PLX-4720
Catalog No: 52592
CAS Number: 918505-84-7
Purity: 98%
PLX 4720 is a potent and selective inhibitor of B-RafV600E(IC50=13 nM) and c-Raf-1Y340D/Y341D(IC50=6.7 nM); 10-fold selectivity for B-RafV600E than wild-type B-Raf.
For research use only. We do not sell to patients.
Chemical Information
| Name | PLX-4720 |
|---|---|
| Molecular Formula | C17H14ClF2N3O3S |
| Molecular Weight | 413.83 |
| Smile | CCCS(=O)(=O)Nc1ccc(c(c1F)C(=O)c2c[nH]c3c2cc(cn3)Cl)F |
| InChiKey | YZDJQTHVDDOVHR-UHFFFAOYSA-N |
| InChi | InChI=1S/C17H14ClF2N3O3S/c1-2-5-27(25,26)23-13-4-3-12(19)14(15(13)20)16(24)11-8-22-17-10(11)6-9(18)7-21-17/h3-4,6-8,23H,2,5H2,1H3,(H,21,22) |
| CAS Number | 918505-84-7 |
| MDL | MFCD14635203 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Purity | 98% |
|---|---|
| Handling | |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
