Palomid 529 (P529) is a novel potent inhibitor of both the mTORC1 and mTORC2 complexes with a GI50 of<35 M in the NCI-60 cell lines panel; reduces phosphorylation of pAktS473, pGSK3S9, and pS6 but no effect observed on pMAPK or pAktT308
For research use only. We do not sell to patients.
| Name | Palomid 529 |
|---|---|
| Molecular Formula | C24H22O6 |
| Molecular Weight | 406.43 |
| Smile | CC(c1ccc2c(c1)c(=O)oc3c2cc(c(c3)OCc4ccc(cc4)OC)OC)O |
| InChiKey | YEAHTLOYHVWAKW-UHFFFAOYSA-N |
| InChi | InChI=1S/C24H22O6/c1-14(25)16-6-9-18-19-11-22(28-3)23(12-21(19)30-24(26)20(18)10-16)29-13-15-4-7-17(27-2)8-5-15/h4-12,14,25H,13H2,1-3H3 |
| CAS Number | 914913-88-5 |
| MDL | MFCD18633224 |
| Related CAS |
| Packaging | Price | Availability | Purity | Shipping Time |
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| Bulk | Enquiry | Enquiry | Enquiry |
| Purity | 98% |
|---|---|
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| Cell study | |
| Animal study | |
| Clinical study |