prostaglandin E2 (PGE2) rece
Oveporexton ( TAK-861 )
(Catalog# : 25194, Cas# :
2460722-04-5
)
Oveporexton isan oral small molecule selective orexin type-2 receptor (OX2R) agonist.
VT-3989
(Catalog# : 25200, Cas# :
2506273-81-8
)
VT3989, a first-in-class potent oral TEAD palmitoylation inhibitor, disrupts YAP tran