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MAPK
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
Angiogenesis
Anti-infection
Apoptosis
Autophagy
Cell Cycle
Cytoskeleton
DNA Damage
Epigenetics
GPCR & G Protein
Immunology & Inflammation
JAK/STAT
MAPK
Membrane Transporter/Ion Channel
Metabolism
Neuronal Signaling
NF-κB
Protein Tyrosine Kinase
Proteases
PI3K/Akt/mTOR
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TGF-beta/Smad
Ubiquitin
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Cas Index 9
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Cas Index 9
911222-45-2 | Rabusertib(LY2603618)
(Catalog# : 52807)
LY2603618(IC-83) is a potent and selective small molecule inhibitor of Chk1 protein k
956697-53-3 | Sonidegib (LDE-225)
(Catalog# : 21232)
Sonidegib, also known as, erismodegib, LDE225, NVP-LDE225, is an orally bioavailable
910562-15-1 | Simenepag
(Catalog# : 1810172)
Simenepag, also known as AGN-210676, is a small molecule prostaglandin E2 receptor ag
923359-38-0 | SAR407899 free base
(Catalog# : 185115)
SAR407899 is a potent and selective Rho kinase inhibitor with promising antihypertens
927871-76-9 | S107 HCl
(Catalog# : 1791111)
S107 is a Type 1 ryanodine receptor (RyR1) stabilizer; binds RyR1 and enhances the bi
908112-43-6 | SNX-2112
(Catalog# : 179815)
SNX-2112, also known as PF 04928473, is an Hsp90 inhibitor which is currently undergo
940929-33-9 | SB-743921 HCl
(Catalog# : 17011609)
SB-743921 is a synthetic small molecule with potential antineoplastic properties. SB-
923262-96-8 | SAR407899 HCl
(Catalog# : 17011606)
SAR407899 is a potent and selective Rho kinase inhibitor with promising antihypertens
910462-43-0 | 4SC-202
(Catalog# : 161227110)
4SC-202 is an orally bioavailable benzamide and inhibitor of human class I histone de
909089-13-0 | SKL2001
(Catalog# : 16122784)
SKL2001 is a novel agonist of the Wnt/-catenin pathway that disrupts the Axin/-cateni
913822-46-5 | SC75741
(Catalog# : 16122748)
SC75741 is a potent NF-B inhibitor with EC50 of 200 nM.SC75741 shows immunosuppressiv
906805-42-3 | SCH 546738
(Catalog# : 161113)
SCH 546738 is a novel, potent and non-competitive small molecule CXCR3 antagonist wit
923604-59-5 | Simeprevir
(Catalog# : 16062201)
Simeprevir (formerly TMC435; trade name Olysio) is a drug for the treatment and cure
929901-49-5 | SGI-110
(Catalog# : 011806)
SGI-110 is a small molecule, DNMT inhibitor with demonstrated activity in restoring s
942183-80-4 | SCH772984
(Catalog# : 11106)
SCH772984 is a novel, specific inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respec
936487-67-1 | SF1126
(Catalog# : 010804)
SF1126 is a water soluble, small-molecule prodrug containing the pan-PI3K/mTOR inhibi
957135-43-2 | SM-164
(Catalog# : 122802)
SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP prot
912545-86-9 | SAG
(Catalog# : 92802)
SAG is a potent Smoothened (Smo) receptor agonist (Kd = 59 nM); antagonizes Cyclopami
946053-90-3 | (S)-4-Fluoro-2,3-dihydro-1H-inden-1-amine
(Catalog# : 91115)
Coming soon!
911417-87-3 | SLx-2119
(Catalog# : 91002)
SLx-2119(KD-025) is a small molecule and selective inhibitor of ROCK2 with IC50 of 10
916214-30-7 | (S)-1-Boc-3-Aminomethylpyrrolidine hydrochloride
(Catalog# : 83120)
Coming soon!
943760-74-5 | (1S)-1-(4-chloro-3-methylphenyl)ethanamine
(Catalog# : 81017)
Coming soon!
