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DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
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TGF-beta/Smad
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
Stem Cells & Wnt
TGF-beta/Smad
Ubiquitin
Vitamin D Related
PROTAC
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Name Index C
CM-272
(Catalog# : 2071538, Cas# :
1846570-31-7
)
CM-272 is a first-in-class reversible dual small molecule inhibitor against G9a and D
2-Cyano-4-fluorobenzaldehyde
(Catalog# : 2062317, Cas# :
77532-90-2
)
3-chloro-1-benzothiophene-2-carbonyl chloride
(Catalog# : 2062306, Cas# :
21815-91-8
)
5-chloro-2,6-dimethoxy-4-methyl-8-nitroquinoline
(Catalog# : 2062026, Cas# :
189746-21-2
)
4-(3-Chloro-2-fluoroanilino)-6-hydroxy-7-methoxyquinazoline
(Catalog# : 2062022, Cas# :
612501-52-7
)
2-chloro-6-methoxy-4-methylquinoline
(Catalog# : 2062014, Cas# :
6340-55-2
)
CaCCinh-A01
(Catalog# : 2061702, Cas# :
407587-33-1
)
CaCCinh-A01, also known as TMEM16 Blocker I, is a TMEM16 Blocker. CaCCinh-A01 is a no
CLEFMA
(Catalog# : 615201, Cas# :
1246964-32-8
)
CLEFMA has anti-proliferative activity in H441 cells. CLEFMA may induce autophagic ce
CMPD1
(Catalog# : 2061307, Cas# :
41179-33-3
)
CMPD1 is an inhibitor of MK2 activation, primarily inhibiting tubulin polymerisation
CGP52411
(Catalog# : 2061306, Cas# :
145915-58-8
)
CGP52411, also known as DAPH, is a selective inhibitor of the epidermal growth factor
CADD522
(Catalog# : 2051505, Cas# :
199735-88-1
)
CADD522 is a potent inhibitor of runt-related transcription factor-2 (RUNX2)-DNA bind
2-Chloro-7-fluoro-quinoline-3-carbaldehyde
(Catalog# : S-204160, Cas# :
745830-16-4
)
cupreine
(Catalog# : S-203042, Cas# :
524-63-0
)
CC-885
(Catalog# : 2041501, Cas# :
1010100-07-8
)
CC-885 is a potent Cereblon Modulator with potent antitumor activity mediated through
CC-90009
(Catalog# : 203071, Cas# :
1860875-51-9
)
CC-90009 is a modulator of cereblon (CRBN), which is part of the cullin 4-RING E3 ubi
5-Chloro-2,6-Dimethoxy-4-Methylquinoline
(Catalog# : 4281903, Cas# :
189746-19-8
)
5-Chloro-2,6-Dimethoxy-4-Methylquinoline, CAS 189746-19-8, is a key drug intermediate
Cenicriviroc Mesylate
(Catalog# : S510901, Cas# :
497223-28-6
)
Cenicriviroc (CVC) is an oral, once-daily, potent immunomodulator that blocks two che
CLP-290
(Catalog# : 193286, Cas# :
1181083-81-7
)
CLP-290 is a novel KCC2 modulator and prodrug of CLP-257, highly selective for KCC2 o
CT-1812
(Catalog# : 193283, Cas# :
1802632-22-9
)
CT-1812 is a first-in-class, orally available sigma-2/PGRMC1 antagonist (alpha beta o
Clofilium Tosylate
(Catalog# : 193181, Cas# :
92953-10-1
)
Clofilium Tosylate is a K+ channel blocker, cardiac depressant, and anti-arrhythmic a
Cevipabulin fumarate
(Catalog# : 193124, Cas# :
849550-67-0
)
Cevipabulin fumarate (TTI-237 fumarate) is an oral active, microtubule-active antitum
Conteltinib
(Catalog# : 19342, Cas# :
1384860-29-0
)
Conteltinib is a tyrosine kinase inhibitor and an antineoplastic.
C25-140
(Catalog# : 192274, Cas# :
1358099-18-9
)
C25-140 is the first in class protein-protein interaction inhibitor of a RING-E3 liga
CCT-137690
(Catalog# : 192192, Cas# :
1095382-05-0
)
CCT137690, an aurora kinase inhibitor CCT137690, is a highly selective, orally bioava
CAY10602
(Catalog# : 191285, Cas# :
374922-43-7
)
CAY10602 is a SIRT1 activator. CAY10602 was derived from high throughput screening fo
Cilofexor ( GS-9674 )
(Catalog# : 19132, Cas# :
1418274-28-8
)
Cilofexor (also known as GS-9674) is a nonsteroidal farnesoid X receptor (FXR) agonis
CCT241736
(Catalog# : 1812283, Cas# :
1402709-93-6
)
CCT241736 is a potent and orally active and dual FLT3-Aurora inhibitor.
CA-4948
(Catalog# : 1811292, Cas# :
1801343-74-7
)
CA-4948 is a bioactive chemical.
CCT129202
(Catalog# : 1810291, Cas# :
942947-93-5
)
CCT129202 is an inhibitor of Aurora kinase activity and displays a favorable antineop
CBM 301940
(Catalog# : 1810232, Cas# :
902146-11-6
)
CBM 301940 is a potent malonyl-CoA decarboxylase inhibitor that is orally bioavailabl
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
Atebimetinib
(Catalog# : 25148, Cas# :
2669009-92-9
)
Atebimetinib (IMM-1-104) is an oral, small-molecule allosteric inhibitor of the MEK1
Acoramidis hydrochloride
(Catalog# : 24068, Cas# :
2242751-53-5
)
Acoramidis is an oral, potent, and highly selective small molecule transthyretin (TTR
Crelosidenib
(Catalog# : 24101, Cas# :
2230263-60-0
)
Crelosidenib is an isocitrate dehydrogenase 1 (IDH1) inhibitor.
LOXO-435
(Catalog# : 25080, Cas# :
2833703-74-3
)
LOXO-435 is a selective small molecule inhibitor of FGFR3. It is active against both
MAT2A-IN-9
(Catalog# : 25147, Cas# :
2439277-80-0
)
MAT2A-IN-9 (compound 167), a 2-oxoquinazoline derivative, is a potent MAT2A (methioni
Gridegalutamide
(Catalog# : 25138, Cas# :
2446928-30-7
)
Gridegalutamide, also known as BMS-986365 and CC-94676, is a heterobifunctional, firs
Chiauranib
(Catalog# : 25146, Cas# :
1256349-48-0
)
Chiauranib also known as orally available, small molecule inhibitor of select serine-
Atuzabrutinib
(Catalog# : 25145, Cas# :
1581714-49-9
)
Atuzabrutinib, also known as PRN 473, is a Bruton's tyrosine kinase inhibitor.
Andamertinib
(Catalog# : 25144, Cas# :
2254145-43-0
)
Andamertinib is an epidermal growth factor receptor tyrosine kinase inhibitor. It is
MEN-1703
(Catalog# : 25143, Cas# :
2769008-22-0
)