Calderasib ( MK-1084 )

Catalog No: 26A006

CAS Number: 2641216-67-1

Purity: ≧98.0%

Calderasib (MK-1084) is an orally available inhibitor of the oncogenic KRAS substitution mutation G12C, with potential antineoplastic activity.

For research use only. We do not sell to patients.

Name	Calderasib ( MK-1084 )
Iupac Chemical Name	19-chloro-22-[(2S,5R)-2,5-dimethyl-4-prop-2-enoylpiperazin-1-yl]-13,16-difluoro-3-propan-2-yl-8,11-dioxa-1,4,23,26-tetrazapentacyclo[16.6.2.02,7.012,17.021,25]hexacosa-2(7),3,5,12,14,16,18,20,22,25-decaen-24-one
Synonyms	Calderasib ; MK-1084 ; MK1084 ; MK 1084
Molecular Formula	C32H31ClF2N6O4
Molecular Weight	636.21
Smile	O=C1N=C(N2[C@@H](C)CN(C(C=C)=O)[C@H](C)C2)C3=CC(Cl)=C4C5=C(F)C=CC(F)=C5OCCOC6=C(C(C(C)C)=NC=C6)N1C3=N4
InChiKey	BBIVCWWQPMOKAC-MSOLQXFVSA-N
InChi	InChI=1S/C32H31ClF2N6O4/c1-6-24(42)39-14-18(5)40(15-17(39)4)30-19-13-20(33)27-25-21(34)7-8-22(35)29(25)45-12-11-44-23-9-10-36-26(16(2)3)28(23)41(31(19)37-27)32(43)38-30/h6-10,13,16-18H,1,11-12,14-15H2,2-5H3/t17-,18+/m1/s1
CAS Number	2641216-67-1
Related CAS	2641216-67-1

Packaging	Price	Availability	Purity	Shipping Time
Bulk		Enquiry	Enquiry	Enquiry

Formulation	Off-white solid
Purity	≧98.0%
Storage	Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
Solubility	Soluble in DMSO (DMSO : ≥ 100 mg/mL)
Handling	Refer to MSDS
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code	2934200090

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