RRX-001
Catalog No: 233901
CAS Number: 925206-65-1
Purity: ≧98.0%
RRx-001 is a highly selective NLRP3 inhibitor with vascular normalization and tumor associated macrophage polarization properties that resensitizes tumors to previously administered therapies. RRx-001 is under investigation in a Phase 3 trial for the treatment of small cell lung cancer (SCLC), and in a Phase 2 trial for protection against oral mucositis in first line head and neck cancer.
For research use only. We do not sell to patients.
Chemical Information
| Name | RRX-001 |
|---|---|
| Iupac Chemical Name | 2-bromo-1-(3,3-dinitroazetidin-1-yl)ethanone |
| Synonyms | RRX001 ; RRX 001 ; RRx-001 ; ABDNAZ |
| Molecular Formula | C5H6BrN3O5 |
| Molecular Weight | 268.02224 |
| Smile | O=[N+](C1([N+]([O-])=O)CN(C(CBr)=O)C1)[O-] |
| InChiKey | JODKFOVZURLVTG-UHFFFAOYSA-N |
| InChi | InChI=1S/C5H6BrN3O5/c6-1-4(10)7-2-5(3-7,8(11)12)9(13)14/h1-3H2 |
| CAS Number | 925206-65-1 |
| Related CAS | 925206-65-1 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | NLRP3 inhibitor |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
