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Refametinib

Catalog No.: 010810
Cas No.: 923032-37-5
Purity : 98% 
010810 - Refametinib | CAS 923032-37-5

Catalog number : 010810

CAS number : 923032-37-5

Molecular Formula : C19H20F3IN2O5S 

Molecular Weight : 572.337 

Iupac Chemical Name : (S)-N-(3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)-6-methoxyphenyl)-1-(2,3-dihydroxypropyl)cyclopropane-1-sulfonamide 

Smile : O=S(C1(C[C@H](O)CO)CC1)(NC2=C(OC)C=C(F)C(F)=C2NC3=CC=C(I)C=C3F)=O

InChiKey : RDSACQWTXKSHJT-NSHDSACASA-N

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SynonymsBAY 869766; BAY 86-97661; RDEA-119; RDEA119 
Molecular FormulaC19H20F3IN2O5S 
Molecular Weight572.337 
AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileO=S(C1(C[C@H](O)CO)CC1)(NC2=C(OC)C=C(F)C(F)=C2NC3=CC=C(I)C=C3F)=O
InChiKeyRDSACQWTXKSHJT-NSHDSACASA-N
InChiInChI=1S/C19H20F3IN2O5S/c1-30-15-7-13(21)16(22)18(24-14-3-2-10(23)6-12(14)20)17(15)25-31(28,29)19(4-5-19)8-11(27)9-26/h2-3,6-7,11,24-27H,4-5,8-9H2,1H3/t11-/m0/s1
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Refametinib is an orally bioavailable selective MEK inhibitor with potential antineoplastic activity. 

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