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Anlotinib HCl ( AL-3818 )

Catalog No: 1811211
CAS Number: 1360460-82-7
Purity: ≧98.0%

Anlotinib is a novel oral tyrosine kinase inhibitor (TKI) targeting c-kit, platelet-derived growth factor receptors, fibroblast growth factor receptor, and vascular endothelial growth factor receptor with potential antineoplastic and anti-angiogenic activities.

For research use only. We do not sell to patients.

Chemical Information

NameAnlotinib HCl ( AL-3818 )
Iupac Chemical Name1-(((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropan-1-amine dihydrochloride
SynonymsAL3818 ; AL-3818 ; AL 3818 ; Anlotinib ; Anlotinib HCl ; Anlotinib dihydrochloride ; Catequentinib
Molecular FormulaC23H24Cl2FN3O3
Molecular Weight480.3614
SmileNC1(COC2=C(OC)C=C3C(OC4=C(F)C5=C(NC(C)=C5)C=C4)=CC=NC3=C2)CC1.[H]Cl.[H]Cl
InChiKeyUUAKQNIPIXQZFN-UHFFFAOYSA-N
InChiInChI=1S/C23H22FN3O3.2ClH/c1-13-9-15-16(27-13)3-4-19(22(15)24)30-18-5-8-26-17-11-21(20(28-2)10-14(17)18)29-12-23(25)6-7-23;;/h3-5,8-11,27H,6-7,12,25H2,1-2H3;2*1H
CAS Number1360460-82-7
Related CAS1058156-90-3 (free base) 1360460-82-7 (HCl)

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
BulkEnquiryEnquiryEnquiry
Request Bulk Quote Download MSDS Tel : +86-177 0271 9238   Email : sales@sun-shinechem.com
FormulationOff-white solid to white solid
Purity≧98.0%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilityWate 96 mg/mL (199.85 mM) ;Ethanol Insoluble ; DMSO 48 mg/mL (99.93 mM).
HandlingRefer to MSDS operation
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
HS Code2934200090
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

1811211 - Anlotinib HCl ( AL-3818 ) | CAS 1360460-82-7

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