AZD3229
Catalog No: 191287
CAS Number: 2248003-60-1
Purity: >98%
AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors. AZD3229 demonstrates potent single digit nM growth inhibition across a broad cell panel, with good margin to KDR-driven effects.
For research use only. We do not sell to patients.
Chemical Information
| Name | AZD3229 |
|---|---|
| Iupac Chemical Name | N-{4-[(6,7-dimethoxyquinazolin-4-yl)oxy]phenyl}-2-[4-(propan-2-yl)-1H-1,2,3-triazol-1-yl]acetamide |
| Synonyms | AZD3229; AZD-3229; AZD 3229; |
| Molecular Formula | C24H26FN7O3 |
| Molecular Weight | 479.5164 |
| Smile | O=C(NC1=CC=C(NC2=C3C(F)=CC(OCCOC)=CC3=NC=N2)C=C1)CN4N=NC(C(C)C)=C4 |
| InChiKey | FLJOFQUXYAWOPE-UHFFFAOYSA-N |
| InChi | InChI=1S/C24H26FN7O3/c1-15(2)21-12-32(31-30-21)13-22(33)28-16-4-6-17(7-5-16)29-24-23-19(25)10-18(35-9-8-34-3)11-20(23)26-14-27-24/h4-7,10-12,14-15H,8-9,13H2,1-3H3,(H,28,33)(H,26,27,29) |
| CAS Number | 2248003-60-1 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid to white solid |
|---|---|
| Purity | >98% |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
