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PI3K/Akt/mTOR
Epigenetics
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Angiogenesis
Apoptosis
Autophagy
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MAPK
Cytoskeletal Signaling
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+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
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GPCR & G Protein
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Cas Index 9
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Cas Index 9
923564-51-6 | Navitoclax (ABT-263)
(Catalog# : 16070102)
Navitoclax, also known as ABT-263, is an orally bioavailable, synthetic small-molecul
923288-90-8 | Nilotinib HCl hydrate
(Catalog# : 122901)
Nilotinib is an orally bioavailable aminopyrimidine-derivative Bcr-Abl tyrosine kinas
913830-15-6 | NS 9283
(Catalog# : 122828)
Coming soon!
95734-82-0 | Nedaplatin
(Catalog# : 122513)
Nedaplatin is a derivative of cisplatin and DNA damage agent.
940310-85-0 | NVP-BHG712
(Catalog# : 122213)
NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates betwee
956014-19-0 | Ns11021
(Catalog# : 120425)
Coming soon!
91419-53-3 | N-Boc-3-Cyanopiperidine
(Catalog# : 81713)
Coming soon!
951650-22-9 | NS11394
(Catalog# : 52567)
NS11394 is a potent and subtype-selective GABA(A) receptor-positive modulator; posses
923287-50-7 | Opicapone
(Catalog# : 6111514)
Opicapone(BIA 9-1067) is a long-acting, peripherally selective inhibitor of catechol-
936890-98-1 | OSI-027 HCl salt
(Catalog# : 161009007)
mTOR kinase inhibitor OSI-027 binds to and inhibits both the raptor-mTOR (TOR complex
951127-25-6 | Omarigliptin intermediate I
(Catalog# : 82718)
Coming soon!
919973-83-4 | OF-1
(Catalog# : 82407)
Selective BRPF1B and BRPF2 bromodomain inhibitor (Kd values are 100 and 500 nM respec
94790-37-1 | O-(Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium Hexafluorophosphate
(Catalog# : 81023)
Coming soon!
935888-69-0 | Oprozomib
(Catalog# : 52630)
Oprozomib (ONX 0912; PR047) is an orally bioavailable inhibitor for CT-L activity of
960374-59-8 | ONX-0914 ( PR-957 )
(Catalog# : 52013)
ONX-0914, an inhibitor of the LMP7 and LMP2 subunits of immunoproteasomes, has activi
903576-44-3 | Pitolisant HCl
(Catalog# : 20624)
Pitolisant, also known as Tiprolisant, BF2649 and Ciproxidine, is a histamine recepto
952021-60-2 | PF-477736
(Catalog# : 2071540)
PF-477736, also known as PF-00477736, is a potent CHK1 inhibitor with potential chemo
942425-68-5 | PHA-767491 HCl
(Catalog# : 184286)
PHA-767491, also known as CAY10572, is a potent, ATP-competitive dual cdc7/cdk9 inhib
939791-41-0 | PF-562271 HCl
(Catalog# : 179302)
PF-562271, also known as PF-562,271 and PF-271, is an orally bioavailable small molec
95153-31-4 | Perindoprilat
(Catalog# : 2017829)
Perindoprilat is a potent and long-acting angiotensin converting enzyme inhibitor, ca
908115-27-5 | PF 04929113
(Catalog# : 2017826)
PF-04929113, also known as SNX-5422; is a synthetic prodrug targeting the human heat-
950762-95-5 | PCI-34051
(Catalog# : 17022402)
PCI-34051 is a potent, histone deacetylase 8 (HDAC8)-specific inhibitor with >200-fol
944118-01-8 | Peficitinib (ASP015K, JNJ-54781532)
(Catalog# : 16122707)
Peficitinib (ASP015K, JNJ-54781532) is an orally bioavailable JAK inhibitor. Phase 3.
900185-02-6 | PIK-294
(Catalog# : 160926013)
PIK-294 is a highly selective inihibitor of the phosphoinositide 3-kinase (PI3K) p110
905579-51-3 | Pevonedistat
(Catalog# : 16071408)
Pevonedistat, also known as MLN-4924 and TAK-924, is a small molecule inhibitor of Ne
900185-01-5 | PIK-293
(Catalog# : 16062804)
PIK-293 is a PI3K inhibitor
900510-03-4 | PF-3274167
(Catalog# : 020101)
PF-3274167 is a high-affinity nonpeptide oxytocin receptor (OTR) antagonist, with Ki
942487-16-3 | PF-03814735
(Catalog# : 011105)
PF-03814735 is an orally bioavailable, ATP-competitive, reversible small-molecule Aur
956905-27-4 | PF-04217903
(Catalog# : 010807)
PF-04217903 is a selective ATP-competitive c-Met inhibitor with IC50 of 4.8 nM, susce
92623-83-1 | Pravadoline
(Catalog# : 010415)
Coming soon!
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
1393466-87-9 | PLX8394
(Catalog# : 20613)
PLX8394 is an orally bioavailable inhibitor of serine/threonine-protein kinase B-raf
2365193-22-0 | Zelasudil
(Catalog# : 24014)
Zelasudil is a potent, highly selective and orally-active inhibitor that targets Rho-
2134675-36-6 | Ziftomenib ( KO-539 )
(Catalog# : 24013)
Ziftomenib is an oral, potent, and selective small molecule inhibitor that targets th
1640282-42-3 | Zunsemetinib
(Catalog# : 24012)
Zunsemetinib is an investigational oral mitogen-activated protein kinase-activated pr
2728667-27-2 | Zongertinib
(Catalog# : 24011)
Zongertinib [BI 1810631] is a human epidermal growth factor receptor 2 (HER2) inhibit
2272904-53-5 | Zasocitinib
(Catalog# : 24010)
Zasocitinib is under development for the treatment of moderate to severe plaque psori
2503036-46-0 | RNK-05047
(Catalog# : 24008)
RNK-05047 is a PROTAC degrader of BRD4 which displays significant tumor growth inhibi
1001288-58-9 | Asengeprast (FT011)
(Catalog# : 24009)
Asengeprast (FT011) is an anti-fibrotic agent thatreduces mRNA expression of collagen
2490431-16-6 | ERAS-801 ( JGK-068S )
(Catalog# : 20635)
ERAS-801 ( JGK-068S ) is a potent EGFR inhibitor.
209746-59-8 | T-1095
(Catalog# : 24004)
T-1095 is a potent and selective inhibitor of Na+-glucose cotransporters (SGLTs).