942271-61-6 | tert-butyl 4-(4-methylpiperazin-1-yl)-2-nitrobenzoate
(Catalog# : 24062)
95727-86-9 | 5-(Trifluoromethyl)picolinonitrile
(Catalog# : 24061)
928659-17-0 | Triazavirin ( Riamilovir )
(Catalog# : 2071631)
Triazavirin (TZV, Riamilovir) is a broad-spectrum antiviral drug that is a nucleoside
925436-46-0 | tert-butyl 4-[[6-[2-(quinoxaline-2-carbonylamino)phenyl]imidazo[2,1-b][1,3]thiazol-3-yl]methyl]piperazine-1-carboxylate
(Catalog# : 2062035)
951395-08-7 | Tafamidis meglumine
(Catalog# : 193183)
Tafamidis meglumine , also known as Fx-1006 or PF-06291826, is a drug for the amelior
94497-51-5 | Tamibarotene
(Catalog# : 191254)
Tamibarotene, also known as SY-1425, is an orally active, synthetic retinoid, develop
903565-83-3 | Tofogliflozin
(Catalog# : 184311)
Tofogliflozin, also known as CSG 452, is a potent and high selective SGLT2 inhibitor
936091-14-4 | TG101209
(Catalog# : 17011726)
TG101209 is a novel and potent JAK2 inhibitor, which induced dose- and time-dependent
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Products Catalog
Signaling Pathway
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Src
----
ALK
----
Syk
----
HIF
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
----
Eukaryotic Initiation Factor (eIF)
-- Cytoskeleton
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
----
Gap Junction Protein
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Ras
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
----
Bradykinin Receptor
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
----
Kallikrein
----
IRAK
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
----
Proton Pump
----
Potassium Channel
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
Mitochondrial Metabolism
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
----
Ketohexokinase(KHK)
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
Sigma Receptor
----
mAChR
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
----
Melanocortin Receptor
----
Glucosylceramide Synthase (GCS)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
----
Keap1-Nrf2
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
----
Bcr-Abl
----
FAK
----
RET
----
Phosphoglycerate Kinase (PGK)
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
----
Methionine Adenosyltransferase (MAT)
----
Lipase
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- TGF-beta/Smad
----
PKC
----
ROCK
----
TGF-beta/Smad
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
----
DUB
-- Vitamin D Related
----
VD/VDR
-- PROTAC
----
Molecular Glues
----
PROTACs
--
Antibody-drug Conjugate/ADC Related
--
Microbiology
-- Others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
----
Newest added products
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
1820812-16-5 | TAK-071
(Catalog# : 186269)
TAK-071 is a muscarinic M1 receptor positive allosteric modulator.
2750895-97-5 | MTX115325
(Catalog# : 186264)
MTX115325 is a potent, selective, brain-penetrant USP30 inhibitor with good drug-like
2166616-75-5 | LY-3381916
(Catalog# : 193123)
LY-3381916 is a potent, selective and brain penetrated inhibitor of IDO1 activity, bi
2376397-93-0 | Opakalim
(Catalog# : 25193)
Opakalim (BHV-7000) is an oral, small-molecule activator of Kv7.2/7.3 potassium chann
2488609-21-6 | DS68591889
(Catalog# : 25158)
DS68591889 (PTDSS1i) specifically inhibits PTDSS1, which catalyzes serine incorporati
944808-88-2 | CAY 10566
(Catalog# : 10403)
CAY 10566 is a potent selective SCD-1 inhibitor.
2308520-97-8 | Cadefrecitinib (GLPG-3667)
(Catalog# : 20509)
Cadefrecitinib (GLPG-3667) is an oral, small molecule inhibitor of the TYK2 kinase in
1802735-28-9 | QBS10072S
(Catalog# : 25190)
QBS10072S isa blood-brain-barrier (BBB) penetrative agent composed of a cytotoxic che
2377000-84-3 | Dencatistat
(Catalog# : 25177)
Dencatistat is an orally bioavailable, small molecule inhibitor of cytidine triphosph
1898207-64-1 | DS-1001b
(Catalog# : 25178)
DS-1001 is an oral brain-penetrant mutant IDH1 selective inhibitor.