CMP-5 2HCl
Catalog No: 24161
CAS Number: 2309409-79-6
Purity: 98% Min.
CMP-5 is a potent, specific, and selective PRMT5 inhibitor, while displays no activity against PRMT1, PRMT4, and PRMT7 enzymes.
For research use only. We do not sell to patients.
Chemical Information
| Name | CMP-5 2HCl |
|---|---|
| Iupac Chemical Name | 1-(9-ethyl-9H-carbazol-3-yl)-N-(pyridin-2-ylmethyl)methanamine dihydrochloride |
| Synonyms | CMP5; CMP-5; CMP 5; CMP5 HCl; CMP5 hydrochloride; |
| Molecular Formula | C21H23Cl2N3 |
| Molecular Weight | 388.33 |
| Smile | CCN1C2=C(C=C(C=C2)CNCC3=NC=CC=C3)C4=C1C=CC=C4.Cl.Cl |
| InChiKey | VWDPNMAEGCNJGR-UHFFFAOYSA-N |
| InChi | InChI=1S/C21H21N3.2ClH/c1-2-24-20-9-4-3-8-18(20)19-13-16(10-11-21(19)24)14-22-15-17-7-5-6-12-23-17;;/h3-13,22H,2,14-15H2,1H3;2*1H |
| CAS Number | 2309409-79-6 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid |
|---|---|
| Purity | 98% Min. |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Alinari, L.; Mahasenan, K. V.; Yan, F.; Karkhanis, V.; Chung, J. H.; Smith, E. M.; Quinion, C.; Smith, P. L.; Kim, L.; Patton, J. T.; Lapalombella, R.; Yu, B.; Wu, Y.; Roy, S.; De Leo, A.; Pileri, S.; Agostinelli, C.; Ayers, L.; Bradner, J. E.; Chen-Kiang, S.; Elemento, O.; Motiwala, T.; Majumder, S.; Byrd, J. C.; Jacob, S.; Sif, S.; Li, C.; Baiocchi, R. A. Selective inhibition of protein arginine methyltransferase 5 blocks initiation and maintenance of B-cell transformation. Blood 2015, 125, 2530−2543.
Chemical Structure
