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PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
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GPCR & G Protein
Metabolism
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Immunology & Inflammation
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Cas Index 9
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Cas Index 9
937272-79-2 | Pacritinib ( SB1518 )
(Catalog# : 122941)
Pacritinib(SB1518) is a highly selective kinaseinhibitorwith specificity for JAK2, FL
955977-50-1 | PI-3065
(Catalog# : 122908)
PI-3065 is a novel potent and selective PI3K p110 inhibitor with IC50 of 15 nM; exhib
939791-38-5 | PF-562271 benzenesulfonate salt
(Catalog# : 101919)
PF-562271 is an orally bioavailable small molecule and ATP-competitive focal adhesion
900305-37-5 | PFI-4
(Catalog# : 82406)
PFI-4 is a potent and selective BRPF1 bromodomain inhibitor (IC50 = 80 nM). Exhibits
918505-84-7 | PLX-4720
(Catalog# : 52592)
PLX 4720 is a potent and selective inhibitor of B-RafV600E(IC50=13 nM) and c-Raf-1Y34
914913-88-5 | Palomid 529
(Catalog# : 52591)
Palomid 529 (P529) is a novel potent inhibitor of both the mTORC1 and mTORC2 complexe
929016-96-6 | Pracinostat
(Catalog# : 52552)
Pracinostat(SB939) is a potent pan-HDAC inhibitor with IC50 of 40-140 nM with excepti
931706-15-9 | PPQ-102
(Catalog# : 52233)
PPQ-102 is a potent CFTR inhibitor which can completely inhibited CFTR chloride curre
943319-70-8 | Ponatinib (AP24534)
(Catalog# : 52107)
Ponatinib (AP24534) is a novel, potent multi-target inhibitor ofAbl, PDGFR, VEGFR2, F
950769-58-1 | Quizartinib
(Catalog# : 82703)
Quizartinib is a second-generation FLT3 inhibitor for Flt3(ITD/WT) with IC50 of 1.1 n
93265-81-7 | Ropidoxuridine
(Catalog# : 20595)
Ropidoxuridine is a novel, orally available, thymidine analogue and prodrug for IUdR,
925206-65-1 | RRX-001
(Catalog# : 233901)
RRx-001 is a highly selective NLRP3 inhibitor with vascular normalization and tumor a
946150-57-8 | Remetinostat
(Catalog# : 193111)
Remetinostat, also known as SHP-141, is a topical formulation containing the histone
920113-03-7 | Riviciclib HCl
(Catalog# : 179131)
Riviciclib, also known as P276-00 , is a flavone and cyclin dependent kinase (CDK) in
947620-48-6 | RVT-501
(Catalog# : 17917)
RVT-501, also known as E-6005, is a phosphodiesterase 4 (PDE-4) inhibitor potentially
914462-92-3 | Rolapitant HCl
(Catalog# : 17030609)
Rolapitant, also known as SCH-619734, is an orally bioavailable, centrally-acting, se
939981-39-2 | RO5045337
(Catalog# : 16071112)
RO5045337, also known as R7112, RG7112, is a MDM2 antagonist with potential antineopl
926037-48-1 | Radotinib
(Catalog# : 011307)
Radotinib is an orally available, a second-generation tyrosine kinase inhibitor of Bc
941678-49-5 | Ruxolitinib
(Catalog# : 01118)
Ruxolitinib is the first potent, selective, JAK1/2 inhibitor to enter the clinic with
946128-88-7 | Ro 5126766
(Catalog# : 010812)
Ro 5126766 is a potent and selective dual RAF/MEK inhibitor. For SK-MEL-28, SK-MEL-2,
923032-37-5 | Refametinib
(Catalog# : 010810)
Refametinib is an orally bioavailable selective MEK inhibitor with potential antineop
901119-35-5 | R788
(Catalog# : 122928)
Fostamatinib is a small molecule Syk kinase inhibitor with potential anti-inflammator
927880-90-8 | RAF265
(Catalog# : 122202)
RAF265 is a potent selective inhibitor of C-Raf/B-Raf/B-Raf V600E with IC50 of 3-60 n
928025-63-2 | (R)-1-Boc-3-Isopropylpiperazine
(Catalog# : 81908)
Coming soon!
955979-06-3 | (R)-tert-Butyl 2-isopropylpiperazine-1-carboxylate hydrochloride
(Catalog# : 81903)
Coming soon!
911222-45-2 | Rabusertib(LY2603618)
(Catalog# : 52807)
LY2603618(IC-83) is a potent and selective small molecule inhibitor of Chk1 protein k
956697-53-3 | Sonidegib (LDE-225)
(Catalog# : 21232)
Sonidegib, also known as, erismodegib, LDE225, NVP-LDE225, is an orally bioavailable
910562-15-1 | Simenepag
(Catalog# : 1810172)
Simenepag, also known as AGN-210676, is a small molecule prostaglandin E2 receptor ag
923359-38-0 | SAR407899 free base
(Catalog# : 185115)
SAR407899 is a potent and selective Rho kinase inhibitor with promising antihypertens
927871-76-9 | S107 HCl
(Catalog# : 1791111)
S107 is a Type 1 ryanodine receptor (RyR1) stabilizer; binds RyR1 and enhances the bi
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
1393466-87-9 | PLX8394
(Catalog# : 20613)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
2365193-22-0 | Zelasudil
(Catalog# : 24014)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
2134675-36-6 | Ziftomenib ( KO-539 )
(Catalog# : 24013)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
1640282-42-3 | Zunsemetinib
(Catalog# : 24012)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
2728667-27-2 | Zongertinib
(Catalog# : 24011)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
2272904-53-5 | Zasocitinib
(Catalog# : 24010)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
2503036-46-0 | RNK-05047
(Catalog# : 24008)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
1001288-58-9 | Asengeprast (FT011)
(Catalog# : 24009)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
2490431-16-6 | ERAS-801 ( JGK-068S )
(Catalog# : 20635)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
209746-59-8 | T-1095
(Catalog# : 24004)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).