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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
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TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
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Neuronal Signaling
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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Membrane Transporter/Ion Channel
others
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Cas Index 9
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Cas Index 9
908112-43-6 | SNX-2112
(Catalog# : 179815)
SNX-2112, also known as PF 04928473, is an Hsp90 inhibitor which is currently undergo
940929-33-9 | SB-743921 HCl
(Catalog# : 17011609)
SB-743921 is a synthetic small molecule with potential antineoplastic properties. SB-
923262-96-8 | SAR407899 HCl
(Catalog# : 17011606)
SAR407899 is a potent and selective Rho kinase inhibitor with promising antihypertens
910462-43-0 | 4SC-202
(Catalog# : 161227110)
4SC-202 is an orally bioavailable benzamide and inhibitor of human class I histone de
909089-13-0 | SKL2001
(Catalog# : 16122784)
SKL2001 is a novel agonist of the Wnt/-catenin pathway that disrupts the Axin/-cateni
913822-46-5 | SC75741
(Catalog# : 16122748)
SC75741 is a potent NF-B inhibitor with EC50 of 200 nM.SC75741 shows immunosuppressiv
906805-42-3 | SCH 546738
(Catalog# : 161113)
SCH 546738 is a novel, potent and non-competitive small molecule CXCR3 antagonist wit
923604-59-5 | Simeprevir
(Catalog# : 16062201)
Simeprevir (formerly TMC435; trade name Olysio) is a drug for the treatment and cure
929901-49-5 | SGI-110
(Catalog# : 011806)
SGI-110 is a small molecule, DNMT inhibitor with demonstrated activity in restoring s
942183-80-4 | SCH772984
(Catalog# : 11106)
SCH772984 is a novel, specific inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respec
936487-67-1 | SF1126
(Catalog# : 010804)
SF1126 is a water soluble, small-molecule prodrug containing the pan-PI3K/mTOR inhibi
957135-43-2 | SM-164
(Catalog# : 122802)
SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP prot
912545-86-9 | SAG
(Catalog# : 92802)
SAG is a potent Smoothened (Smo) receptor agonist (Kd = 59 nM); antagonizes Cyclopami
946053-90-3 | (S)-4-Fluoro-2,3-dihydro-1H-inden-1-amine
(Catalog# : 91115)
Coming soon!
911417-87-3 | SLx-2119
(Catalog# : 91002)
SLx-2119(KD-025) is a small molecule and selective inhibitor of ROCK2 with IC50 of 10
916214-30-7 | (S)-1-Boc-3-Aminomethylpyrrolidine hydrochloride
(Catalog# : 83120)
Coming soon!
943760-74-5 | (1S)-1-(4-chloro-3-methylphenyl)ethanamine
(Catalog# : 81017)
Coming soon!
928659-17-0 | Triazavirin ( Riamilovir )
(Catalog# : 2071631)
Triazavirin (TZV, Riamilovir) is a broad-spectrum antiviral drug that is a nucleoside
925436-46-0 | tert-butyl 4-[[6-[2-(quinoxaline-2-carbonylamino)phenyl]imidazo[2,1-b][1,3]thiazol-3-yl]methyl]piperazine-1-carboxylate
(Catalog# : 2062035)
951395-08-7 | Tafamidis meglumine
(Catalog# : 193183)
Tafamidis meglumine , also known as Fx-1006 or PF-06291826, is a drug for the amelior
94497-51-5 | Tamibarotene
(Catalog# : 191254)
Tamibarotene, also known as SY-1425, is an orally active, synthetic retinoid, develop
903565-83-3 | Tofogliflozin
(Catalog# : 184311)
Tofogliflozin, also known as CSG 452, is a potent and high selective SGLT2 inhibitor
936091-14-4 | TG101209
(Catalog# : 17011726)
TG101209 is a novel and potent JAK2 inhibitor, which induced dose- and time-dependent
937039-45-7 | TC-H 106
(Catalog# : 17011720)
TC-H 106, also known as Pimelic Diphenylamide 106, is a class I HDAC inhibitor, demon
934369-14-9 | TY-52156
(Catalog# : 61118)
TY-52156 is a potent S1P3 receptor antagonist in a competitive manner, and the Ki val
925705-73-3 | TG100713
(Catalog# : 160926017)
TG100713 is an inhibitor of PI3-kinase (IC50 values are 24, 50, 165 and 215 nM for PI
905854-02-6 | Tivantinib
(Catalog# : 16070802)
Tivantinib (ARQ-197) is an orally bioavailable small molecule inhibitor of c-Met with
918633-87-1 | TH-302
(Catalog# : 011812)
TH-302 is selective hypoxia-activated prodrug targeting hypoxic regions of solid tumo
916141-36-1 | TCS 1102
(Catalog# : 121408)
TCS 1102 is a potent, dual orexin receptor antagonist (Ki values are 0.2 and 3 nM for
941685-27-4 | trimethyl-[2-[[4-(1H-pyrazol-4-yl)pyrrolo[2,3-d]pyrimidin-7-yl]methoxy]ethyl]silane
(Catalog# : 91701)
Coming soon!
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
1393466-87-9 | PLX8394
(Catalog# : 20613)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
2365193-22-0 | Zelasudil
(Catalog# : 24014)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
2134675-36-6 | Ziftomenib ( KO-539 )
(Catalog# : 24013)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
1640282-42-3 | Zunsemetinib
(Catalog# : 24012)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
2728667-27-2 | Zongertinib
(Catalog# : 24011)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
2272904-53-5 | Zasocitinib
(Catalog# : 24010)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
2503036-46-0 | RNK-05047
(Catalog# : 24008)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
1001288-58-9 | Asengeprast (FT011)
(Catalog# : 24009)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
2490431-16-6 | ERAS-801 ( JGK-068S )
(Catalog# : 20635)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
209746-59-8 | T-1095
(Catalog# : 24004)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).